Ítem
Acceso Abierto

Cytokines and Inflammatory Mediators in Systemic Lupus Erythematosus

Mostrar el registro sencillo de la publicación
dc.creatorRojas Quintana, Manuel Eduardospa
dc.creatorRodríguez Velandia, Yhojan Alexisspa
dc.creatorJoan León, Kellyspa
dc.creatorPacheco Nieva, Yovana
dc.creatorAcosta Ampudia, Yeny Yasbleidy
dc.creatorMonsalve Carmona, Diana Marcela
dc.creatorRamírez Santana, Heily Carolinaspa
dc.creatorAnaya, Juan-Manuel
dc.date.accessioned2020-08-19T14:42:18Z
dc.date.available2020-08-19T14:42:18Z
dc.date.created2018spa
dc.description.abstractSystemic lupus erythematosus (SLE) is an autoimmune disease characterised by a breakdown in immune tolerance that induces an attack on normal tissues by the immune system. The dysfunction within both the innate and adaptive immune systems increases cytokine production, B lymphocytic overproduction of autoantibodies, and T lymphocyte activity. Cytokines and inflammatory mediators have been associated with several clinical endpoints, including the activity of disease and outcomes. In fact, some of them have been associated with different clinical subphenotypes (e.g., lupus nephritis), suggesting their role as biomarkers, and, in some cases, therapeutic targets. Thus, knowledge of the pathophysiological processes associated with the development of SLE could aid in setting up better diagnostic and therapeutic approaches to reduce the high burden of disease, and thus improve quality of life and outcomes. Herein, the authors have compiled a concise review of the clinically relevant cytokines and inflammatory mediators associated with SLE and its manifestations.eng
dc.format.mimetypeapplication/pdf
dc.identifier.issnEISSN: 2056-6395
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/27461
dc.language.isoengspa
dc.publisherEuropean medical journal. Rheumatologyspa
dc.relation.citationEndPage92
dc.relation.citationStartPage83
dc.relation.citationTitleEMJ Rheumatology
dc.relation.ispartofEuropean medical journal. Rheumatology, EISSN: 2056-6395, (July 2018); pp. 83-92spa
dc.relation.urihttps://emj.emg-health.com/wp-content/uploads/sites/2/2018/07/Cytokines-and-Inflammatory-Mediators-in-Systemic-Lupus-Erythematosus.pdfspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.sourceEMJ Rheumatologyspa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.keywordBiomarkersspa
dc.subject.keywordCytokinesspa
dc.subject.keywordInflammationspa
dc.subject.keywordInflammatory mediatorsspa
dc.subject.keywordSystemic lupus erythematosus (SLE)spa
dc.titleCytokines and Inflammatory Mediators in Systemic Lupus Erythematosusspa
dc.title.TranslatedTitleCitocinas y mediadores inflamatorios en el lupus eritematoso sistémicospa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
Archivos
Bloque original
Mostrando1 - 1 de 1
Miniatura
Nombre:
Cytokines-and-Inflammatory-Mediators-in-Systemic-Lupus-Erythematosus.pdf
Tamaño:
479.4 KB
Formato:
Adobe Portable Document Format
Descripción:
Descargar
Colecciones
Artículos