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Risk factors for Human Papillomavirus Exposure and Co-factors for Cervical Cancer in Latin America and the Caribbean

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dc.creatorAlmonte, Maribelspa
dc.creatorAlbero, Ginesaspa
dc.creatorMolano, Mónicaspa
dc.creatorCarcamo, Césarspa
dc.creatorGarcía, Patricia J.spa
dc.creatorPérez, Gonzalospa
dc.date.accessioned2020-05-26T00:02:07Z
dc.date.available2020-05-26T00:02:07Z
dc.date.created2008spa
dc.description.abstractThe incidence of cervical cancer in Latin America and the Caribbean (LAC) is among the highest in the world. Because there are major demographic shifts happening in LAC countries (population growth, urbanization and ageing) cervical cancer incidence and mortality will likely continue to be a significant public health problem. Overall human papillomavirus (HPV) prevalence in the LAC general population has been found to be 2-fold higher than the average worldwide prevalence. The large HPV and cancer burden may be explained by the highly prevalent HPV variants of HPV types -16 and 18, which have an increased oncogenic potential. Given the major mode of transmission of genital HPV is sexual, certain, patterns of sexual behaviour (early age at first sexual intercourse, number of sexual partners and sexual behaviour of the partner) are associated with an increased risk of HPV genital acquisition. Although HPV infection is necessary for carcinogenesis, certain co-factors (high parity, long term use of oral contraceptives, smoking and co-infection with the human immunodeficiency virus (HIV)) help in the progression from infection to cancer. Many studies that have contributed to this evidence have been carried out in LAC and are reviewed and summarised in this article. Since HPV vaccines will likely take years to implement, and many more years to show impact on disease, cervical cancer screening programmes remain as the key intervention to control disease in LAC in the years to come. © 2008 Elsevier Ltd. All rights reserved.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.vaccine.2008.06.008
dc.identifier.issn0264410X
dc.identifier.issn13588745
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/23449
dc.language.isoengspa
dc.publisherElsevier BVspa
dc.relation.citationEndPageL36
dc.relation.citationIssueNo. SUPPL. 11
dc.relation.citationStartPageL16
dc.relation.citationTitleVaccine
dc.relation.citationVolumeVol. 26
dc.relation.ispartofVaccine, ISSN:0264410X, 13588745, Vol.26, No.SUPPL. 11 (2008); pp. L16-L36spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-50849090008&doi=10.1016%2fj.vaccine.2008.06.008&partnerID=40&md5=7fb321cb7b2588097c5a17b98ed41cddspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordAntiretrovirus agentspa
dc.subject.keywordOral contraceptive agentspa
dc.subject.keywordVirus dnaspa
dc.subject.keywordWart virus vaccinespa
dc.subject.keywordAcquired immune deficiency syndromespa
dc.subject.keywordArticlespa
dc.subject.keywordCancer incidencespa
dc.subject.keywordCancer mortalityspa
dc.subject.keywordCancer preventionspa
dc.subject.keywordCancer riskspa
dc.subject.keywordCancer screeningspa
dc.subject.keywordCaribbean islandsspa
dc.subject.keywordChlamydia trachomatisspa
dc.subject.keywordCigarette smokingspa
dc.subject.keywordComorbidityspa
dc.subject.keywordDisease associationspa
dc.subject.keywordDisease coursespa
dc.subject.keywordHerpes simplex virus 2spa
dc.subject.keywordHumanspa
dc.subject.keywordHuman immunodeficiency virus infectionspa
dc.subject.keywordHuman papillomavirus type 16spa
dc.subject.keywordHuman papillomavirus type 18spa
dc.subject.keywordNonhumanspa
dc.subject.keywordOral contraceptionspa
dc.subject.keywordParityspa
dc.subject.keywordPolymerase chain reactionspa
dc.subject.keywordPriority journalspa
dc.subject.keywordRisk assessmentspa
dc.subject.keywordRisk factorspa
dc.subject.keywordSexual behaviorspa
dc.subject.keywordSexual transmissionspa
dc.subject.keywordSouth and central americaspa
dc.subject.keywordUterine cervix cancerspa
dc.subject.keywordVirus infectionspa
dc.subject.keywordVirus transmissionspa
dc.subject.keywordWart virusspa
dc.subject.keywordCaribbeanspa
dc.subject.keywordCervical cancerspa
dc.subject.keywordHpvspa
dc.subject.keywordHpv variantsspa
dc.subject.keywordLatin americaspa
dc.subject.keywordMale sexual behaviourspa
dc.subject.keywordRisk factorsspa
dc.subject.keywordSexual behaviourspa
dc.titleRisk factors for Human Papillomavirus Exposure and Co-factors for Cervical Cancer in Latin America and the Caribbeanspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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