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The effect of exercise training on mediators of inflammation in breast cancer survivors: a systematic review with metaanalysis: 1883 Board #35 June 2, 330 PM - 500 PM

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dc.creatorRamírez-Vélez, Robinsonspa
dc.creatorMeneses-Echávez, Josespa
dc.creatorCorrea Bautista, Jorge Enrique
dc.creatorSabogal, Estebanspa
dc.creatorMartínez-Torres, Javierspa
dc.creatorGonzález-Ruíz, Katherinespa
dc.date.accessioned2020-08-06T16:24:07Z
dc.date.available2020-08-06T16:24:07Z
dc.date.created2016-05spa
dc.description.abstractPURPOSE: Several evidences have proposed that exercise during and after breast cancer could positively modulate the tumor microenvironment. This metaanalysis aimed to determine the effects of exercise training on mediators of inflammation in breast cancer survivors. METHODS: We searched for randomized controlled trials published from January 1990 to March 2014. An inverse variance method of metaanalysis was performed using a random effects model in the presence of statistical heterogeneity (I2 > 50%). RESULTS: Eight highquality trials (n = 478) were included. Exercise improved the serum concentrations of IL6 (Weighted mean difference (WMD) = 0.55 pg/mL, (95% CI 1.02 to 0.09), TNF? (WMD= 0.64 pg/mL, 95% CI 1.21 to 0.06), IL8 (MD = 0.49 pg/mL, 95% CI 0.89 to 0.09), IL2 (WMD= 1.03 pg/mL, 95% CI 0.40 to 1.67). Conversely, no significant differences were found in the serum concentrations of C reactive protein (CRP) (WMD= 0.15, 95% CI 0.56 to 0.25) or IL10 (WMD= 0.41, 95% CI 0.18 to 1.02). CONCLUSIONS: Exercise training positively modulates chronic low grade inflammation in women with breast cancer, which may impact upon carcinogenic mechanisms and the tumor microenvironment. These findings align with the other positive effects of exercise for breast cancer survivors, reinforcing the appropriateness of exercise prescription in this population.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1249/01.mss.0000486556.69698.52
dc.identifier.issnISSN: 0195-9131
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/26469
dc.language.isoengspa
dc.publisherAmerican College of Sports Medicinespa
dc.publisherOvid Technologiesspa
dc.relation.citationIssueNo. 5S
dc.relation.citationStartPage517
dc.relation.citationTitleMedicine & Science in Sports & Exercise
dc.relation.citationVolumeVol. 48
dc.relation.ispartofMedicine & Science in Sports & Exercise, ISSN: 0195-9131, Vol.48, No.5S (May 2016); pp.517spa
dc.relation.ispartofD-24 Free Communication/Poster - Cancer Thursday, June 2, 2016, 1: 00 Pm - 6: 00 Pm Room: Exhibit Hall A/Bspa
dc.relation.urihttps://journals.lww.com/acsm-msse/Fulltext/2016/05001/The_Effect_Of_Exercise_Training_On_Mediators_Of.1550.aspxspa
dc.rights.accesRightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.accesoRestringido (Acceso a grupos específicos)spa
dc.sourceMedicine & Science in Sports & Exercisespa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.keywordExercise trainingspa
dc.subject.keywordCancerspa
dc.subject.keywordMedical and Health Sciencesspa
dc.subject.keywordMedical Physiologyspa
dc.subject.keywordPublic Health and Health Servicesspa
dc.titleThe effect of exercise training on mediators of inflammation in breast cancer survivors: a systematic review with metaanalysis: 1883 Board #35 June 2, 330 PM - 500 PMspa
dc.title.TranslatedTitleEl efecto del entrenamiento con ejercicios sobre los mediadores de la inflamación en sobrevivientes de cáncer de mama: una revisión sistemática con metaanálisis: 1883 Board # 35 2 de junio, 330 PM - 500 PMspa
dc.typeconferenceObjecteng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaDocumento de conferenciaspa
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