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Correlation between arterial lactate and central venous lactate in children with sepsis

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dc.creatorFernández Sarmiento, Jaime
dc.creatorAraque, Paula
dc.creatorYepes, María
dc.creatorMulett, Hernando
dc.creatorTovar, Ximena
dc.creatorRodriguez, Fabio
dc.creator.googleFernández Sarmiento, Jaimespa
dc.creator.googleAraque, Paula
dc.creator.googleYepes, María
dc.creator.googleMulett, Hernando
dc.creator.googleTovar, Ximena
dc.creator.googleRodriguez, Fabio
dc.date.accessioned2019-02-04T17:40:31Z
dc.date.available2019-02-04T17:40:31Z
dc.date.created2016
dc.date.issued2016
dc.description.abstractIntroduction. Lactate is an important indicator of tissue perfusion. The objective of this study is to evaluate if there are significant differences between the arterial and central venous measurement of lactate in pediatric patients with sepsis and/or septic shock. Methods. Longitudinal retrospective observational study. Forty-two patients were included between the age of 1 month and 17 years, with a diagnosis of sepsis and septic shock, who were admitted to the intensive care unit of a university referral hospital. The lactate value obtained from an arterial blood sample and a central venous blood sample drawn simultaneously, and within 24 hours of admission to the unit, was recorded. Results. The median age was 2.3 years (RIC 0,3-15), with a predominance of males (71.4%), having a 2.5: 1 ratio to females. Most of the patients had septic shock (78.5%) of pulmonary origin (50.0%), followed by those of gastrointestinal origin (26.1%). Using Spearman's Rho, a 0.872 (p<0.001) correlation was found between arterial and venous lactate, which did not vary when adjusted for age (p<0.05) and the use of vasoactive drugs (p<0.05). Conclusion. There is a good correlation between arterial and venous lactate in pediatric patients with sepsis and septic shock, which is not affected by demographic variables or type of vasoactive support. Copyright © 2016 Jaime Fernández Sarmiento et al.eng
dc.format.mimetypeapplication/pdf
dc.identifier.issnISSN 2090-1305
dc.identifier.urihttp://repository.urosario.edu.co/handle/10336/19004
dc.language.isoengspa
dc.relation.citationTitleCritical Care Research and Practice
dc.relation.citationVolumeVol. 2016
dc.relation.ispartofCritical Care Research and Practice, ISSN: 2090-1305, Vol. 2016 (2016)spa
dc.relation.urihttp://downloads.hindawi.com/journals/ccrp/2016/7839739.pdfspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.rights.cchttps://creativecommons.org/licenses/by/4.0/spa
dc.source.bibliographicCitationNascente, A.P.M., Assunção, M., Guedes, C.J., Comparison of lactate values obtained from different sites and their clinical significance in patients with severe sepsis (2011) Sao Paulo Medical Journal, 129 (1), pp. 11-16spa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.ddcEnfermedadesspa
dc.subject.lembSepticemiaspa
dc.subject.lembSepsisspa
dc.titleCorrelation between arterial lactate and central venous lactate in children with sepsisspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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