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Identifying the factors for improving quality of oral fluorescein angiography

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dc.creatorAmador-Patarroyo, Manuel Jspa
dc.creatorLin, Tiezhuspa
dc.creatorMeshi, Amitspa
dc.creatorDans, Kunny Cspa
dc.creatorChen, Kevinspa
dc.creatorBorooah, Shyamangaspa
dc.creatorMolano-González, Nicolas
dc.creatorDíaz-Rojas, Jorge Aspa
dc.creatorFreeman, William Rspa
dc.date.accessioned2020-05-26T00:03:39Z
dc.date.available2020-05-26T00:03:39Z
dc.date.created2020spa
dc.description.abstractAim To evaluate the quality of oral fluorescein angiography (FA) in relation to food intake. Methods This is an observational, case-crossover study. We collected information from patients undergoing routine oral FA for retinal disease at the Shiley Eye Institute. Eighty patients (160 eyes) were analysed. Fasting and non-fasting images of the same patient were recorded, compared and analysed for different image quality parameters and clinical relevance by experienced retina specialists. Results When analysing the images, intergrader agreement was moderate to good with a Kappa averaging 0.60 (0.5-0.85). When patients were fasting pre-imaging, better angiography quality scores were achieved when compared with images taken when patients were non-fasting (mean 0.84 vs 0.72, p less than 0.001). Multivariate analysis showed that non-fasting patients with higher body mass index had the worst scores. Other clinical parameters, such as staining of drusen, staining of disciform scars or central and peripapillary atrophy, were also significantly better during the pre-fasting exam (p less than 0.001). Oral FA was approximately 22% faster (time to fluorescein dye appearance) under fasting conditions than non-fasting (mean±SD, minutes, 18.7±6.9 vs 25.14±8.1, p less than 0.001). Conclusion Fasting oral FA provided significantly better quality images as well as faster optimal imaging times when compared with non-fasting oral FA. By improving its overall quality, oral FA could be a useful adjunctive examination to optical coherence tomography (OCT) and OCT angiography in patients who require FA studies but who have difficult access or refuse an invasive procedure. © Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1136/bjophthalmol-2019-314187
dc.identifier.issn71161
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/23614
dc.language.isoengspa
dc.publisherBMJ Publishing Groupspa
dc.relation.citationEndPage508
dc.relation.citationIssueNo. 4
dc.relation.citationStartPage504
dc.relation.citationTitleBritish Journal of Ophthalmology
dc.relation.citationVolumeVol. 104
dc.relation.ispartofBritish Journal of Ophthalmology, ISSN:71161, Vol.104, No.4 (2020); pp. 504-508spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85068591211&doi=10.1136%2fbjophthalmol-2019-314187&partnerID=40&md5=0a765611d8413518fc2dcb43cd65f853spa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordDyespa
dc.subject.keywordAgedspa
dc.subject.keywordArticlespa
dc.subject.keywordBody massspa
dc.subject.keywordCross-sectional studyspa
dc.subject.keywordFastingspa
dc.subject.keywordFemalespa
dc.subject.keywordFluorescence angiographyspa
dc.subject.keywordFood intakespa
dc.subject.keywordHumanspa
dc.subject.keywordImage analysisspa
dc.subject.keywordImage qualityspa
dc.subject.keywordMacular degenerationspa
dc.subject.keywordMajor clinical studyspa
dc.subject.keywordMalespa
dc.subject.keywordMedical specialistspa
dc.subject.keywordObservational studyspa
dc.subject.keywordPatient safetyspa
dc.subject.keywordPersonal experiencespa
dc.subject.keywordPriority journalspa
dc.subject.keywordRetina diseasespa
dc.subject.keywordScoring systemspa
dc.subject.keywordStainingspa
dc.subject.keywordDiagnostic tests/investigationspa
dc.subject.keywordImagingspa
dc.subject.keywordMaculaspa
dc.subject.keywordPharmacologyspa
dc.subject.keywordPhysiologyspa
dc.titleIdentifying the factors for improving quality of oral fluorescein angiographyspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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