High muscular fitness has a powerful protective cardiometabolic effect: influence of weight status 831 Board #147 June 1, 2:00 PM - 3:30 PM

Abstract

PURPOSE: Low levels of muscular fitness (MF), measured using a hand dynamometer, is recognised as an important marker of nutritional status and a predictor of metabolic complications, cardiovascular disease and death. However, to date the relationship between MF, body mass index and the subsequent cardiometabolic protective effect has been studied very little among the population of Latin America. The purpose of the present study is to identify the association between the cardiometabolic risk score index (CMRSI) and the lipid-metabolic cardiovascular risk index (LMCRI) and MF in a wide sample of young university students grouped according to their body mass index (BMI). METHODS: A total of 6,095 healthy males with a mean age of 29.6 ± 11.7 years participated in the study. Their absolute strength was measured using a T.K.K analogue dynamometer (handgrip) and their strength relative to their body mass (MF/BM) was then calculated. The LMCRI was derived from the levels of triglycerides, low-density lipoprotein cholesterol (LDL-c), high-density lipoprotein cholesterol (HDL-c), and glucose levels. The CMRSI was calculated by summing standardised residuals (z-score) for waist circumference, total cholesterol, LDL-c, trygicerides, HDL-c, and median blood pressure. Subjects were divided into six subgroups according to BMI (normal vs. overweight/obese) and MF (Tertiles: unfit, average, fit). RESULTS: The group of participants with low and moderate levels of FM/BM, independent of BMI, showed higher CMRSI values (P < .001). The group with normal BMI and high FM/MB showed the highest level of cardiometabolic protection. For the LMCRI values, all groups with overweight/obese BMI showed significantly higher risk, independent of the level of MF/BM (P < .001). CONCLUSIONS: Our results show that participants with high MF/BM showed reduced cardiometabolic risk, which increased significantly when the BMI values were within normal parameters.