Ítem
Solo Metadatos
An antibody profile of systemic lupus erythematosus detected by antigen microarray
Título de la revista
Autores
Fattal, Ittai
Shental, Noam
Mevorach, Dror
Anaya, Juan-Manuel
Livneh, Avi
Langevitz, Pnina
Zandman?Goddard, Gisele
Pauzner, Rachel
Lerner, Miriam
Blank, Miri
Fecha
2010-07
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Blackwell Publishing
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Resumen
Abstract
Patients with systemic lupus erythematosus (SLE) produce antibodies to many different self-antigens. Here, we investigated antibodies in SLE sera using an antigen microarray containing many hundreds of antigens, mostly self-antigens. The aim was to detect sets of antibody reactivities characteristic of SLE patients in each of various clinical states – SLE patients with acute lupus nephritis, SLE patients in renal remission, and SLE patients who had never had renal involvement
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Keywords
12E7 Antigen , Adult , Antibodies , Anticardiolipin , Antibodies , Antinuclear , Antigens , CD , Autoantibodies , Cell Adhesion Molecules , Collagen Type III , Down-Regulation , Female , Herpesvirus 4 , Human , Humans , Hyaluronic Acid , Immunoglobulin G , Immunoglobulin M , Insulin-Like Growth Factor Binding Protein 1 , Lupus Erythematosus , Systemic , Lupus Nephritis , Male , Middle Aged , Peroxidase , Protein Array Analysis , Sensitivity and Specificity , Up-Regulation
