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Current understanding of the mixed pain concept: a brief narrative review

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dc.creatorFreynhagen, Rainerspa
dc.creatorParada, Harold Arevalospa
dc.creatorCalderón Ospina, Carlos Alberto
dc.creatorChen, Juythelspa
dc.creatorEmril, Dessy Rakhmawatispa
dc.creatorVillacorta, Freddy Fernandezspa
dc.creatorFranco, Hectorspa
dc.creatorHo, Kok-Yuenspa
dc.creatorLara-Solares, Argeliaspa
dc.creatorLi, Carina Ching-Fanspa
dc.creatorAlvarado, Alberto Mimenzaspa
dc.creatorNimmaanrat, Sasikaanspa
dc.creatorSantos, Maria Dolmaspa
dc.creatorde Andrade, Daniel Ciampispa
dc.date.accessioned2020-05-26T00:05:41Z
dc.date.available2020-05-26T00:05:41Z
dc.date.created2019spa
dc.description.abstractDespite having been referenced in the literature for over a decade, the term “mixed pain” has never been formally defined. The strict binary classification of pain as being either purely neuropathic or nociceptive once left a good proportion of patients unclassified; even the recent adoption of “nociplastic pain” in the IASP Terminology leaves out patients who present clinically with a substantial overlap of nociceptive and neuropathic symptoms. For these patients, the term “mixed pain” is increasingly recognized and accepted by clinicians. Thus, an independent group of international multidisciplinary clinicians convened a series of informal discussions to consolidate knowledge and articulate all that is known (or, more accurately, thought to be known) and all that is not known about mixed pain. To inform the group’s discussions, a Medline search for the Medical Subject Heading “mixed pain” was performed via PubMed. The search strategy encompassed clinical trial articles and reviews from January 1990 to the present. Clinically relevant articles were selected and reviewed. This paper summarizes the group’s consensus on several key aspects of the mixed pain concept, to serve as a foundation for future attempts at generating a mechanistic and/or clinical definition of mixed pain. A definition would have important implications for the development of recommendations or guidelines for diagnosis and treatment of mixed pain. © 2019, © 2019 Informa UK Limited, trading as Taylor and Francis Group.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1080/03007995.2018.1552042
dc.identifier.issn3007995
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/23816
dc.language.isoengspa
dc.publisherTaylor and Francis Ltdspa
dc.relation.citationEndPage1018
dc.relation.citationIssueNo. 6
dc.relation.citationStartPage1011
dc.relation.citationTitleCurrent Medical Research and Opinion
dc.relation.citationVolumeVol. 35
dc.relation.ispartofCurrent Medical Research and Opinion, ISSN:3007995, Vol.35, No.6 (2019); pp. 1011-1018spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85065131581&doi=10.1080%2f03007995.2018.1552042&partnerID=40&md5=789599c73244c551f2910d7e98a78913spa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordAnalgesiaspa
dc.subject.keywordChronic painspa
dc.subject.keywordGenetic heterogeneityspa
dc.subject.keywordHumanspa
dc.subject.keywordMixed painspa
dc.subject.keywordPainspa
dc.subject.keywordPathogenesisspa
dc.subject.keywordPhenotypespa
dc.subject.keywordQuality of lifespa
dc.subject.keywordReviewspa
dc.subject.keywordScreeningspa
dc.subject.keywordSystematic reviewspa
dc.subject.keywordPainspa
dc.subject.keywordPain measurementspa
dc.subject.keywordPathophysiologyspa
dc.subject.keywordProceduresspa
dc.subject.keywordHumansspa
dc.subject.keywordPainspa
dc.subject.keywordPain measurementspa
dc.subject.keywordChronic painspa
dc.subject.keywordClassificationspa
dc.subject.keywordMixed painspa
dc.subject.keywordPain assessmentspa
dc.subject.keywordPain managementspa
dc.titleCurrent understanding of the mixed pain concept: a brief narrative reviewspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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