Ítem
Acceso Abierto

The role of clinical, biological, and socioeconomic factors on the development of resilience in women with autorimmune rheumatic diseases : a cross-sectional study

dc.contributorAnaya, Juan Manuel
dc.contributorMonsalve, Diana M.
dc.contributorPacheco, Yovana
dc.contributorRamirez-Santana, Carolina
dc.contributorRodríguez-Jimenez, Monica
dc.contributorRodríguez, Yhojan
dc.contributorMantilla, Ruben Dario
dc.contributor.advisorAcosta Ampudia, Yeny Yasbleidy
dc.contributor.advisorMolano González, Nicolás
dc.creatorRojas Quintana, Manuel Eduardo
dc.creator.degreeMagíster en epidemiologíaspa
dc.creator.degreetypeFull timespa
dc.date.accessioned2019-06-12T13:35:10Z
dc.date.available2019-06-12T13:35:10Z
dc.date.created2019-05-30
dc.date.issued2019
dc.description.abstractBACKGROUND: Resilience is considered the capability to positively respond to adverse events. Since this capacity in considered a “continuum” process, long-term stressors and psychosocial factors are thought to be crucial for resilience development, especially in those patients with chronic inflammatory systemic diseases. However, the role of clinical, biological and socioeconomic characteristics in autoimmune rheumatic diseases (ARDs) is still unknown. OBJECTIVE To evaluate the association between resilience and socioeconomic, biological and clinical factors in four autoimmune rheumatic diseases (ARDs) namely: systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), Sjögren’s syndrome (SS) and systemic sclerosis (SSc). METHODS: A cross-sectional study in 188 women with SLE (n= 70), RA (n= 51), SS (n= 32), and SSc (n= 35) was done. Resilience was evaluated by the “Brief Resilience Scale”, whereas independent factors including age, age at onset, duration of disease, socioeconomic status, excersice, severity of symptoms and polyautoimmunity (PolyA) were evaluated by surveys and chart reviews. A panel of 15 serum cytokines and 14 autoantibodies were evaluated simultaneously. Bivariate, classification and regression trees (CART), and multiple linear regressions were used to analyze data. RESULTS: CART analysis showed that patients younger than 48 years with SLE, RA, and SSc who had low socioeconomic status showed the lowest resilience scores, whereas those patients between 48 and 66 years exhibited the highest resilience levels despite socioeconomic status. Interestingly, regular physical activity was associated with highest resilience in SSc. In addition, Interleukin-6 (IL-6) was associated low resilience scores (β= -0.581120, p=0.02) and with severity of symptoms (β=1.8395, p=0.04) in SSc. Neither PolyA nor severity of symptoms influenced resilience in the four ARDs studied. Cytokine levels did not significantly differ between groups based on regular physical activity. CONCLUSIONS: Resilience is a continuum trait associated to socioeconomic status and age. In addition, IL-6 and exercise are key factors for resilience in SSc. These results highlight the relevance of biological and socioeconomic factors in the development of resilience in autoimmunity.eng
dc.description.sponsorshipCentro de Estudio de Enfermedades Autoinmunes (CREA)spa
dc.description.sponsorshipUniversidad del Rosario (ABN011)spa
dc.description.sponsorshipColciencias (Grant No 122254531722/Grant No0425-2013)spa
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.48713/10336_19850
dc.identifier.urihttp://repository.urosario.edu.co/handle/10336/19850
dc.language.isospa
dc.publisherUniversidad del Rosariospa
dc.publisher.departmentMaestría en Actividad Física y Saludspa
dc.publisher.otherUniversidad CESspa
