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Autoimmune disease and gender: Plausible mechanisms for the female predominance of autoimmunity

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dc.creatorQuintero, Olga L.spa
dc.creatorAmador-Patarroyo, Manuel J.spa
dc.creatorMontoya-Ortiz, Gladysspa
dc.creatorRojas-Villarraga, Adrianaspa
dc.creatorAnaya, Juan-Manuelspa
dc.date.accessioned2020-05-25T23:55:53Z
dc.date.available2020-05-25T23:55:53Z
dc.date.created2012spa
dc.description.abstractA large number of autoimmune diseases (ADs) are more prevalent in women. The more frequent the AD and the later it appears, the more women are affected. Many ideas mainly based on hormonal and genetic factors that influence the autoimmune systems of females and males differently, have been proposed to explain this predominance. These hypotheses have gained credence mostly because many of these diseases appear or fluctuate when there are hormonal changes such as in late adolescence and pregnancy. Differences in X chromosome characteristics between men and women with an AD have led researchers to think that the genetic background of this group of diseases also relates to the genetic determinants of gender. These hormonal changes as well as the genetic factors that could explain why women are more prone to develop ADs are herein reviewed. © 2011 Elsevier Ltd.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.jaut.2011.10.003
dc.identifier.issn10959157
dc.identifier.issn08968411
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/22252
dc.language.isoengspa
dc.relation.citationEndPageJ119
dc.relation.citationIssueNo. 43892
dc.relation.citationStartPageJ109
dc.relation.citationTitleJournal of Autoimmunity
dc.relation.citationVolumeVol. 38
dc.relation.ispartofJournal of Autoimmunity, ISSN:10959157, 08968411, Vol.38, No.43892 (2012); pp. J109-J119spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84858752604&doi=10.1016%2fj.jaut.2011.10.003&partnerID=40&md5=4fc01085acc4c00466ee71ba1c29724dspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordAndrogenspa
dc.subject.keywordhumaneng
dc.subject.keywordBromocriptinespa
dc.subject.keywordEstrogenspa
dc.subject.keywordxeng
dc.subject.keywordEstrogen receptorspa
dc.subject.keywordProlactinspa
dc.subject.keywordAntibody productionspa
dc.subject.keywordArticlespa
dc.subject.keywordAutoimmune diseasespa
dc.subject.keywordAutoimmunityspa
dc.subject.keywordB lymphocyte activationspa
dc.subject.keywordCd4 lymphocyte countspa
dc.subject.keywordCd8+ t lymphocytespa
dc.subject.keywordCellular immunityspa
dc.subject.keywordDisease associationspa
dc.subject.keywordDisease predispositionspa
dc.subject.keywordGenetic riskspa
dc.subject.keywordHormonal regulationspa
dc.subject.keywordHumanspa
dc.subject.keywordHumoral immunityspa
dc.subject.keywordKlinefelter syndromespa
dc.subject.keywordLymphomaspa
dc.subject.keywordMicrochimerismspa
dc.subject.keywordMonocytespa
dc.subject.keywordMonosomy xspa
dc.subject.keywordMultiple sclerosisspa
dc.subject.keywordNatural killer cellspa
dc.subject.keywordNeutrophilspa
dc.subject.keywordOnset agespa
dc.subject.keywordPregnancyspa
dc.subject.keywordPregnancy outcomespa
dc.subject.keywordPrevalencespa
dc.subject.keywordPriority journalspa
dc.subject.keywordRaynaud phenomenonspa
dc.subject.keywordReceptor bindingspa
dc.subject.keywordRheumatoid arthritisspa
dc.subject.keywordSex differencespa
dc.subject.keywordSjoegren syndromespa
dc.subject.keywordSystemic lupus erythematosusspa
dc.subject.keywordSystemic sclerosisspa
dc.subject.keywordT lymphocyte activationspa
dc.subject.keywordTh1 cellspa
dc.subject.keywordTh2 cellspa
dc.subject.keywordX chromosomespa
dc.subject.keywordX chromosome inactivationspa
dc.subject.keywordY chromosomespa
dc.subject.keywordAutoimmune diseasesspa
dc.subject.keywordAutoimmunityspa
dc.subject.keywordChimerismspa
dc.subject.keywordChromosomeseng
dc.subject.keywordFemalespa
dc.subject.keywordHormonesspa
dc.subject.keywordHumansspa
dc.subject.keywordMalespa
dc.subject.keywordPregnancyspa
dc.subject.keywordSex factorsspa
dc.subject.keywordAutoimmune diseasesspa
dc.subject.keywordGender differencesspa
dc.subject.keywordSex hormonesspa
dc.subject.keywordX chromosomespa
dc.titleAutoimmune disease and gender: Plausible mechanisms for the female predominance of autoimmunityspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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