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Identifying and characterizing a member of the RhopH1/Clag family in Plasmodium vivax

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dc.creatorMoreno-Perez D.A.spa
dc.creatorMongui A.spa
dc.creatorSoler L.N.spa
dc.creatorSanchez-Ladino M.spa
dc.creatorPatarroyo M.A.spa
dc.date.accessioned2020-05-26T00:08:58Z
dc.date.available2020-05-26T00:08:58Z
dc.date.created2011spa
dc.description.abstractPlasmodium vivax malaria caused is a public health problem that produces very high morbidity worldwide. During invasion of red blood cells the parasite requires the intervention of high molecular weight complex rhoptry proteins that are also essential for cytoadherence. PfClag9, a member of the RhopH multigene family, has been identified as being critical during Plasmodium falciparum infection. This study describes identifying and characterizing the pfclag9 ortholog in P. vivax (hereinafter named pvclag7). The pvclag7 gene is transcribed at the end of the intraerythrocytic cycle and is recognized by sera from humans who have been infected by P. vivax. PvClag7 subcellular localization has been also determined and, similar to what occurs with PfClag9, it co-localize with other proteins from the Rhoptry high molecular weight complex. © 2011 Elsevier B.V.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.gene.2011.03.007
dc.identifier.issn3781119
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/24131
dc.language.isoengspa
dc.relation.citationEndPage23
dc.relation.citationIssueNo. 1
dc.relation.citationStartPage17
dc.relation.citationTitleGene
dc.relation.citationVolumeVol. 481
dc.relation.ispartofGene, ISSN:3781119, Vol.481, No.1 (2011); pp. 17-23spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-79957655332&doi=10.1016%2fj.gene.2011.03.007&partnerID=40&md5=b718697e49b95a11722a906b8645f6f9spa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordProtein pfclag9spa
dc.subject.keywordProtein pvclag7spa
dc.subject.keywordProtozoal proteinspa
dc.subject.keywordUnclassified drugspa
dc.subject.keywordAnimal experimentspa
dc.subject.keywordAnimal modelspa
dc.subject.keywordArticlespa
dc.subject.keywordBioinformaticsspa
dc.subject.keywordCell cyclespa
dc.subject.keywordClinical articlespa
dc.subject.keywordControlled studyspa
dc.subject.keywordEnzyme linked immunosorbent assayspa
dc.subject.keywordErythrocytespa
dc.subject.keywordGene identificationspa
dc.subject.keywordGene locationspa
dc.subject.keywordHumanspa
dc.subject.keywordMolecular biologyspa
dc.subject.keywordNonhumanspa
dc.subject.keywordPlasmodium vivaxspa
dc.subject.keywordPlasmodium vivax malariaspa
dc.subject.keywordPriority journalspa
dc.subject.keywordWestern blottingspa
dc.subject.keywordChromosome mappingspa
dc.subject.keywordErythrocytesspa
dc.subject.keywordHumansspa
dc.subject.keywordMultigene familyspa
dc.subject.keywordPlasmodium vivaxspa
dc.subject.keywordProtozoan proteinsspa
dc.subject.keywordPlasmodium falciparumspa
dc.subject.keywordPlasmodium vivaxspa
dc.subject.keywordCytoadherencespa
dc.subject.keywordMalariaspa
dc.subject.keywordMultigene familyspa
dc.subject.keywordPlasmodium falciparumspa
dc.subject.keywordPlasmodium vivaxspa
dc.subject.keywordRhoptryspa
dc.titleIdentifying and characterizing a member of the RhopH1/Clag family in Plasmodium vivaxspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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