dc.publisher.programMaestría en Epidemiologíaspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.rights.licenciaEL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma. PARGRAFO: En caso de presentarse cualquier reclamación o acción por parte de un tercero en cuanto a los derechos de autor sobre la obra en cuestión, EL AUTOR, asumirá toda la responsabilidad, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos la universidad actúa como un tercero de buena fe. EL AUTOR, autoriza a LA UNIVERSIDAD DEL ROSARIO, para que en los términos establecidos en la Ley 23 de 1982, Ley 44 de 1993, Decisión andina 351 de 1993, Decreto 460 de 1995 y demás normas generales sobre la materia, utilice y use la obra objeto de la presente autorización. -------------------------------------- POLITICA DE TRATAMIENTO DE DATOS PERSONALES. Declaro que autorizo previa y de forma informada el tratamiento de mis datos personales por parte de LA UNIVERSIDAD DEL ROSARIO para fines académicos y en aplicación de convenios con terceros o servicios conexos con actividades propias de la academia, con estricto cumplimiento de los principios de ley. Para el correcto ejercicio de mi derecho de habeas data cuento con la cuenta de correo habeasdata@urosario.edu.co, donde previa identificación podré solicitar la consulta, corrección y supresión de mis datos.spa
dc.source.bibliographicCitation1. MINSALUD M de S y PS. Encuesta Nacional de Salud Mental 2015. Tomo I. 2015. 384 p.spa
dc.source.bibliographicCitation2. von dem Knesebeck O, Mnich E, Daubmann A, Wegscheider K, Angermeyer MC, Lambert M, et al. Socioeconomic status and beliefs about depression, schizophrenia and eating disorders. Social Psychiatry and Psychiatric Epidemiology. 2013 May;48(5):775–82.spa
dc.source.bibliographicCitation3. Rojas-Villarraga A, Amaya-Amaya J, Rodriguez-Rodriguez A, Mantilla RD, Anaya J-M. Introducing polyautoimmunity: secondary autoimmune diseases no longer exist. Autoimmune diseases [Internet]. 2012;2012(1):254319. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22454759spa
dc.source.bibliographicCitation4. Lerner A, Jeremias P, Matthias T. The World Incidence and Prevalence of Autoimmune Diseases is Increasing. International Journal of Celiac Disease. 2015 Nov;3(4):151–5.spa
dc.source.bibliographicCitation5. Westhoff G, Dörner T, Zink A. Fatigue and depression predict physician visits and work disability in women with primary Sjögren’s syndrome: results from a cohort study. Rheumatology [Internet]. 2012 Feb;51(2):262–9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21705778spa
dc.source.bibliographicCitation6. Rogers HL, Brotherton HT, Olivera Plaza SL, Segura Durán MA, Peña Altamar ML. Depressive and anxiety symptoms and social support are independently associated with disease-specific quality of life in Colombian patients with rheumatoid arthritis. Revista brasileira de reumatologia [Internet]. 2015;55(5):406–13. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25816759spa
dc.source.bibliographicCitation7. Thombs BD, Taillefer SS, Hudson M, Baron M. Depression in patients with systemic sclerosis: a systematic review of the evidence. Arthritis and rheumatism [Internet]. 2007 Aug 15;57(6):1089–97. Available from: http://www.ncbi.nlm.nih.gov/pubmed/17665491spa
dc.source.bibliographicCitation8. Baubet T, Ranque B, Taïeb O, Bérezné A, Bricou O, Mehallel S, et al. Mood and anxiety disorders in systemic sclerosis patients. Presse medicale [Internet]. 2011 Feb;40(2):e111-9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21055901spa
dc.source.bibliographicCitation9. Kheirandish M, Faezi ST, Paragomi P, Akhlaghi M, Gharibdoost F, Shahali A, et al. Prevalence and severity of depression and anxiety in patients with systemic lupus erythematosus: An epidemiologic study in Iranian patients. Modern rheumatology [Internet]. 2015 May;25(3):405–9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25295916spa
