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Assessment of the Myogenic and Metabolic Mechanism Influence in Cerebral Autoregulation Using Near-Infrared Spectroscopy

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dc.creatorCaicedo Dorado, Alexander
dc.creatorNaulaers, Gunnarspa
dc.creatorWolf, Martinspa
dc.creatorLemmers, Petraspa
dc.creatorVan Bel, Frankspa
dc.creatorAmeye, Lievekespa
dc.creatorVan Huffel, Sabine Vanspa
dc.date.accessioned2020-08-28T15:49:59Z
dc.date.available2020-08-28T15:49:59Z
dc.date.created2011-11-10spa
dc.description.abstractCerebral autoregulation is normally controlled via three different mechanisms, namely: the myogenic, the metabolic, and the neurogenic one. The myogenic mechanism responds efficiently to slow changes in mean arterial blood pressure (MABP) while the metabolic one is more efficient with fast changes. The neurogenic mechanism is not yet well understood. As changes in cerebral intravascular oxygenation (HbD), measured with near-infrared spectroscopy (NIRS), reflect changes in cerebral blood flow, the myogenic influence in the cerebral autoregulation can be assessed by analysis of HbD and MABP; the metabolic influence can be assessed by analysis of the HbD and the partial pressure of carbon dioxide (pCO2). We performed a transfer function analysis in order to calculate the gain and phase of the HbD/MABP and HbD/PCO2 subsystems. Due to the fact that cerebral autoregulation may be absent in sick premature infants, we then investigated how well these parameters could predict clinical outcome in this population.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1007/978-1-4614-1566-4_6
dc.identifier.issnISBN: 978-1-4614-1565-7
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/28880
dc.language.isoengspa
dc.publisherSpringer Naturespa
dc.relation.citationEndPage44
dc.relation.citationStartPage37
dc.relation.citationTitleAdvances in Experimental Medicine and Biology
dc.relation.citationVolumeVol. 737
dc.relation.ispartofAdvances in Experimental Medicine and Biology, ISBN: 978-1-4614-1565-7 Vol.737 (2011); pp. 37-44spa
dc.relation.urihttps://link.springer.com/chapter/10.1007/978-1-4614-1566-4_6spa
dc.rights.accesRightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.accesoRestringido (Acceso a grupos específicos)spa
dc.sourceAdvances in Experimental Medicine and Biologyspa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.keywordCerebral Blood Flowspa
dc.subject.keywordMean Arterial Blood Pressurespa
dc.subject.keywordCerebral Autoregulationspa
dc.subject.keywordGain Scorespa
dc.subject.keywordMetabolic Mechanismspa
dc.titleAssessment of the Myogenic and Metabolic Mechanism Influence in Cerebral Autoregulation Using Near-Infrared Spectroscopyspa
dc.title.TranslatedTitleEvaluación de la influencia del mecanismo miogénico y metabólico en la autorregulación cerebral mediante espectroscopia de infrarrojo cercanospa
dc.typebookParteng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaParte de librospa
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