Vogt-Koyanagi-Harada syndrome in a group of patients in two ophthalmology referral centers in Bogotá, Colombia.: VKH syndrome in Colombia

Abstract

Purpose: To describe the clinical presentation of Vogt–Koyanagi–Harada (VKH) syndrome in a group of patients in Colombia. Methods: Retrospective review of 2638 medical records of patients with uveitis in two centers during 17 years. Results: A total of 25 patients with uveitis were diagnosed with VKH syndrome (0.95%), 23 patients were included in the data analysis (0.87%), 78.3% females, and mean age of diagnosis was 37 years (SD ± 29). Main complaints: blurred vision (87%), headaches (47.8%), tinnitus (26.1%), and hearing impairments (21.7%). Ophthalmic findings: bilateral serous retinal detachment (73.9%) and non-granulomatous uveitis (52.3%). Most of the patients were diagnosed with probable disease (56.5%). Mean duration of follow-up was 14 months; disease relapse was encountered in 26% of patients despite treatment. Conclusion: Patients in Colombia with VKH had clinical features similar to those reported in other Hispanic populations, except for the non-granulomatous uveitis. This disease may be considered as having variation of clinical manifestations across population groups.