dc.source.bibliographicCitation10. Zuñiga Zambrano YC, Vásquez R. [Psychiatric Disorders in Pediatric Patients With Systemic Lupus Erythematosus in a Reference Hospital]. Revista Colombiana De Psiquiatria. 2014 Jun;43(2):73–9.spa
dc.source.bibliographicCitation11. Smith BW, Dalen J, Wiggins K, Tooley E, Christopher P, Bernard J. The brief resilience scale: assessing the ability to bounce back. International journal of behavioral medicine [Internet]. 2008;15(3):194–200. Available from: http://www.ncbi.nlm.nih.gov/pubmed/18696313spa
dc.source.bibliographicCitation12. Najjar S, Pearlman DM, Alper K, Najjar A, Devinsky O. Neuroinflammation and psychiatric illness. Journal of neuroinflammation [Internet]. 2013 Apr 1;10(1):43. Available from: http://jneuroinflammation.biomedcentral.com/articles/10.1186/1742-2094-10-43spa
dc.source.bibliographicCitation13. Cal SF, Santiago MB. Resilience in systemic lupus erythematosus. Psychology, health & medicine [Internet]. 2013;18(5):558–63. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23350645spa
dc.source.bibliographicCitation14. Liu L, Xu X, Xu N, Wang L. Disease activity, resilience and health-related quality of life in Chinese patients with rheumatoid arthritis: a multi-center, cross-sectional study. Health and quality of life outcomes [Internet]. 2017 Jul 24;15(1):149. Available from: http://www.ncbi.nlm.nih.gov/pubmed/28738816spa
dc.source.bibliographicCitation15. Margarita J, Vinaccia S. Resiliencia: una perspectiva desde la enfermedad crónica en población adulta. Pensamiento Psicológico. 2011;9(17):69–82.spa
dc.source.bibliographicCitation16. Stewart DE, Yuen T. A systematic review of resilience in the physically ill. Psychosomatics [Internet]. 2011;52(3):199–209. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21565591spa
dc.source.bibliographicCitation17. Tosevski DLDL, Milovancevic MPMP. Stressful life events and physical health. Current Opinion in Psychiatry [Internet]. 2006 Mar;19(2):184–9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16612201spa
dc.source.bibliographicCitation18. Quiceno JM, Vinaccia S. Resiliencia, percepción de la enfermedad, creencia y afrontamiento espiritual religioso y calidad de vida relacionada con la salud en pacientes con diagnóstico de artritis reumatoide. Psicol desde el caribe. 2013;30(3):590–619.spa
dc.source.bibliographicCitation19. Smith BW, Zautra AJ. Vulnerability and resilience in women with arthritis: test of a two-factor model. Journal of consulting and clinical psychology [Internet]. 2008 Oct;76(5):799–810. Available from: http://www.ncbi.nlm.nih.gov/pubmed/18837597spa
dc.source.bibliographicCitation20. McEwen BS. Stress, adaptation, and disease. Allostasis and allostatic load. Annals of the New York Academy of Sciences [Internet]. 1998 May 1;840(1):33–44. Available from: http://www.ncbi.nlm.nih.gov/pubmed/9629234spa
dc.source.bibliographicCitation21. Somers TJ, Kurakula PC, Criscione-Schreiber L, Keefe FJ, Clowse MEB. Self-efficacy and pain catastrophizing in systemic lupus erythematosus: relationship to pain, stiffness, fatigue, and psychological distress. Arthritis care & research [Internet]. 2012 Sep;64(9):1334–40. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22505314spa
dc.source.bibliographicCitation22. Graninger M. [Behavioral training as additional therapy approach for rheumatoid arthritis]. Zeitschrift fur Rheumatologie [Internet]. 2015 Sep;74(7):579–83. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26334968spa
