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Effectiveness of HIIT compared to moderate continuous training in improving vascular parameters in inactive adults

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dc.creatorRamírez-Vélez, Robinson
dc.creatorHernández-Quiñones, Paula Andreaspa
dc.creatorTordecilla-Sanders, Alejandraspa
dc.creatorÁlvarez, Cristianspa
dc.creatorRamírez-Campillo, Rodrigospa
dc.creatorIzquierdo, Mikelspa
dc.creatorCorrea Bautista, Jorge Enrique
dc.creatorGarcia-Hermoso, Antoniospa
dc.creatorGarcia, Ronald G.spa
dc.date.accessioned2020-05-25T23:56:50Z
dc.date.available2020-05-25T23:56:50Z
dc.date.created2019spa
dc.description.abstractBackground: Strong evidence shows that physical inactivity increases the risk of many adverse health conditions, including major non-communicable diseases, such as cardiovascular disease (CVD), metabolic syndrome, and breast and colon cancers, and shortens life expectancy. We aimed to determine the effects of moderate (MCT)- versus high-intensity interval training (HIT) on vascular function parameters in physically inactive adults. We hypothesized that individualized HIT prescription would improve the vascular function parameters more than the MCT in a greater proportion of individuals. Methods: Twenty-one inactive adults were randomly allocated to receive either MCT group (60-75% of their heart rate reserve, [HRR] or HIT group (4 min at 85-95% of peak HRR), 3 days a week for 12 weeks. Vascular function (brachial artery flow-mediated dilation, FMD [%], normalized brachial artery flow-mediated dilation, FMDn [%], aortic pulse wave velocity, PWV [m·s - 1 ], AIx, augmentation index: aortic and brachial [%]), were measured at baseline and over 12 weeks of training. In order for a participant to be considered a responder to improvements in vascular function parameters (FMDn and PWV), the typical error was calculated in a favorable direction. Results: FMD changed by - 1.0% (SE 2.1, d = 0.388) in the MCT group, and + 1.8% (SE 1.8, d = 0.699) in the HIT group (no significant difference between groups: 2.9% [95% CI, - 3.0 to 8.8]. PWV changed by + 0.1 m·s - 1 (SE 0.2, d = 0.087) in the MCT group but decreased by - 0.4 m·s - 1 in the HIT group (SE 0.2, d = 0.497), with significant difference between groups: - 0.4 [95% CI, - 0.2 to - 0.7]. There was not a significant difference in the prevalence of no-responder for FMD (%) between the MCT and HIT groups (66% versus 36%, P = 0.157). Regarding PWV (m·s - 1 ), an analysis showed that the prevalence of no-responder was 77% (7 cases) in the MCT group and 45% (5 cases) in the HIT group (P = 0.114). Conclusions: Under the conditions of the present study, both groups experienced changed in vascular function parameters. Compared to MCT group, HIT is more efficacious for improving FMD and decreasing PWV, in physically inactive adults. Trial registration: ClinicalTrials.gov NCT02738385 registered on 23 March 2016. © 2019 The Author(s).eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1186/s12944-019-0981-z
dc.identifier.issn1476511X
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/22539
dc.language.isoengspa
dc.publisherBioMed Central Ltd.spa
dc.relation.citationIssueNo. 1
dc.relation.citationTitleLipids in Health and Disease
dc.relation.citationVolumeVol. 18
dc.relation.ispartofLipids in Health and Disease, ISSN:1476511X, Vol.18, No.1 (2019)spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85061125443&doi=10.1186%2fs12944-019-0981-z&partnerID=40&md5=87eb3cf309764f9b696d6610a776143fspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordAdultspa
dc.subject.keywordvasculareng
dc.subject.keywordAerobic exercisespa
dc.subject.keywordAnalytical errorspa
dc.subject.keywordArterial stiffnessspa
dc.subject.keywordArtery blood flowspa
dc.subject.keywordArticlespa
dc.subject.keywordAugmentation indexspa
dc.subject.keywordBlood vessel functionspa
dc.subject.keywordBrachial arteryspa
dc.subject.keywordCardiovascular diseasespa
dc.subject.keywordCardiovascular parametersspa
dc.subject.keywordClinical effectivenessspa
dc.subject.keywordControlled studyspa
dc.subject.keywordEndothelial dysfunctionspa
dc.subject.keywordExercise intensityspa
dc.subject.keywordHeart ratespa
dc.subject.keywordHigh intensity interval trainingspa
dc.subject.keywordHumanspa
dc.subject.keywordModerate continuous trainingspa
dc.subject.keywordPersonalized medicinespa
dc.subject.keywordPhysical inactivityspa
dc.subject.keywordPrescriptionspa
dc.subject.keywordPrevalencespa
dc.subject.keywordPulse wavespa
dc.subject.keywordRandomized controlled trialspa
dc.subject.keywordSedentary lifestylespa
dc.subject.keywordTherapy effectspa
dc.subject.keywordVascular endotheliumspa
dc.subject.keywordVasodilatationspa
dc.subject.keywordAdolescentspa
dc.subject.keywordBlood vesselspa
dc.subject.keywordCardiovascular diseasespa
dc.subject.keywordExercisespa
dc.subject.keywordExercise testspa
dc.subject.keywordFemalespa
dc.subject.keywordMalespa
dc.subject.keywordMiddle agedspa
dc.subject.keywordPhysiologyspa
dc.subject.keywordYoung adultspa
dc.subject.keywordAdolescentspa
dc.subject.keywordAdultspa
dc.subject.keywordBlood vesselsspa
dc.subject.keywordCardiovascular diseasesspa
dc.subject.keywordEndotheliumeng
dc.subject.keywordExercisespa
dc.subject.keywordExercise testspa
dc.subject.keywordFemalespa
dc.subject.keywordHeart ratespa
dc.subject.keywordHigh-intensity interval trainingspa
dc.subject.keywordHumansspa
dc.subject.keywordMalespa
dc.subject.keywordMiddle agedspa
dc.subject.keywordSedentary behaviorspa
dc.subject.keywordYoung adultspa
dc.subject.keywordAerobic exercisespa
dc.subject.keywordArterial stiffnessspa
dc.subject.keywordCardiovascular disease preventionspa
dc.subject.keywordEndothelial dysfunctionspa
dc.subject.keywordSedentarismspa
dc.titleEffectiveness of HIIT compared to moderate continuous training in improving vascular parameters in inactive adultsspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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