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Distribution patterns of infection with multiple types of human papillomaviruses and their association with risk factors
dc.audience | Comunidad Rosarista | spa |
dc.creator | Soto De Leon, Sara C | |
dc.creator | Camargo, Milena | |
dc.creator | Sánchez, Ricardo | |
dc.creator | Munoz, Marina | |
dc.creator | Perez-Prados, Antonio | |
dc.creator | Purroy, Antonio | |
dc.creator | Patarroyo, Manuel E. | |
dc.creator | Patarroyo, Manuel A. | |
dc.creator.google | Soto-De Leon, Sara | |
dc.creator.google | Camargo, Milena | |
dc.creator.google | Sanchez, Ricardo | |
dc.creator.google | Muñoz, Marina | |
dc.creator.google | Perez-Prados, Antonio | |
dc.creator.google | Purroy, Antonio | |
dc.creator.google | Patarroyo, Manuel Elkin | |
dc.creator.google | Patarroyo, Manuel Alfonso | |
dc.date.accessioned | 2014-08-13T19:41:08Z | |
dc.date.available | 2014-08-13T19:41:08Z | |
dc.date.created | 2011-02-17 | |
dc.date.issued | 2011 | |
dc.description.abstract | Background: Infection with multiple types of human papillomavirus (HPV) is one of the main risk factors associated with the development of cervical lesions. In this study, cervical samples collected from 1,810 women with diverse sociocultural backgrounds, who attended to their cervical screening program in different geographical regions of Colombia, were examined for the presence of cervical lesions and HPV by Papanicolau testing and DNA PCR detection, respectively. Principal Findings: The negative binomial distribution model used in this study showed differences between the observed and expected values within some risk factor categories analyzed. Particularly in the case of single infection and coinfection with more than 4 HPV types, observed frequencies were smaller than expected, while the number of women infected with 2 to 4 viral types were higher than expected. Data analysis according to a negative binomial regression showed an increase in the risk of acquiring more HPV types in women who were of indigenous ethnicity (+37.8%), while this risk decreased in women who had given birth more than 4 times (-31.1%), or were of mestizo (-24.6%) or black (-40.9%) ethnicity. Conclusions: According to a theoretical probability distribution, the observed number of women having either a single infection or more than 4 viral types was smaller than expected, while for those infected with 2-4 HPV types it was larger than expected. Taking into account that this study showed a higher HPV coinfection rate in the indigenous ethnicity, the role of underlying factors should be assessed in detail in future studies. | eng |
dc.format.medium | Recurso electrónico | spa |
dc.format.mimetype | application/pdf | |
dc.format.tipo | Documento | spa |
dc.identifier.doi | https://doi.org/10.1371/journal.pone.0014705 | |
dc.identifier.issn | 1932-6203 | |
dc.identifier.uri | http://repository.urosario.edu.co/handle/10336/8840 | |
dc.language.iso | eng | |
dc.publisher | Universidad del Rosario | spa |
dc.relation.citationIssue | No. 2 | |
dc.relation.citationTitle | PLOS ONE | |
dc.relation.citationVolume | Vol. 6 | |
dc.relation.ispartof | PLOS ONE ISSN: 1932-6203 V. 6 N. 2 Feb 17, 2011 | spa |
dc.relation.uri | http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0014705 | |
dc.rights.accesRights | info:eu-repo/semantics/openAccess | |
dc.rights.acceso | Abierto (Texto completo) | spa |
dc.rights.licencia | EL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma. | spa |
dc.source.instname | instname:Universidad del Rosario | spa |
dc.source.reponame | reponame:Repositorio Institucional EdocUR | spa |
dc.subject.ddc | Enfermedades | |
dc.subject.decs | Síndrome de Inmunodeficiencia Adquirida. SIDA | spa |
dc.subject.decs | Virus del papiloma humano. VPH | spa |
dc.subject.decs | Enfermedades infecciosas | spa |
dc.subject.decs | Enfermedades autoinmunes | spa |
dc.subject.keyword | Invasive carvical -cancer | eng |
dc.subject.keyword | HPV infection | eng |
dc.subject.keyword | Genetic susceptiblity | eng |
dc.subject.keyword | Unversity-students | eng |
dc.subject.keyword | African -american | eng |
dc.subject.keyword | PCR detection | eng |
dc.subject.keyword | Primer sets | eng |
dc.subject.keyword | Women | eng |
dc.subject.keyword | Epidemiology | eng |
dc.subject.keyword | Prevalence | eng |
dc.title | Distribution patterns of infection with multiple types of human papillomaviruses and their association with risk factors | spa |
dc.type | article | eng |
dc.type.hasVersion | info:eu-repo/semantics/acceptedVersion | |
dc.type.spa | Artículo | spa |
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