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The impact of comorbidities on costs, utilities and health-related quality of life among HIV patients in a clinical setting in Bogotá

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Van Duin, Mark JM
Conde, Rafael
Wijnen, Ben
Evers, Silvia MAA
González Rodríguez, Javier Leonardo
Govers, Mark JG
Hiligsmann, Mickaël



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Taylor and Francis Ltd

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Background: This study aimed to assess the impact of comorbidities (CMs) on costs, utilities and health-related quality of life (HRQOL) among HIV patients in Colombia. Methods: A cross-sectional study was conducted among 138 HIV patients at an outpatient clinic in Bogotá to assess their costs, utilities (EQ5D-5L) and HRQOL (EQ-VAS). CMs and other covariates were gathered from patient records. Multiple regression models were conducted to assess the impact of CMs. Results: Of all patients, 72% experienced CMs; of these, half experienced ?2 CMs (N = 49). CMs had a statistically significant impact on utilities when the EQ5D-5L (P = 0.022) was applied among patient with ?2 CMs. No statistical significance was found for the impact of CMs on costs. Conclusion: This study suggests that having multiple CMs significantly influences utility, and CMs have some impact on HRQOL measured using the EQ-VAS but this effect is at the border of significance. No significant impact was observed on costs. © 2016 The Author(s). Published by Informa UK Limited, trading as Taylor and Francis Group.
Palabras clave
Colombia , Comorbidity , Cross-sectional study , Family , Human , Human immunodeficiency virus , Major clinical study , Medical record , Model , Multiple regression , Nonhuman , Outpatient department , Quality of life , Statistical significance , Adult , Ambulatory care , Colombia , Comorbidity , Economics , Female , Health care cost , HIV Infections , Male , Middle aged , Pathophysiology , Regression analysis , Adult , Ambulatory Care , Colombia , Comorbidity , Cross-Sectional Studies , Female , Health Care Costs , HIV Infections , Humans , Male , Middle Aged , Quality of Life , Regression Analysis , Acquired Immune Deficiency Syndrome (AIDS) , Bogotá , Burden of disease , Colombia , Health-related quality of life (HRQOL) , Healthcare costs , Human Immunodeficiency Virus (HIV) , Patient and family costs , Utility
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