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High frequency of toxigenic Clostridium difficile and Clostridium perfringens coinfection among diarrheic patients at health care facility-onset (HCFO) and community-onset (CO) centers in Bogotá, Colombia

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dc.creatorForero, Alex J.spa
dc.creatorMuñoz, Marinaspa
dc.creatorCamargo, Milenaspa
dc.creatorSoto-De León, Sara C.spa
dc.creatorRíos-Chaparro, Dora I.spa
dc.creatorBirchenall, Claudiaspa
dc.creatorPinilla, Daríospa
dc.creatorPardo Oviedo, Juan Mauriciospa
dc.creatorJosa, Diego F.spa
dc.creatorPatarroyo, Manuel A.spa
dc.creatorRamírez, Juan Davidspa
dc.date.accessioned2020-05-26T00:09:45Z
dc.date.available2020-05-26T00:09:45Z
dc.date.created2019spa
dc.description.abstractBackground: The aim of this study was to evaluate the frequency of toxigenic C. difficile and C. perfringens infections at health care facility-onset (HCFO) and community-onset (CO), in two health care centers (HCC) in Bogotá, Colombia. A total of 220 stool samples from patients presenting diarrhea acquired at HCFO or CO were analyzed by several PCR tests. Results: We found that 65.5% (n = 144) of the population had C. difficile infection, followed by toxigenic C. difficile with 57.3% (n = 126), and finally toxigenic C. perfringens with a frequency of 32.7% (n = 72). Conclusions: This study is the first molecular detection and characterization of C. difficile and C. perfringens in HCFO and CO in Latin America and demonstrates a relevant frequency of these two species, including coinfection and strikingly diverse toxigenic profiles, especially in the CO. © 2019 The Author(s).eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1186/s13099-019-0308-7
dc.identifier.issn17574749
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/24176
dc.language.isoengspa
dc.publisherBioMed Central Ltd.spa
dc.relation.citationIssueNo. 1
dc.relation.citationTitleGut Pathogens
dc.relation.citationVolumeVol. 11
dc.relation.ispartofGut Pathogens, ISSN:17574749, Vol.11, No.1 (2019)spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85066861681&doi=10.1186%2fs13099-019-0308-7&partnerID=40&md5=0a5547b9ff430f62bebc6e4df9e01d57spa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordClostridium difficilespa
dc.subject.keywordClostridium perfringensspa
dc.subject.keywordCommunity-onsetspa
dc.subject.keywordDiarrheaspa
dc.subject.keywordHealth care facility onsetspa
dc.titleHigh frequency of toxigenic Clostridium difficile and Clostridium perfringens coinfection among diarrheic patients at health care facility-onset (HCFO) and community-onset (CO) centers in Bogotá, Colombiaspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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