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Sjögren’s Syndrome and Autoimmune Thyroid Disease: Two Sides of the Same Coin

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dc.creatorAnaya, Juan-Manuelspa
dc.creatorRestrepo-Jiménez P.spa
dc.creatorRodríguez Velandia, Yhojan Alexisspa
dc.creatorRodríguez Jiménez, Mónica María del Pilarspa
dc.creatorAcosta Ampudia, Yeny Yasbleidyspa
dc.creatorMonsalve Carmona, Diana Marcelaspa
dc.creatorPacheco Y.spa
dc.creatorRamírez Santana, Heily Carolinaspa
dc.creatorMolano González, Nicolásspa
dc.creatorMantilla R.D.spa
dc.date.accessioned2020-05-26T00:04:31Z
dc.date.available2020-05-26T00:04:31Z
dc.date.created2019spa
dc.description.abstractThe coexistence of Sjögren’s syndrome (SS) and autoimmune thyroid disease (AITD) has been documented. However, there is no consensus whether this coexistence should be considered as the same nosological condition or as polyautoimmunity. Thus, in this monocentric retrospective study, patients with SS alone (i.e., primary) were compared with patients with SS and AITD. In addition, a discussion of previous studies including those about genetic and environmental factors influencing the development of both conditions is presented. In our series, all patients with AITD had Hashimoto’s thyroiditis (HT). No significant differences in age, gender, age of disease onset, and disease duration were found between the two groups. Lymphadenopathy and urticaria were more frequently registered in patients with SS-HT than in patients with SS alone (p less than 0.05). Anti-Ro/SSA antibodies were more frequent in the primary SS group (p = 0.01). SS-HT patients were more likely to report a positive history of smoking (p = 0.03). The clinical expression of SS varies slightly when HT coexists. Although both entities share common physiopathological mechanisms as part of the autoimmune tautology, they are nosologically different and their coexistence should be interpreted as polyautoimmunity. Further studies based on polyautoimmunity would allow establishing a new taxonomy of autoimmune diseases. © 2018, Springer Science+Business Media, LLC, part of Springer Nature.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1007/s12016-018-8709-9
dc.identifier.issn10800549
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/23691
dc.language.isoengspa
dc.publisherHumana Press Inc.spa
dc.relation.citationEndPage374
dc.relation.citationIssueNo. 3
dc.relation.citationStartPage362
dc.relation.citationTitleClinical Reviews in Allergy and Immunology
dc.relation.citationVolumeVol. 56
dc.relation.ispartofClinical Reviews in Allergy and Immunology, ISSN:10800549, Vol.56, No.3 (2019); pp. 362-374spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85053800092&doi=10.1007%2fs12016-018-8709-9&partnerID=40&md5=dc885de28ada89602858cccb62b351bfspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordAntinuclear antibodyspa
dc.subject.keywordantinucleareng
dc.subject.keywordLa antibodyspa
dc.subject.keywordRo antibodyspa
dc.subject.keywordThyroglobulin antibodyspa
dc.subject.keywordThyroid peroxidase antibodyspa
dc.subject.keywordAntinuclear antibodyspa
dc.subject.keywordHla antigenspa
dc.subject.keywordHla antigen class 2spa
dc.subject.keywordSs-a antibodiesspa
dc.subject.keywordAdultspa
dc.subject.keywordAgespa
dc.subject.keywordArticlespa
dc.subject.keywordAutoimmune thyroiditisspa
dc.subject.keywordAutoimmunityspa
dc.subject.keywordControlled studyspa
dc.subject.keywordDisease coursespa
dc.subject.keywordDisease durationspa
dc.subject.keywordEnvironmental factorspa
dc.subject.keywordFemalespa
dc.subject.keywordGenderspa
dc.subject.keywordHashimoto diseasespa
dc.subject.keywordHeredityspa
dc.subject.keywordHumanspa
dc.subject.keywordLymphadenopathyspa
dc.subject.keywordMajor clinical studyspa
dc.subject.keywordMalespa
dc.subject.keywordOnset agespa
dc.subject.keywordPathophysiologyspa
dc.subject.keywordRetrospective studyspa
dc.subject.keywordSjoegren syndromespa
dc.subject.keywordSmokingspa
dc.subject.keywordUrticariaspa
dc.subject.keywordAdverse eventspa
dc.subject.keywordAgedspa
dc.subject.keywordB lymphocytespa
dc.subject.keywordCd4+ t lymphocytespa
dc.subject.keywordCigarette smokingspa
dc.subject.keywordColombiaspa
dc.subject.keywordComplicationspa
dc.subject.keywordGeneticsspa
dc.subject.keywordHashimoto diseasespa
dc.subject.keywordImmunologyspa
dc.subject.keywordLymphocyte activationspa
dc.subject.keywordMetabolismspa
dc.subject.keywordMiddle agedspa
dc.subject.keywordPrevalencespa
dc.subject.keywordSjoegren syndromespa
dc.subject.keywordAgedspa
dc.subject.keywordAntibodieseng
dc.subject.keywordAutoimmunityspa
dc.subject.keywordB-lymphocytesspa
dc.subject.keywordCd4-positive t-lymphocytesspa
dc.subject.keywordCigarette smokingspa
dc.subject.keywordColombiaspa
dc.subject.keywordFemalespa
dc.subject.keywordHashimoto diseasespa
dc.subject.keywordHistocompatibility antigens class iispa
dc.subject.keywordHla antigensspa
dc.subject.keywordHumansspa
dc.subject.keywordLymphocyte activationspa
dc.subject.keywordMalespa
dc.subject.keywordMiddle agedspa
dc.subject.keywordPrevalencespa
dc.subject.keywordRetrospective studiesspa
dc.subject.keywordSjogren's syndromespa
dc.subject.keywordAutoimmune diseasesspa
dc.subject.keywordAutoimmune tautologyspa
dc.subject.keywordAutoimmune thyroid diseasespa
dc.subject.keywordHashimoto’s thyroiditisspa
dc.subject.keywordPolyautoimmunityspa
dc.subject.keywordSjögren’s syndromespa
dc.subject.keywordTaxonomyspa
dc.titleSjögren’s Syndrome and Autoimmune Thyroid Disease: Two Sides of the Same Coinspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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