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dc.contributor.advisorGarcés Sterling, Sandra Patricia 
dc.contributor.advisorMorón Duarte, Lina Sofía 
dc.creatorUreña Guerrero, Maira Alejandra 
dc.creatorVargas Lara, Diana 
dc.date.accessioned2016-03-07T15:15:42Z
dc.date.available2016-03-07T15:15:42Z
dc.date.created2015-12-07
dc.date.issued2015 
dc.identifier.urihttp://repository.urosario.edu.co/handle/10336/11780
dc.descriptionLa trombosis relacionada al uso del catéter es un problema que cobra cada vez mayor importancia. Se han descrito factores de riesgo para su presentación en la población pediátrica pero aún no se han realizado estudios en nuestro medio. Objetivo: Determinar los factores de riesgo y la prevalencia de la trombosis asociada a catéter venoso central en los pacientes pediátricos de la Fundación Cardioinfantil hospitalizados durante el periodo comprendido entre Julio 2013 a Julio 2015. Metodología: Se realizó un estudio de corte transversal de asociación. Se incluyeron pacientes clasificados en 4 grupos: trombosis y catéter, trombosis sin catéter, catéter sin trombosis y sin trombosis ni catéter. Se estimaron OR como medidas de asociación utilizando el estadístico mantel haenszel. Resultados: En total se incluyeron 221 pacientes. La prevalencia de la trombosis y uso del catéter fue del 22%. La edad inferior a los 36 meses (OR 2,27 IC95% 1,16-4,44,p<0.001), profilaxis antitrombótica (OR 34,4 IC95% 4,18-282,92, p<0.01), hospitalización en la UCI (OR 3,82, IC95% 1,69-8,65, p<0.001) y el tiempo de hospitalización (OR 16,83 IC95% 7,8-36,27, p<0.001) están asociadas con un mayor riesgo de presentación de la trombosis. Conclusión: La edad, hospitalización en UCI, uso de profilaxis antitrombótica y el tiempo de hospitalización son factores de riesgo que estan relacionados con la presentación de la trombosis en pacientes con cateter.
dc.description.abstractThrombosis related to catheter use is a problem that is becoming increasingly important. The risk factors for presentation in the pediatric population has been described but no studies have been conducted in our country. Objective: To determine the risk factors and prevalence of thrombosis associated with central venous catheters in pediatric patients hospitalized Cardioinfantil Foundation for the period from July 2013 to July 2015. Methodology: An association cross-sectional study was conducted. Thrombosis and catheter thrombosis without catheter without catheter thrombosis without thrombosis and catheter: patients classified into 4 groups were included. OR they were estimated as measures of association using the statistical mantel-haenszel. Results: In total 221 patients were included. The prevalence of thrombosis and catheter use was 22%. Age less than 36 months (OR 2.27 95% CI 1.16 to 4.44, p <0.001) antithrombotic prophylaxis (OR 34.4 95% CI 4.18 to 282.92, P <0.01), hospitalization ICU (OR 3.82, 95% CI 1.69 to 8.65, p <0.001) and hospitalization time (95% CI 7.8 to 36.27 OR 16.83, p <0.001) are associated with presenting a higher risk of thrombosis. Conclusion: Age, ICU hospitalization, use of antithrombotic prophylaxis and hospitalization time are risk factors that are related to the presentation of thrombosis in patients with catheter.