dc.source.bibliographicCitation23. Pfau ML, Russo SJ. Peripheral and central mechanisms of stress resilience. Neurobiology of Stress [Internet]. 2015 Jan;1(1):66–79. Available from: https://linkinghub.elsevier.com/retrieve/pii/S2352289514000058spa
dc.source.bibliographicCitation24. Perricone C, Shoenfeld N, Agmon-Levin N, de Carolis C, Perricone R, Shoenfeld Y. Smell and autoimmunity: a comprehensive review. Clinical reviews in allergy & immunology [Internet]. 2013 Aug;45(1):87–96. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23233263spa
dc.source.bibliographicCitation25. Quintero OL, Amador-Patarroyo MJ, Montoya-Ortiz G, Rojas-Villarraga A, Anaya J-M. Autoimmune disease and gender: plausible mechanisms for the female predominance of autoimmunity. Journal of autoimmunity [Internet]. 2012 May;38(2–3):J109-19. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22079680spa
dc.source.bibliographicCitation26. Anaya J-M. The diagnosis and clinical significance of polyautoimmunity. Autoimmunity reviews [Internet]. 2014;13(4–5):423–6. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24424171spa
dc.source.bibliographicCitation27. Anaya J-M, Duarte-Rey C, Sarmiento-Monroy JC, Bardey D, Castiblanco J, Rojas-Villarraga A. Personalized medicine. Closing the gap between knowledge and clinical practice. Autoimmunity reviews [Internet]. 2016 Aug;15(8):833–42. Available from: http://www.ncbi.nlm.nih.gov/pubmed/27302209spa
dc.source.bibliographicCitation28. Anaya J-M, Restrepo-Jimenez P, Ramirez-Santana C. The autoimmune ecology: an update. Current opinion in rheumatology. 2018 Feb; In press. Available from: https://www.ncbi.nlm.nih.gov/pubmed/29438164spa
dc.source.bibliographicCitation29. Anaya J-M, Ramirez-Santana C, Alzate MA, Molano-Gonzalez N, Rojas-Villarraga A. The Autoimmune Ecology. Frontiers in immunology [Internet]. 2016;7:139. Available from: http://www.ncbi.nlm.nih.gov/pubmed/27199979spa
dc.source.bibliographicCitation30. Shoenfeld Y, Isenberg DA. The mosaic of autoimmunity. Immunology today [Internet]. 1989 Apr;10(4):123–6. Available from: http://www.ncbi.nlm.nih.gov/pubmed/2665774spa
dc.source.bibliographicCitation31. Anaya J-M. The autoimmune tautology. Arthritis research & therapy [Internet]. 2010;12(6):147. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21092150spa
dc.source.bibliographicCitation32. Pacheco Y, Barahona-Correa J, Monsalve DM, Acosta-Ampudia Y, Rojas M, Rodríguez Y, et al. Cytokine and autoantibody clusters interaction in systemic lupus erythematosus. Journal of translational medicine [Internet]. 2017 Nov 25;15(1):239. Available from: http://www.ncbi.nlm.nih.gov/pubmed/29178890spa
dc.source.bibliographicCitation33. Kared H, Camous X, Larbi A. T cells and their cytokines in persistent stimulation of the immune system. Current opinion in immunology [Internet]. 2014 Aug;29:79–85. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24880502spa
dc.source.bibliographicCitation34. Rovin BH, Lu L, Zhang X. A novel interleukin-8 polymorphism is associated with severe systemic lupus erythematosus nephritis. Kidney international [Internet]. 2002 Jul;62(1):261–5. Available from: http://www.ncbi.nlm.nih.gov/pubmed/12081586spa
dc.source.bibliographicCitation35. Yung S, Ng CYC, Au KY, Cheung KF, Zhang Q, Zhang C, et al. Binding of anti-dsDNA antibodies to proximal tubular epithelial cells contributes to renal tubulointerstitial inflammation. Clinical science [Internet]. 2017 Jan 1;131(1):49–67. Available from: http://www.ncbi.nlm.nih.gov/pubmed/27780843spa
dc.source.bibliographicCitation36. Yoshio T, Okamoto H, Kurasawa K, Dei Y, Hirohata S, Minota S. IL-6, IL-8, IP-10, MCP-1 and G-CSF are significantly increased in cerebrospinal fluid but not in sera of patients with central neuropsychiatric lupus erythematosus. Lupus [Internet]. 2016 Aug;25(9):997–1003. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26846690spa
