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Tamizaje neonatal para fibrosis quística en una muestra de la ciudad de Bogotá

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dc.contributor.advisorMateus Arbelaez, Heidi Eliana
dc.contributor.advisorFonseca Mendoza, Dora Janeth
dc.creatorAmado González, Paula
dc.creator.degreeMagíster en Ciencias con Énfasis en Genética Humana
dc.date.accessioned2012-07-19T12:29:20Z
dc.date.available2012-07-19T12:29:20Z
dc.date.created2011-12-15
dc.date.issued2011
dc.descriptionLa Fibrosis Quística es la enfermedad autosómica recesiva mas frecuente en caucásicos. En Colombia no se conoce la incidencia de la enfermedad, pero investigaciones del grupo de la Universidad del Rosario indican que podría ser relativamente alta. Objetivo: Determinar la incidencia de afectados por Fibrosis Quística en una muestra de recién nacidos de la ciudad de Bogotá. Metodología: Se analizan 8.297 muestras de sangre de cordón umbilical y se comparan tres protocolos de tamizaje neonatal: TIR/TIR, TIR/DNA y TIR/DNA/TIR. Resultados: El presente trabajo muestra una incidencia de 1 en 8.297 afectados en la muestra analizada. Conclusiones: Dada la relativamente alta incidencia demostrada en Bogotá, se justifica la implementación de Tamizaje Neonatal para Fibrosis Quística en Colombia.spa
dc.description.abstractCystic Fibrosis is the most common autosomic recessive disease in caucasic population. The incidence in Colombia is still unknown, but previous studies at Universidad del Rosario have shown that it is relatively high . Objective: To establish the incidence of the disease on a newborn population from Bogota. Methods: 8.297 cordblood samples were analyzed. Three neonatal screening test protocols were compared: IRT/IRT, IRT/DNA and IRT/DNA/IRT. Results: The present study showed an incidence of 1 in 8.297 for Cystic Fibrosis in the population. Conclusions: Given the relatively high incidence observed in Bogota, Cystic Fibrosis Neonatal screening is advisable for the colombian population.eng
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dc.format.tipoDocumentospa
dc.identifier.doihttps://doi.org/10.48713/10336_3616
dc.identifier.urihttp://repository.urosario.edu.co/handle/10336/3616
dc.language.isospa
dc.publisherUniversidad del Rosariospa
dc.publisher.departmentFacultad de medicinaspa
dc.publisher.programMaestría en Ciencias con Énfasis en Genética Humanaspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto completo)spa
dc.rights.ccAtribución-NoComercial-SinDerivadas 2.5 Colombiaspa
dc.rights.licenciaEL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma. PARÁGRAFO: En caso de presentarse cualquier reclamación o acción por parte de un tercero en cuanto a los derechos de autor sobre la obra en cuestión, EL AUTOR, asumirá toda la responsabilidad, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos la universidad actúa como un tercero de buena fe. EL AUTOR, autoriza a LA UNIVERSIDAD DEL ROSARIO, para que en los términos establecidos en la Ley 23 de 1982, Ley 44 de 1993, Decisión andina 351 de 1993, Decreto 460 de 1995 y demás normas generales sobre la materia, utilice y use la obra objeto de la presente autorización.spa
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dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subjectFibrosis quísticaspa
dc.subjectTamizaje neonatalspa
dc.subjectTripsinogenospa
dc.subjectSangre de cordón umbilicalspa
dc.subject.keywordCystic fibrosiseng
dc.subject.keywordNeonatal Screeningeng
dc.subject.keywordTripsinogeneng
dc.subject.keywordCord bloodeng
dc.subject.lembFibrosis quística::Investigacionesspa
dc.subject.lembExámenes médicos::Investigacionesspa
dc.subject.lembEnfermedades de los niños recién nacidos::Investigacionesspa
dc.titleTamizaje neonatal para fibrosis quística en una muestra de la ciudad de Bogotáspa
dc.typemasterThesiseng
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion
dc.type.spaTesis de maestríaspa
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Maestría en Genética Humana