Prevalence of metabolic syndrome in colombian children and adolescents aged 9-17 years using three different pediatric definitions: 3188 Board #253 June 3, 200 PM - 330 PM
Zamudio, Jose Alejandro Anzola
Ojeda-Pardo, Monica Liliana
Correa-Bautista, Jorge Enrique
"PURPOSE: Currently, there is no gold standard definition for Metabolic syndrome (MetS) in children and adolescents; however, the description of prevalence of MetS according to few proposed pediatric definitions is necessary in Latin American populations. The objective of this study was to assess the prevalence of MetS in children and adolescents aged 9-17 years from Bogotá, Colombia using three different definitions for this age group. METHODS: The sample (n=1,939) consisted of 879 male and 1,060 female children and adolescents aged 9-17 years from a cross-sectional population survey, the FUPRECOL Study. Study information sheets were provided to participants and informed written consent was obtained from both the parent and the child. MetS was estimated according to the definitions by Cook et al., de Ferranti et al. and IDF, which use age-adjusted cut-off points. Blood was collected via capillary sample following an overnight fast. Fasting glucose, high-density lipoprotein cholesterol (HDL-C) and triglycerides (TAG) were determined using commercial kits in an automatic analyzer (Cardiocheck Inc., USA). Waist circumference (WC), Body mass index (BMI) and blood pressure measurements were made by trained investigators using standard techniques and instruments. RESULTS: On comparing our prevalence of MetS according to the definitions by Cook et al. and de Ferranti et al. with that in the original studies, our prevalence was lower than that reported in the study by Cook et al. (3.2% vs. 4.2%), and almost comparable with that presented in the study by de Ferranti et al. (13.2% vs. 9.2%). The most frequent combination of the MetS components was low HDL-C, abdominal obesity and elevated blood pressure, followed by low HDL-C, high serum TAG and elevated blood pressure. CONCLUSIONS: Primordial prevention of CVD should start in the pediatric years. Further research is required for the evaluation of the current definitions (multicentric studies), addition or design of new and useful criteria, and, importantly, analysis of the predictive capabilities of the pediatric MetS definitions for cardiometabolic diseases during adult life periods."
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