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Reference values of regional cerebral oxygen saturation during the first 3 days of life in preterm neonates

dc.creatorAlderliesten, Thomasspa
dc.creatorDix, Lauraspa
dc.creatorBaerts, Wimspa
dc.creatorCaicedo Dorado, Alexander
dc.creatorvan Huffel, Sabinespa
dc.creatorNaulaers, Gunnarspa
dc.creatorGroenendaal, Florisspa
dc.creatorvan Bel, Frankspa
dc.creatorLemmers, Petraspa
dc.date.accessioned2020-08-19T14:40:23Z
dc.date.available2020-08-19T14:40:23Z
dc.date.created2015-09-21spa
dc.description.abstractBackground: Currently, reliable reference values of regional cerebral oxygen saturation (rScO2) for different gestational age (GA) groups are lacking, which hampers the implementation of near-infrared spectroscopy (NIRS) alongside monitoring arterial oxygen saturation (SaO2) and blood pressure in neonatal intensive care. The aim of this study was to provide reference values for rScO2 and cerebral fractional tissue oxygen extraction (cFTOE; (SaO2 ? rScO2)/SaO2) for small adult and neonatal NIRS sensors. Methods: In this study, 999 infants born preterm (GA <32?wk) were monitored with NIRS during the first 72?h of life. Mixed modeling was used to generate reference curves grouped per 2?wk of GA. In addition, the influence of a hemodynamically significant patent ductus arteriosus, gender, and birth weight were explored. Results: Average rScO2 was ~65% at admission, increased with GA (1% per week) and followed a parabolic curve in relation to postnatal age with a peak at ~36?h. The cFTOE showed similar but inverse effects. On average, the neonatal sensor measured 10% higher than the adult sensor. Conclusion: rScO2 and cFTOE reference curves are provided for the first 72?h of life in preterm infants, which might support the broader implementation of NIRS in neonatal intensive care.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1038/pr.2015.186
dc.identifier.issnISSN: 0031-3998
dc.identifier.issnEISSN: 1530-0447
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/26855
dc.language.isoengspa
dc.publisherInternational Pediatric Research Foundationspa
dc.publisherSpringer Naturespa
dc.relation.citationEndPage64
dc.relation.citationIssueNo. 1
dc.relation.citationStartPage55
dc.relation.citationTitlePediatric Research
dc.relation.citationVolumeVol. 79
dc.relation.ispartofPediatric Research, ISSN: 0031-3998;EISSN: 1530-0447, Vol.79, No.1(January 2016); pp. 55–64spa
dc.relation.urihttps://www.nature.com/articles/pr2015186.pdfspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.sourcePediatric Researchspa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.keywordNeonatologspa
dc.subject.keywordPreterm birthspa
dc.titleReference values of regional cerebral oxygen saturation during the first 3 days of life in preterm neonatesspa
dc.title.TranslatedTitleValores de referencia de la saturación de oxígeno cerebral regional durante los primeros 3 días de vida en neonatos prematurosspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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