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Autoimmune hepatitis - learning about your patients from their autoantibody profiles


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2011-12-07

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John Wiley & Sons

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Abstract
Autoimmune hepatitis (AIH) remains a disease without a diagnostic marker, and one that is as much an art to manage as is scientific discipline. As a broadly presenting clinical entity, AIH is a chronic and relapsing disease that nestles amongst a family of autoimmune liver diseases that likely share varying genetic risk, but have differing environmental triggers 1. In spite of the best efforts of Hepatologists to understand this apparently mixed group of hepatitic processes better, patients still undergo a series of investigations designed to exclude alternate better diagnoses, at which point, in the absence of a viral, metabolic or toxic insult, immunosuppression is initiated 2.
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Anti?La , Anti?Ro , Antisoluble liver antigen , Autoimmune hepatitis
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