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The kaleidoscope of autoimmunity: Multiple autoimmune syndromes and familial autoimmunity

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dc.creatorAnaya, Juan-Manuelspa
dc.creatorCorena, Rodrigospa
dc.creatorCastiblanco, Johnspa
dc.creatorRojas-Villarraga, Adrianaspa
dc.creatorShoenfeld, Yehudaspa
dc.date.accessioned2020-05-26T00:07:57Z
dc.date.available2020-05-26T00:07:57Z
dc.date.created2007spa
dc.description.abstractThree related lines of evidence sustain the common origin for autoimmune diseases (ADs). First, the clinical evidence corresponding to the kaleidoscope of autoimmunity, which is the co-occurrence of various ADs within an individual or co-occurrence within members of a nuclear family. Second, the physiopathologic evidence indicating that the pathologic mechanisms might be similar among ADs. Lost, the genetic evidence indicating that autoimmune phenotypes could represent pleiotropic outcomes of nonspecific disease genes. The two conditions that better illustrate the kaleidoscope of autoimmunity are multiple autoimmune syndromes and familial autoimmunity. The multiple autoimmune syndromes consist of the presence of three or more well-defined autoimmune conditions in a single patient. The familial autoimmunity is defined as the presence of diverse ADs on multiple members of a nuclear family. Herein, both the multiple autoimmune syndromes and familial autoimmunity are discussed and various epidemiological factors considered in the context of the common genetic background of autoimmunity. © 2007 Future Drugs Ltd.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1586/1744666X.3.4.623
dc.identifier.issn1744666X
dc.identifier.issn17448409
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/24043
dc.language.isoengspa
dc.relation.citationEndPage635
dc.relation.citationIssueNo. 4
dc.relation.citationStartPage623
dc.relation.citationTitleExpert Review of Clinical Immunology
dc.relation.citationVolumeVol. 3
dc.relation.ispartofExpert Review of Clinical Immunology, ISSN:1744666X, 17448409, Vol.3, No.4 (2007); pp. 623-635spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-34547104853&doi=10.1586%2f1744666X.3.4.623&partnerID=40&md5=64259d568c3ce9d43ebc6b9d250bef91spa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordAutoimmune diseasespa
dc.subject.keywordAutoimmune polyendocrinopathyspa
dc.subject.keywordAutoimmune polyglandular syndrome type iispa
dc.subject.keywordAutoimmunityspa
dc.subject.keywordDisease predispositionspa
dc.subject.keywordDisease severityspa
dc.subject.keywordEnvironmental factorspa
dc.subject.keywordFamilial diseasespa
dc.subject.keywordFamily historyspa
dc.subject.keywordGenderspa
dc.subject.keywordHumanspa
dc.subject.keywordInheritancespa
dc.subject.keywordMedlinespa
dc.subject.keywordMosaicismspa
dc.subject.keywordNuclear familyspa
dc.subject.keywordOnset agespa
dc.subject.keywordPathophysiologyspa
dc.subject.keywordPhenotypespa
dc.subject.keywordReviewspa
dc.subject.keywordRisk factorspa
dc.subject.keywordSex differencespa
dc.subject.keywordX chromosomespa
dc.titleThe kaleidoscope of autoimmunity: Multiple autoimmune syndromes and familial autoimmunityspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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