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dc.language.isospa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/co/
dc.sourceinstname:Universidad del Rosario
dc.sourcereponame:Repositorio Institucional EdocUR
dc.subjectTrombosis
dc.subjectCatéter
dc.subjectCatéter venoso central
dc.subjectniños
dc.subject.ddcGinecología & otras especialidades médicas 
dc.subject.lembPediatría
dc.titleTrombosis asociada a cateter venoso central en pediatría de la Fundación Cardioinfantil julio 2013 a julio 2015
dc.typemasterThesis
dc.publisherUniversidad del Rosario
dc.creator.degreeEspecialista en Pediatría
dc.publisher.programEspecialización en Pediatría
dc.publisher.departmentFacultad de medicina
dc.subject.keywordThrombosis
dc.subject.keywordCatheter
dc.subject.keywordCentral venous catheter
dc.subject.keywordChildren
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.subject.decsPediatría
dc.subject.decsTrombosis
dc.subject.decsEnfermedades de las arterias
dc.type.spaTrabajo de grado
dc.rights.accesoAbierto (Texto completo)
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion
dc.source.bibliographicCitationSpentzouris G, Scriven RJ, Lee TK, Labropoulos N. Pediatric venous thromboembolism in relation to adults. J Vasc Surg. 2012;55(6):1785-93
dc.source.bibliographicCitationSandoval JA, Sheehan MP, Stonerock CE, Shafique S, Rescorla FJ, Dalsing MC. Incidence, risk factors, and treatment patterns for deep venous thrombosis in hospitalized children: an increasing population at risk. J Vasc Surg. 2008;47(4):837-43
dc.source.bibliographicCitationBoulet SL, Grosse SD, Thornburg CD, Yusuf H, Tsai J, Hooper WC. Trends in venous thromboembolism-related hospitalizations, 1994-2009. Pediatrics. 2012;130(4):e812-20
dc.source.bibliographicCitationChan AK, Monagle P. Updates in thrombosis in pediatrics: where are we after 20 years? Hematology Am Soc Hematol Educ Program. 2012;2012:439-43
dc.source.bibliographicCitationTolbert J, Carpenter SL. Common acquired causes of thrombosis in children. Curr Probl Pediatr Adolesc Health Care. 2013;43(7):169-77
dc.source.bibliographicCitationRaffini L, Huang YS, Witmer C, Feudtner C. Dramatic increase in venous thromboembolism in children's hospitals in the United States from 2001 to 2007. Pediatrics. 2009;124(4):1001-8
dc.source.bibliographicCitationAndrew M, David M, Adams M, Ali K, Anderson R, Barnard D, et al. Venous thromboembolic complications (VTE) in children: first analyses of the Canadian Registry of VTE. Blood. 1994;83(5):1251-7
dc.source.bibliographicCitationNowak-Göttl U, Janssen V, Manner D, Kenet G. Venous thromboembolism in neonates and children--update 2013. Thromb Res. 2013;131 Suppl 1:S39-41
dc.source.bibliographicCitationSamková A, Lejhancová K, Hak J, Lukes A. Venous thromboembolism in adolescents. Acta Medica (Hradec Kralove). 2012;55(2):78-82
dc.source.bibliographicCitationKenet G, Nowak-Göttl U. Venous thromboembolism in neonates and children. Best Pract Res Clin Haematol. 2012;25(3):333-44
dc.source.bibliographicCitationChalmers EA. Epidemiology of venous thromboembolism in neonates and children. Thromb Res. 2006;118(1):3-12
dc.source.bibliographicCitationWright JM, Watts RG. Venous thromboembolism in pediatric patients: epidemiologic data from a pediatric tertiary care center in Alabama. J Pediatr Hematol Oncol. 2011;33(4):261-4
dc.source.bibliographicCitationMassicotte MP, Sofronas M, deVeber G. Difficulties in performing clinical trials of antithrombotic therapy in neonates and children. Thromb Res. 2006;118(1):153-63
dc.source.bibliographicCitationWolberg AS, Aleman MM, Leiderman K, Machlus KR. Procoagulant activity in hemostasis and thrombosis: Virchow's triad revisited. Anesth Analg. 2012;114(2):275-85
