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Granulomatosis con poliangeítis y compromiso en fosa posterior. Reporte de un caso

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Autores
Benavides Burbano, Camilo Armando
Vitola Dominguez, Alexander
Diaz Forero, Andres
Riveros Castillo, William Mauricio

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Fecha
2020-04-14

Directores
Riveros Castillo, William Mauricio

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Editor
Universidad del Rosario

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Resumen
Granulomatosis with Poliangeitis or Wegner's granulomatosis has an incidence of5-10 cases per million of habitants and only 2-11% of cases present manifestationsin the central nervous system. There are no standardized diagnostic criteria, however,clinical suspicion, positive serology for ANCA’S, histological evidence of necrotizingvasculitis, necrotizing glomerulonephritis or granulomatous inflammation of organssuch as skin, lung or kidney, may suggest this pathology. Neurosurgery is a diagnosticand therapeutic option and could be a possibility in those cases in which the lesionsare in accessible areas and have low risk of generating comorbidities. We presentthe case of a 39-year-old female patient with granulomatosis and polyangiitis withinvolvement in the posterior fossa. After surgical management, it presents meningealinfection. Additionally, we conducted a review of the pathology.
Abstract
Granulomatosis with Poliangeitis or Wegner's granulomatosis has an incidence of 5-10 cases per million of habitants and only 2-11% of cases present manifestations in the central nervous system. There are no standardized diagnostic criteria, however, clinical suspicion, positive serology for ANCA’S, histological evidence of necrotizing vasculitis, necrotizing glomerulonephritis or granulomatous inflammation of organs such as skin, lung or kidney, may suggest this pathology. Neurosurgery is a diagnostic and therapeutic option and could be a possibility in those cases in which the lesions are in accessible areas and have low risk of generating comorbidities. We present the case of a 39-year-old female patient with granulomatosis and polyangiitis with involvement in the posterior fossa. After surgical management, it presents meningeal infection. Additionally, we conducted a review of the pathology
Palabras clave
Granulomatosis with Polyangiitis , Wegener Granulomatosis , Antibodies Antineutrophil Cytoplasmic , Neurologic Manifestations , Neurosurgery
Keywords
Granulomatosis with Polyangiitis , Wegener Granulomatosis , Antibodies Antineutrophil Cytoplasmic , Neurologic Manifestations , Neurosurgery
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