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Vitamin B12 concentration and its association with sociodemographic factors in Colombian children: Findings from the 2010 National Nutrition Survey

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Ramírez-Vélez, Robinson
Correa Bautista, Jorge Enrique
Martínez-Torres, Javier
Meneses-Echávez, José Francisco
Lobelo, Felipe




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Elsevier Inc.


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Objective: Rapid changes in dietary patterns, economic development, and urbanization in low- to middle-income countries are fueling complex malnutrition states that need better characterization using population-level data. The aim of this study was to describe the key findings related to vitamin B12 status to identify the prevalence and associated sociodemographic factors in a representative sample of children in Colombia, based on the 2010 National Nutrition Survey. Methods: We analyzed cross-sectional data from 6910 Colombian children between the ages of 5 and 12. Serum vitamin B12 concentrations were determined by chemiluminescence. Sociodemographic data was assessed by computer-assisted personal interview technology. Results: Of the children assessed, 2.8% had vitamin B12 deficiency, defined as levels and lt;200 pg/mL, and 18.1% had marginal vitamin B12 deficiency, defined as levels between 200 and 300 pg/mL. A multivariate logistic regression analysis revealed increased risks for vitamin B12 deficiency among children ages ?9 y and for those living in the eastern, western, and southern regions of the country. No significant associations were found for ethnic groups, socioeconomic status, or urbanity levels. Being 11 y of age (odds ratio [OR], 2.16; 95% confidence interval [CI], 1.56-3.00; P = 0.0001), living in the west (Pacific) region of the country (OR, 3.92; 95% CI, 3.14-4.90; P = 0.0001), and being male (OR, 1.41; 95% CI, 1.20-1.65; P = 0.0001) were the factors most strongly associated with an increased risk for vitamin B12 deficiency. Conclusions: Compared with data from other Latin American countries, Colombian children have a lower prevalence of vitamin B12 deficiency; however the prevalence of marginal deficiency is substantial. Continued surveillance and implementation of interventions to improve dietary patterns among the high-risk groups identified should be considered. © 2016 Elsevier Inc.
Palabras clave
Cyanocobalamin , Cyanocobalamin , Adolescent , Age distribution , Article , Chemoluminescence , Child , Child nutrition , Colombian , Cross-sectional study , Cyanocobalamin deficiency , Disease predisposition , Female , Gender , Geographic distribution , Human , Major clinical study , Male , Nutritional assessment , Prevalence , Priority journal , Risk assessment , Risk factor , Rural area , School child , Social status , Urban area , Vitamin blood level , Blood , Colombia , Ethnic group , Nutrition , Nutritional status , Preschool child , Socioeconomics , Statistical model , Vitamin b 12 deficiency , Child , Child , Colombia , Cross-sectional studies , Ethnic groups , Female , Humans , Logistic models , Male , Nutrition surveys , Nutritional status , Prevalence , Socioeconomic factors , Vitamin b 12 , Vitamin b 12 deficiency , Children , Deficiency , Nutrition , Prevalence , Vitamin b12