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Silicon, a possible link between environmental exposure and autoimmune diseases: The case of rheumatoid arthritis.

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dc.creatorSpeck-Hernandez, Cesar Aspa
dc.creatorMontoya-Ortiz, Gladisspa
dc.date.accessioned2020-08-06T16:20:28Z
dc.date.available2020-08-06T16:20:28Z
dc.date.created2012spa
dc.description.abstractSilicon is one of the most common chemicals on earth. Several compounds such as silica, asbestos, silicone or, nanoparticles are built from tetrahedral units with silicon as the central atom. Despite these, structural similarities, they have rarely been analyzed as a group. These compounds generate significant biological alterations that include immune hyperactivation, production of the reactive species of oxygen and tissue injury. These pathological processes may trigger autoimmune responses and lead to the development of rheumatoid arthritis. Populations at risk include those that constantly work in industrial process, mining, and agriculture as well as those that undergo silicone implants. Herein a review on the main features of these compounds and how they may induce autoimmune responses is presented.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1155/2012/604187
dc.identifier.issnISSN: 2090-1984
dc.identifier.issnEISSN: 2090-1992
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/26019
dc.language.isoengspa
dc.publisherHindawi Publishing Corporationspa
dc.relation.citationEndPage604187
dc.relation.citationStartPage604187
dc.relation.citationTitleArthritis
dc.relation.citationVolumeVol. 2012
dc.relation.ispartofArthritis, ISSN: 2090-1984 ; EISSN: 2090-1992, Vol.2012 (2012); pp.604187-604187spa
dc.relation.urihttp://downloads.hindawi.com/archive/2012/604187.pdfspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.sourceArthritisspa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.keywordsilicaspa
dc.subject.keywordasbestosspa
dc.subject.keywordsiliconespa
dc.subject.keywordbiological alterationsspa
dc.subject.keywordoxygenspa
dc.subject.keywordtissue injuryspa
dc.titleSilicon, a possible link between environmental exposure and autoimmune diseases: The case of rheumatoid arthritis.spa
dc.title.TranslatedTitleEl silicio, un posible vínculo entre la exposición ambiental y las enfermedades autoinmunes: el caso de la artritis reumatoide.spa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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