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Delayed lupus nephritis

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dc.creatorVarela, D-Cspa
dc.creatorQuintana, Gspa
dc.creatorSomers, E Cspa
dc.creatorRojas-Villarraga, Aspa
dc.creatorEspinosa, Gspa
dc.creatorHincapie, M-Espa
dc.creatorMcCune, W Jspa
dc.creatorCervera, Rspa
dc.creatorAnaya, Juan-Manuelspa
dc.date.accessioned2020-05-25T23:56:11Z
dc.date.available2020-05-25T23:56:11Z
dc.date.created2008spa
dc.description.abstractObjective: To describe and analyse the clinical and immunological characteristics of a large series of patients with delayed lupus nephritis (LN). Methods: A cross-sectional study was carried out. Patients with systemic lupus erythematosus (SLE) who developed renal involvement ?5 years after the first manifestation (s) of the disease (delayed LN, n = 48) were compared with patients with SLE in whom LN developed within 5 years or less after SLE appeared (early-onset LN, n = 187). A control group, the no LN (NLN) group, comprised patients with longstanding SLE (duration of disease >10 years) who had never shown signs of renal involvement (n = 164). Results: The group with delayed LN was positively associated with Sjögren's syndrome, lung involvement and antiphospholipid syndrome as compared with early LN. However, its renal clinical expression and histopathological patterns were similar to those of early-onset LN. The frequency of anti-dsDNA, anti-Sm and anti-RNP antibodies was higher in patients with LN than in the NLN group, as was the frequency of low complement levels. Jaccoud's arthropathy was a protective factor for nephritis. Conclusions: Delayed LN is not uncommon in patients with SLE. The identified risk factors might aid in its diagnosis and enhance the ability to identify patients at risk for this complication of SLE.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1136/ard.2008.088740
dc.identifier.issn00034967
dc.identifier.issn14682060
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/22356
dc.language.isoengspa
dc.relation.citationEndPage1046
dc.relation.citationIssueNo. 7
dc.relation.citationStartPage1044
dc.relation.citationTitleAnnals of the Rheumatic Diseases
dc.relation.citationVolumeVol. 67
dc.relation.ispartofAnnals of the Rheumatic Diseases, ISSN:00034967, 14682060, Vol.67, No.7 (2008); pp. 1044-1046spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-46849094953&doi=10.1136%2fard.2008.088740&partnerID=40&md5=6aa324e4862cdd95a4a0e2d4f1ce28efspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordAntiphospholipid syndromespa
dc.subject.keywordantinucleareng
dc.subject.keywordArticlespa
dc.subject.keywordAutoimmunityspa
dc.subject.keywordControlled studyspa
dc.subject.keywordDisease associationspa
dc.subject.keywordDisease coursespa
dc.subject.keywordHistopathologyspa
dc.subject.keywordHumanspa
dc.subject.keywordHuman tissuespa
dc.subject.keywordKidney biopsyspa
dc.subject.keywordLupus erythematosus nephritisspa
dc.subject.keywordMajor clinical studyspa
dc.subject.keywordNephritisspa
dc.subject.keywordNephrotic syndromespa
dc.subject.keywordPriority journalspa
dc.subject.keywordSjoegren syndromespa
dc.subject.keywordSystemic lupus erythematosusspa
dc.subject.keywordAdultspa
dc.subject.keywordAntibodieseng
dc.subject.keywordAntiphospholipid syndromespa
dc.subject.keywordCross-sectional studiesspa
dc.subject.keywordDisease susceptibilityspa
dc.subject.keywordFemalespa
dc.subject.keywordHumansspa
dc.subject.keywordLupus nephritisspa
dc.subject.keywordMalespa
dc.subject.keywordMiddle agedspa
dc.subject.keywordRisk factorsspa
dc.subject.keywordSjogren's syndromespa
dc.subject.keywordTime factorsspa
dc.titleDelayed lupus nephritisspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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