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Manifestaciones clínicas y radiológicas de los pacientes con tuberculosis con y sin diabetes mellitus

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dc.contributor.advisorLutz, Juan Ricardo
dc.creatorBotero Ospina, María Helena
dc.creatorEspinosa, Juan Sebastian
dc.creator.degreeEspecialista en Medicina Interna
dc.date.accessioned2018-02-06T19:33:23Z
dc.date.available2018-02-06T19:33:23Z
dc.date.created2018-01-11
dc.date.issued2018
dc.descriptionIntroducción: Los pacientes con diagnóstico de tuberculosis (TB) y diabetes mellitus (DM) pueden tener una evolución clínica diferente a los pacientes sin DM. Sin embargo, aún persiste la incertidumbre acerca de esta relación. Objetivo: Describir y comparar, los hallazgos clínico radiológico, en los pacientes que cursan con Tuberculosis, con y sin diabetes mellitus en el hospital universitario mayor. Métodos: Estudio de corte transversal del universo de pacientes con diagnóstico de TB manejados en la institución. Se recolectó información de datos sociodemográficos, clínicos, paraclínicos y de desenlace de pacientes atendidos durante cinco años (2012 a 2016). Se utilizó estadística descriptiva univariada y luego bivariada para presentar la distribución de las características de los pacientes por presencia o no de DM. Se exploró la existencia de diferencias entre los pacientes diabéticos controlados versus no controlados (Se definió como paciente controlado hemoglobina glicosilada <7%.), calculando razones de prevalencia de variables relevantes. Resultados: Se incluyeron 221 pacientes con TB, de los cuales 32 tenían DM (14,48%). Mediana de edad 66 años (Q1 48 ; Q3 76). Los pacientes con TB/DM fueron de mayores en edad, con mayor prevalencia de hipertensión arterial y enfermedad renal crónica (p=0.005). Dentro de los pacientes con DM los no controlados presentaron mayor prevalencia de antecedente de abandono de tratamiento anti-TB (p= 0.000). Conclusión: Encontramos diferencias entre los pacientes con TB-DM vs No-DM, con una tendencia a peores desenlaces, con mayor estancia en UCI y mayor tasa de abondo.spa
dc.description.abstractIntroduction: Patients diagnosed with tuberculosis (TB) and diabetes mellitus (DM) may have a different clinical course than patients without DM. However, uncertainty persists about this relationship. Objective: To describe and compare the clinical radiological findings in patients diagnosed with Tuberculosis, with and without diabetes mellitus at a university hospital Methods: Cross-sectional trial of patients diagnosed with TB managed in the university hospital. Information was collected about sociodemographic, clinical, loboratory, X-ray and outcome data of the patients for five years (2012 to 2016). Univariate and then bivariate descriptive statistics were used to present the distribution of the characteristics of the patients due to the presence or absence of DM. The existence of differences between controlled and uncontrolled diabetic patients was explored (glycosylated hemoglobin <7% was defined as a controlled patient), calculating prevalence ratios of relevant variables. Results: 221 patients with TB were included, of which 32 had DM (14.48%). Median age was 66 years (Q1 48; Q3 76). Patients with TB/ DM were older in age, with a higher prevalence of hypertension and chronic kidney disease (p = 0.005). Among the patients with DM, uncontrolled patients had a higher prevalence of abandonment of anti-TB treatment (p = 0.000). Conclusion: We found differences between patients with DM-TB vs non-DM, with a tendency of worse outcomes, longer stay in ICU and higher rate of abandonment of anti-TB treatment.eng
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dc.identifier.doihttps://doi.org/10.48713/10336_14287
dc.identifier.urihttp://repository.urosario.edu.co/handle/10336/14287
dc.language.isospa
dc.publisherUniversidad del Rosariospa
dc.publisher.departmentFacultad de Medicinaspa
dc.publisher.programEspecialización en Medicina Internaspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.rights.ccAtribución-NoComercial-SinDerivadas 2.5 Colombiaspa
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dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subjectTuberculosisspa
dc.subjectDiabetes Mellitusspa
dc.subjectLatinoamericaspa
dc.subjectColombiaspa
dc.subject.ddcEnfermedades
dc.subject.keywordTuberculosiseng
dc.subject.keywordDiabetes mellituseng
dc.subject.keywordLatin Americaeng
dc.subject.keywordColombiaeng
dc.subject.lembTuberculosisspa
dc.subject.lembDiabetes Mellitusspa
dc.titleManifestaciones clínicas y radiológicas de los pacientes con tuberculosis con y sin diabetes mellitusspa
dc.typemasterThesiseng
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion
dc.type.spaTrabajo de gradospa
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