Ítem
Acceso Abierto
Is primary hyperparathyroidism a pathogenic factor in some conditions mediated by B lymphocytes hyperactivity?
Título de la revista
Autores
Cañas, C.A.
Bonilla-Abadía, F.
Anaya, Juan-Manuel
Tobón, G.J.
Archivos
Fecha
2013
Directores
ISSN de la revista
Título del volumen
Editor
Buscar en:
Métricas alternativas
Resumen
Abstract
Several clinical cases have shown the association of primary hyperparathyroidism and immune conditions related to B-cell hyperactivity. In some of these cases the treatment of hyperparathyroidism led to the resolution of the autoimmune phenomena. Thus, this paper hypothesizes that high levels of parathyroid hormone (PTH) may modify B lymphocytes function and induce the development of autoimmunity mediated by B-cell hyperactivity. © 2013 Elsevier Ltd.
Palabras clave
Keywords
Interleukin 6 , primary , Parathyroid hormone , theoretical , Article , Autoimmunity , B lymphocyte , Disease association , Hematopoietic system , Hormone action , Human , Hypothesis , Interferon production , Kidney failure , Leukocyte disorder , Lymphocyte function , Parathyroidectomy , Primary hyperparathyroidism , B-lymphocytes , Humans , Hyperparathyroidism , Models , Parathyroid hormone