dc.source.bibliographicCitation37. Eilertsen GØ, Nikolaisen C, Becker-Merok A, Nossent JC. Interleukin-6 promotes arthritis and joint deformation in patients with systemic lupus erythematosus. Lupus [Internet]. 2011 May;20(6):607–13. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21422077spa
dc.source.bibliographicCitation38. Voronov E, Dayan M, Zinger H, Gayvoronsky L, Lin J-P, Iwakura Y, et al. IL-1 beta-deficient mice are resistant to induction of experimental SLE. European cytokine network [Internet]. 2006 Jun;17(2):109–16. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16840029spa
dc.source.bibliographicCitation39. Boswell JM, Yui MA, Endres S, Burt DW, Kelley VE. Novel and enhanced IL-1 gene expression in autoimmune mice with lupus. Journal of immunology [Internet]. 1988 Jul 1;141(1):118–24. Available from: http://www.ncbi.nlm.nih.gov/pubmed/3259964spa
dc.source.bibliographicCitation40. Qiu F, Song L, Yang N, Li X. Glucocorticoid downregulates expression of IL-12 family cytokines in systemic lupus erythematosus patients. Lupus [Internet]. 2013 Sep;22(10):1011–6. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23884985spa
dc.source.bibliographicCitation41. Fuschiotti P, Larregina AT, Ho J, Feghali-Bostwick C, Medsger TA. Interleukin-13-producing CD8+ T cells mediate dermal fibrosis in patients with systemic sclerosis. Arthritis and rheumatism [Internet]. 2013 Jan;65(1):236–46. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23001877spa
dc.source.bibliographicCitation42. Barnes TC, Anderson ME, Moots RJ. The many faces of interleukin-6: the role of IL-6 in inflammation, vasculopathy, and fibrosis in systemic sclerosis. International journal of rheumatology [Internet]. 2011;2011:721608. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21941555spa
dc.source.bibliographicCitation43. Rolla G, Fusaro E, Nicola S, Bucca C, Peroni C, Parisi S, et al. Th-17 cytokines and interstitial lung involvement in systemic sclerosis. Journal of breath research [Internet]. 2016 Nov 21;10(4):046013. Available from: http://www.ncbi.nlm.nih.gov/pubmed/27869103spa
dc.source.bibliographicCitation44. Meloni F, Solari N, Cavagna L, Morosini M, Montecucco CM, Fietta AM. Frequency of Th1, Th2 and Th17 producing T lymphocytes in bronchoalveolar lavage of patients with systemic sclerosis. Clinical and experimental rheumatology. 2009;27(5):765–72.spa
dc.source.bibliographicCitation45. Dumoitier N, Chaigne B, Regent A, Lofek S, Mhibik M, Dorfmuller P, et al. Scleroderma Peripheral B Lymphocytes Secrete Interleukin-6 and Transforming Growth Factor beta and Activate Fibroblasts. Arthritis & rheumatology. 2017 May;69(5):1078–89.spa
dc.source.bibliographicCitation46. Zhang L-W, Zhou P-R, Wei P, Cong X, Wu L-L, Hua H. Expression of interleukin-17 in primary Sjögren’s syndrome and the correlation with disease severity: A systematic review and meta-analysis. Scandinavian journal of immunology [Internet]. 2018 Apr;87(4):e12649. Available from: http://www.ncbi.nlm.nih.gov/pubmed/29476557spa
dc.source.bibliographicCitation47. Kirschner M. Systems Medicine: Sketching the Landscape. Methods in molecular biology. 2016;1386:3–15.spa
dc.source.bibliographicCitation48. Calixto O-J, Anaya J-M. Socioeconomic status. The relationship with health and autoimmune diseases. Autoimmunity reviews [Internet]. 2014 Jun;13(6):641–54. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24418307spa
dc.source.bibliographicCitation49. Jacobi CE, Mol GD, Boshuizen HC, Rupp I, Dinant HJ, Van Den Bos GAM. Impact of socioeconomic status on the course of rheumatoid arthritis and on related use of health care services. Arthritis and rheumatism [Internet]. 2003 Aug 15;49(4):567–73. Available from: http://www.ncbi.nlm.nih.gov/pubmed/12910565spa
