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Intraclass correlation between echocardiographic findings and hemodynamic data in patients diagnosed with idiopathic pulmonary hypertension in Fundacion Cardioinfantil – Instituto de cardiologia in Bogota Colombia
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Huertas Quiñones, Victor Manuel
Stapper Ortega, Claudia Maritza
García Torres, Alberto
Ronderos Dumit, Miguel
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2017-07
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Cambridge University Press
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Abstract
Objectives: Pulmonary hypertension (PH) is defined as a mean pulmonary arterial pressure ? 25 mmHg. The diagnosis of idiopathic PH is made after a thorough study clinical and paraclinical including complete anatomical and functional assessment. The aim of this study is to describe echocardiographic findings and hemodynamic data obtained by cardiac catheterization and assess their degree of correlation. Materials and Methods: Descriptive cross-sectional study and analysis of matching variables through the comparison of pulmonary pressure measured by echocardiography and catheterization through Interclase correlation coefficient (ICC) and the Bland Altman. The study population were children aged 0 days to 18 years who presented Fundación Cardioinfantil – Instituto de Cardiología in Bogotá (Colombia) diagnosed with idiopathic PH evaluated between January 2010 and December 2013. Results: 29 patients diagnosed with idiopathic PH studied with echocardiography and cardiac catheterization were included. The degree of PH documented by echocardiography corresponded to severe in 38% of patients. After cardiac catheterization, the degree of PH was classified as severe in 66% of cases. In 18 patients (62%) pulmonary vascular reactivity test was performed, finding positive response in 7 cases (39%). The concordance analysis of pulmonary pressure measured by echocardiography and catheterization was performed in 20 subjects, with a confidence level of 95%. When comparing the measurement results in both tests is a difference of 15 mmHg which is statistically significant. The tests achieved an ICC of 0.55, with 95% of 0.16 to 0.79, which represents a force of moderate agreement. Conclusions: In the present study the severity of PH corresponded to severe in most patients evaluated for cardiac catheterization. Performing pulmonary vascular reactivity test for both diagnosis and accurate diagnostic decisions is essential. The concordance analysis of pulmonary pressure measured by echocardiography and catheterization through Intraclase Correlation coefficient and the Bland Altman documents a force of moderate agreement
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Cardiorespiratory Medicine and Haematology , Medical and Health Sciences
