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Reacciones adversas secundarias a opioides parenterales para manejo de dolor agudo en población anciana: Revisión ampliada de la literatura

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dc.contributor.advisorBarragán González, Ana María
dc.contributor.advisorLa Rota Hernández, Jaime Fernando
dc.creatorPabón Londoño, Santiago
dc.creatorCueto Butrón, Gina Vanessa
dc.creator.degreeEspecialista en Toxicología Clínicaspa
dc.creator.degreetypeFull timespa
dc.date.accessioned2021-07-27T00:20:19Z
dc.date.available2021-07-27T00:20:19Z
dc.date.created2021-06-23
dc.descriptionEn la literatura es escaza la caracterización de los efectos adversos relacionados con opioides endovenosos para dolor agudo en la población anciana. Objetivo: Mapear la evidencia de efectos adversos relacionados con opioides parenterales para dolor agudo en pacientes ancianos. Metodología: Revisión ampliada de la literatura. Los componentes de la pregunta de investigación fueron: pacientes igual o mayores a 65 años de edad, descripción o análisis de efectos adversos de opioides administrados por vía parenteral. Se tuvieron en cuenta variables relacionadas con el dolor. Se identificaron los desenlaces asociados al efecto adverso, el análisis o no de interacciones farmacológicas y variables sociodemográficas como la raza, el estrato social, el acceso de red de apoyo y el antecedente de uso de opioides. Se realizó la búsqueda en base de datos PUBMED, COCHRANE, EMBASE, Scopus y en literatura gris, sin ninguna restricción de idioma. Resultados: Se obtuvieron 35 estudios. El país que mas reporto fue Estados Unido (40%). El opioides mas frecuentemente formulado fue fenatnilo en el 42% de los estudios (n=15). El efecto adverso mas frecuentemente encontrado fueron los relacionados con el tracto gastrointestinal en 37% de los artículos. Las comorbilidades mas asociada fueron de tipo cardiovascular. El 5.71% (n=2) reportó el estrato sociodemográfico de los pacientes. Conclusión: Se presentó una descripción de la cantidad, tipos de estudios, desenlaces, tipo de población, alrededor de efectos adversos relacionados con opioides parenterales para dolor agudo en pacientes de 65 años o mas.spa
dc.description.abstractBackground: Characterization of adverse effects related to intravenous opioids for acute pain in the elderly population is sparse in the literature. Objective: To map the evidence of adverse effects related to parenteral opioids for acute pain in elderly patients. Methodology: Scooping review of literature. The components of the research question were patients equal to or older than 65 years of age, description or analysis of adverse effects of parenterally administered opioids. Pain-related variables were taken into account. The outcomes associated with the adverse effect, the analysis or not of pharmacological interactions and sociodemographic variables such as race, social stratum, access to support network and history of opioid use were identified. We searched PUBMED, COCHRANE, EMBASE, Scopus and gray literature databases, without any language restriction. Results: Thirty-five studies were obtained. The country that reported the most was the United States (40%). The most frequently formulated opioid was phenatnyl in 42% of the studies (n=15). The most frequently encountered adverse effect were those related to the gastrointestinal tract in 37% of the articles. The most frequently associated comorbidities were cardiovascular. The sociodemographic stratum of the patients was reported in 5.71% (n=2). Conclusion: A description of the number, types of studies, outcomes, type of population, and adverse effects related to parenteral opioids for acute pain in patients aged 65 years or older was presented.spa
dc.format.extent44 pp.spa
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.48713/10336_31921
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/31921
dc.language.isospaspa
dc.publisherUniversidad del Rosario
dc.publisher.departmentEscuela de Medicina y Ciencias de la Salud
dc.publisher.programToxicología Clínica
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
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dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subjectEfecto adverso en el uso de opioides en el tratamiento del dolorspa
dc.subjectFrecuencia de presentación de efectos secundarios frente a la administración de opioides endovenososspa
dc.subjectAnálisis de los efecto secundario en el tratamiento del dolor agudo con opioides en ancianosspa
dc.subject.ddcFarmacología & terapéuticaspa
dc.subject.keywordAdverse effect in the use of opioids in the treatment of painspa
dc.subject.keywordFrequency of presentation of side effects compared to the administration of intravenous opioidsspa
dc.subject.keywordAnalysis of side effects in the treatment of acute pain with opioids in the elderlyspa
dc.titleReacciones adversas secundarias a opioides parenterales para manejo de dolor agudo en población anciana: Revisión ampliada de la literaturaspa
dc.title.TranslatedTitleParenteral Opioid-related Adverse Effects for acute pain in elderly population: Scooping Review of the literaturespa
dc.typemasterThesiseng
dc.type.documentRevisión de la literaturaspa
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion
dc.type.spaTrabajo de gradospa
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