dc.source.bibliographicCitationFurie B, Furie BC. Mechanisms of thrombus formation. N Engl J Med. 2008;359(9):938-49
dc.source.bibliographicCitationHoffman M. Remodeling the blood coagulation cascade. J Thromb Thrombolysis. 2003;16(1-2):17-20
dc.source.bibliographicCitationMann KG, Brummel-Ziedins K, Orfeo T, Butenas S. Models of blood coagulation. Blood Cells Mol Dis. 2006;36(2):108-17
dc.source.bibliographicCitationHoffman M. A cell-based model of coagulation and the role of factor VIIa. Blood Rev. 2003;17 Suppl 1:S1-5
dc.source.bibliographicCitationButenas S, Orfeo T, Mann KG. Tissue factor activity and function in blood coagulation. Thromb Res. 2008;122 Suppl 1:S42-6
dc.source.bibliographicCitationRoth M, Manwani D. Thrombotic disorders. Pediatr Rev. 2011;32(1):41-3
dc.source.bibliographicCitationRevel-Vilk S, Kenet G. Thrombophilia in children with venous thromboembolic disease. Thromb Res. 2006;118(1):59-65
dc.source.bibliographicCitationZöller B, García de Frutos P, Hillarp A, Dahlbäck B. Thrombophilia as a multigenic disease. Haematologica. 1999;84(1):59-70
dc.source.bibliographicCitationRaffini L, Thornburg C. Testing children for inherited thrombophilia: more questions than answers. Br J Haematol. 2009;147(3):277-88
dc.source.bibliographicCitationRevel-Vilk S, Chan A, Bauman M, Massicotte P. Prothrombotic conditions in an unselected cohort of children with venous thromboembolic disease. J Thromb Haemost. 2003;1(5):915-21
dc.source.bibliographicCitationJourneycake JM, Buchanan GR. Coagulation disorders. Pediatr Rev. 2003;24(3):83-91
dc.source.bibliographicCitationGoldenberg NA. Thrombophilia states and markers of coagulation activation in the prediction of pediatric venous thromboembolic outcomes: a comparative analysis with respect to adult evidence. Hematology Am Soc Hematol Educ Program. 2008:236-44
dc.source.bibliographicCitationBrandao LR, Segel GB. Question from the clinician: risk of thrombophilia. Pediatr Rev. 2012;33(7):321-2
dc.source.bibliographicCitationTakemoto CM, Sohi S, Desai K, Bharaj R, Khanna A, McFarland S, et al. Hospital-associated venous thromboembolism in children: incidence and clinical characteristics. J Pediatr. 2014;164(2):332-8
dc.source.bibliographicCitationHanslik A, Thom K, Haumer M, Kitzmüller E, Albinni S, Wolfsberger M, et al. Incidence and diagnosis of thrombosis in children with short-term central venous lines of the upper venous system. Pediatrics. 2008;122(6):1284-91
dc.source.bibliographicCitationKanin M, Young G. Incidence of thrombosis in children with tunneled central venous access devices versus peripherally inserted central catheters (PICCs). Thromb Res. 2013;132(5):527-30
dc.source.bibliographicCitationPiovesan D, Attard C, Monagle P, Ignjatovic V. Epidemiology of venous thrombosis in children with cancer. Thromb Haemost. 2014;111(6):1015-21
dc.source.bibliographicCitationFalanga A, Marchetti M. Anticancer treatment and thrombosis. Thromb Res. 2012;129(3):353-9
dc.source.bibliographicCitationDe Stefano V, Za T, Ciminello A, Betti S, Rossi E. Haemostatic alterations induced by treatment with asparaginases and clinical consequences. Thromb Haemost. 2014;113(2)
dc.source.bibliographicCitationKim SJ, Sabharwal S. Risk factors for venous thromboembolism in hospitalized children and adolescents: a systemic review and pooled analysis. J Pediatr Orthop B. 2014;23(4):389-93
dc.source.bibliographicCitationStokes S, Breheny P, Radulescu A, Radulescu VC. Impact of obesity on the risk of venous thromboembolism in an inpatient pediatric population. Pediatr Hematol Oncol. 2014;31(5):475-80
