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Glucose-6-phosphate dehydrogenase (G6PD). Response of the human erythrocyte and another cells to the decrease in their activity

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dc.creatorBonilla J.F.spa
dc.creatorSánchez M.C.spa
dc.creatorChuaire L.spa
dc.date.accessioned2020-05-26T00:04:45Z
dc.date.available2020-05-26T00:04:45Z
dc.date.created2007spa
dc.description.abstractGlucose-6-phosphate dehydrogenase is the first enzyme in the pentose phosphate pathway and the main intracellular source of reduced nicotidamineadenine nucleotidephosphate (NADPH), involved in diverse physiological processes such as antioxidant defense, (for instance in the erythrocyte) endothelial growth modulation, erithropoyesis, vascularization and phagocitosis, G6PDH deficiency is the most common X-chromosome-linked enzymopathy in human beings. Although it is present in any type cell, its absolute deficiency is incompatible with life. According to WHO, 400 million people are affected by G6PD deficiency in the world but in Colombia, the severe form prevalence is about 3% to 7%. There are no data related to slight and moderate alterations, that also have clinical effects. This paper reviews some G6PD biomolecular aspects, its classification according to activity and electrophoretic mobility, as well as some main clinical aspects related to its activity alteration. © 2007 Corporación Editora Médica del Valle.eng
dc.format.mimetypeapplication/pdf
dc.identifier.issn16579534
dc.identifier.issn01208322
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/23715
dc.language.isoengspa
dc.relation.citationEndPage75
dc.relation.citationIssueNo. 1
dc.relation.citationStartPage68
dc.relation.citationTitleColombia Medica
dc.relation.citationVolumeVol. 38
dc.relation.ispartofColombia Medica, ISSN:16579534, 01208322, Vol.38, No.1 (2007); pp. 68-75spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-34147143062&partnerID=40&md5=bf449b08546848be17625a9bbb1b19b6spa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordGlucose 6 phosphate dehydrogenasespa
dc.subject.keywordPentose phosphatespa
dc.subject.keywordReduced nicotinamide adenine dinucleotide phosphatespa
dc.subject.keywordAntioxidant activityspa
dc.subject.keywordArticlespa
dc.subject.keywordCell growthspa
dc.subject.keywordClinical featurespa
dc.subject.keywordColombiaspa
dc.subject.keywordDisease severityspa
dc.subject.keywordEndothelium cellspa
dc.subject.keywordEnzyme activityspa
dc.subject.keywordEnzyme electrophoresisspa
dc.subject.keywordErythrocytespa
dc.subject.keywordErythropoiesisspa
dc.subject.keywordGlucose 6 phosphate dehydrogenase deficiencyspa
dc.subject.keywordHemolysisspa
dc.subject.keywordHemolytic anemiaspa
dc.subject.keywordHumanspa
dc.subject.keywordInborn error of metabolismspa
dc.subject.keywordPhagocytosisspa
dc.subject.keywordPreeclampsiaspa
dc.subject.keywordPrevalencespa
dc.subject.keywordSignal transductionspa
dc.subject.keywordVascularizationspa
dc.subject.keywordWorld health organizationspa
dc.subject.keywordX chromosomespa
dc.subject.keywordCongenital hemolytic anemiaspa
dc.subject.keywordEpidemiologyspa
dc.subject.keywordErythrocytespa
dc.subject.keywordGeneticsspa
dc.subject.keywordGlucose-6-phosphate dehydrogenase deficiencyspa
dc.subject.keywordPhysiologyspa
dc.titleGlucose-6-phosphate dehydrogenase (G6PD). Response of the human erythrocyte and another cells to the decrease in their activityspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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