Ítem
Solo Metadatos

Identifying and characterising the Plasmodium falciparum merozoite surface protein 10 Plasmodium vivax homologue

Mostrar el registro sencillo de la publicación
dc.creatorPérez-Leal, Óscarspa
dc.creatorSierra, Adriana Y.spa
dc.creatorBarrero, Carlos A.spa
dc.creatorMoncada, Camilospa
dc.creatorMartínez Rángel, Diana Pilarspa
dc.creatorCortés, Jimenaspa
dc.creatorLópez, Yolandaspa
dc.creatorSalazar, Luz M.spa
dc.creatorHoebekee, Johanspa
dc.creatorPatarroyo, Manuel A.spa
dc.date.accessioned2020-08-06T16:20:23Z
dc.date.available2020-08-06T16:20:23Z
dc.date.created2005-06-17spa
dc.description.abstractPlasmodium vivax malaria is one of the most prevalent parasitic diseases in Asia and Latin-America. The difficulty of maintaining this parasite culture in vitro has hampered identifying and characterising proteins implied in merozoite invasion of red blood cells. We have been able to identify an open reading frame in P. vivax encoding the Plasmodium falciparum merozoite surface protein 10 homologous protein using the partial sequences from this parasites genome reported during 2004. This new protein contains 479 amino-acids, two epidermal growth factor-like domains, hydrophobic regions at the N- and C-termini, being compatible with a signal peptide and a glycosylphosphatidylinositol anchor site, respectively. The protein is expressed during the parasites asexual stage and is recognised by polyclonal sera in parasite lysate using Western blot. P. vivax-infected patients sera highly recognised recombinant protein by ELISA.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.bbrc.2005.04.031
dc.identifier.issnISSN: 0006-291X
dc.identifier.issnEISSN: 1090-2104
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/25987
dc.language.isoengspa
dc.publisherElsevierspa
dc.relation.citationEndPage1184
dc.relation.citationIssueNo. 4
dc.relation.citationStartPage1178
dc.relation.citationTitleBiochemical and Biophysical Research Communications
dc.relation.citationVolumeVol. 331
dc.relation.ispartofBiochemical and Biophysical Research Communications, ISSN: 0006-291X;EISSN: 1090-2104, Vol.331, No.4 (2005); pp.1178-1184spa
dc.relation.urihttps://www.sciencedirect.com/science/article/abs/pii/S0006291X05007801spa
dc.rights.accesRightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.accesoRestringido (Acceso a grupos específicos)spa
dc.sourceBiochemical and Biophysical Research Communicationsspa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.keywordPlasmodium vivaxspa
dc.subject.keywordMalariaspa
dc.subject.keywordMSP10spa
dc.subject.keywordMerozoitespa
dc.subject.keywordVaccine candidatespa
dc.titleIdentifying and characterising the Plasmodium falciparum merozoite surface protein 10 Plasmodium vivax homologuespa
dc.title.TranslatedTitleIdentificación y caracterización de la proteína de superficie de merozoito Plasmodium falciparum 10 Homólogo de Plasmodium vivaxspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
Archivos
Colecciones
Artículos