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Letter to the Editor on Continuous Antibiotic Therapy Can Reduce Recurrence of Prosthetic Joint Infection in Patients Undergoing 2-Stage Exchange

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Autores
Castaño, Juliana
Moreno, Leonardo
Bautista, Maria
Suarez, Cristina
Bonilla, Guillermo

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Fecha
2019

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Editor
Churchill Livingstone Inc.
Elsevier

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Resumen
Abstract
We had the opportunity to read the article by Dr Ascione et al and we did it with great interest, as the authors address a relevant question regarding the treatment of periprosthetic joint infection, which has not been answered yet. We congratulate the authors for this initiative to determine which protocol of antibiotic treatment before reimplantation during 2-stage exchange leads to higher success rates [1]. However, the results and conclusions drawn from the study could be misleading, as there are some major methodological shortcomings that might jeopardize the validity of the results.
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Keywords
Antibiotic agent , Antibiotic therapy , Clinical outcome , Clinical protocol , Demography , Human , Letter , Periprosthetic joint infection , Practice guideline , Recurrent infection , Reimplantation , Statistical significance , Surgical technique , Treatment duration , Treatment response
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