dc.source.bibliographicCitationBranchford BR, Mourani P, Bajaj L, Manco-Johnson M, Wang M, Goldenberg NA. Risk factors for in-hospital venous thromboembolism in children: a case-control study employing diagnostic validation. Haematologica. 2012;97(4):509-15
dc.source.bibliographicCitationSharathkumar AA, Mahajerin A, Heidt L, Doerfer K, Heiny M, Vik T, et al. Risk-prediction tool for identifying hospitalized children with a predisposition for development of venous thromboembolism: Peds-Clot clinical Decision Rule. J Thromb Haemost. 2012;10(7):1326-34
dc.source.bibliographicCitationAtchison CM, Arlikar S, Amankwah E, Ayala I, Barrett L, Branchford BR, et al. Development of a new risk score for hospital-associated venous thromboembolism in noncritically ill children: findings from a large single-institutional case-control study. J Pediatr. 2014;165(4):793-8
dc.source.bibliographicCitationYang JY, Chan AK. Pediatric thrombophilia. Pediatr Clin North Am. 2013;60(6):1443-62
dc.source.bibliographicCitationMonagle P, Chan AK, Goldenberg NA, Ichord RN, Journeycake JM, Nowak-Göttl U, et al. Antithrombotic therapy in neonates and children: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012;141(2 Suppl):e737S-801S
dc.source.bibliographicCitationFaustino EV, Spinella PC, Li S, Pinto MG, Stoltz P, Tala J, et al. Incidence and acute complications of asymptomatic central venous catheter-related deep venous thrombosis in critically ill children. J Pediatr. 2013;162(2):387-91
dc.source.bibliographicCitationLi S, Sun X, Wang Z. Observation of short-term catheter induced thrombosis in children treated with blood purification. Hippokratia. 2014; 18 (3): 245-50
dc.source.bibliographicCitationSol JJ, Knoester H, de Neef M, Smets AM, Betlem A, van Ommen CH. Chronic Complications After Femoral Central Venous Catheter-related Thrombosis in Critically Ill Children. J Pediatr Hematol Oncol 2015; 37 (6): 462-7
dc.source.bibliographicCitationJumani K, Advani S, Reich NG, Gosey L, Milstone AM. Risk factors for peripherally inserted central venous catheter complications in children. JAMA Pediatr. 2013; 167 (5): 429-35
dc.source.bibliographicCitationSmitherman AB, Alexander T, Connelly M, Snavely AC, Weston BW, Liles EA, Steiner MJ. The incidence of catheter-associated venous thrombosis in noncritically ill children. Hosp Pediatr. 2015; 5 (2): 59-66
dc.source.bibliographicCitationReiter PD, Wathen B, Valuck RJ, Dobyns EL. Pediatr Crit Care Med 2012; 13 (4): 381-6
dc.rights.ccAtribución-NoComercial-SinDerivadas 2.5 Colombia
dc.rights.licenciaEL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma. PARGRAFO: En caso de presentarse cualquier reclamación o acción por parte de un tercero en cuanto a los derechos de autor sobre la obra en cuestión, EL AUTOR, asumirá toda la responsabilidad, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos la universidad actúa como un tercero de buena fe. EL AUTOR, autoriza a LA UNIVERSIDAD DEL ROSARIO, para que en los términos establecidos en la Ley 23 de 1982, Ley 44 de 1993, Decisión andina 351 de 1993, Decreto 460 de 1995 y demás normas generales sobre la materia, utilice y use la obra objeto de la presente autorización. -------------------------------------- POLITICA DE TRATAMIENTO DE DATOS PERSONALES. Declaro que autorizo previa y de forma informada el tratamiento de mis datos personales por parte de LA UNIVERSIDAD DEL ROSARIO para fines académicos y en aplicación de convenios con terceros o servicios conexos con actividades propias de la academia, con estricto cumplimiento de los principios de ley. Para el correcto ejercicio de mi derecho de habeas data cuento con la cuenta de correo habeasdata@urosario.edu.co, donde previa identificación podré solicitar la consulta, corrección y supresión de mis datos.


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