dc.source.bibliographicCitation50. Margaretten M, Julian L, Katz P, Yelin E. Depression in patients with rheumatoid arthritis: description, causes and mechanisms. International journal of clinical rheumatology [Internet]. 2011;6(6):617–23. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22211138spa
dc.source.bibliographicCitation51. Cadena J, Vinaccia S, Pérez A, Rico MI, Hinojosa R, Anaya J-M. The impact of disease activity on the quality of life, mental health status, and family dysfunction in colombian patients with rheumatoid arthritis. Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases [Internet]. 2003 Jun;9(3):142–50. Available from: http://www.ncbi.nlm.nih.gov/pubmed/17041449spa
dc.source.bibliographicCitation52. Walsh SJ, Gilchrist A. Geographical clustering of mortality from systemic lupus erythematosus in the United States: contributions of poverty, Hispanic ethnicity and solar radiation. Lupus [Internet]. 2006;15(10):662–70. Available from: http://www.ncbi.nlm.nih.gov/pubmed/17120593spa
dc.source.bibliographicCitation53. Alarcón GS, Bastian HM, Beasley TM, Roseman JM, Tan FK, Fessler BJ, et al. Systemic lupus erythematosus in a multi-ethnic cohort (LUMINA) XXXII: [corrected] contributions of admixture and socioeconomic status to renal involvement. Lupus [Internet]. 2006;15(1):26–31. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16482742spa
dc.source.bibliographicCitation54. Smolen JS, Aletaha D, McInnes IB. Rheumatoid arthritis. The Lancet [Internet]. 2016 Oct;388(10055):2023–38. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0140673616301738spa
dc.source.bibliographicCitation55. Singh JA, Saag KG, Bridges SL, Akl EA, Bannuru RR, Sullivan MC, et al. 2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis. Arthritis & rheumatology [Internet]. 2016 Jan;68(1):1–26. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26545940spa
dc.source.bibliographicCitation56. Sweeney S e., Harris ED, Firestein G s. Clinical Features of Rheumatoid Arthritis. In: Kelly’s Textbook of Rheumatology. 9th ed. Philadelphia; 2013. p. 1109-1136e4.spa
dc.source.bibliographicCitation57. Davis JM, Matteson EL. My Treatment Approach to Rheumatoid Arthritis. Mayo Clinic Proceedings [Internet]. 2012 Jul;87(7):659–73. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0025619612004727spa
dc.source.bibliographicCitation58. Kasturi S, Goldstein BL, Malspeis S, Karlson EW, Costenbader KH. Comparison of the 1987 American College of Rheumatology and the 2010 American College of Rheumatology/European League against Rheumatism Criteria for Classification of Rheumatoid Arthritis in the Nurses’ Health Study Cohorts. Rheumatology international. 2014 Mar;34(3):407–11.spa
dc.source.bibliographicCitation59. Sheehy C, Evans V, Hasthorpe H, Mukhtyar C. Revising DAS28 scores for remission in rheumatoid arthritis. Clinical rheumatology [Internet]. 2014 Feb;33(2):269–72. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24384827spa
dc.source.bibliographicCitation60. Pincus T, Swearingen CJ, Bergman M, Yazici Y. RAPID3 (Routine Assessment of Patient Index Data 3), a rheumatoid arthritis index without formal joint counts for routine care: proposed severity categories compared to disease activity score and clinical disease activity index categories. The Journal of rheumatology [Internet]. 2008 Nov;35(11):2136–47. Available from: http://www.ncbi.nlm.nih.gov/pubmed/18793006spa
dc.source.bibliographicCitation61. Shah A, St. Clair EW. Rheumatoid Arthritis. In: Kasper D, Fauci A, Hauser S, Longo D, Jameson JL, Loscalzo J, editors. Harrison’s Principles of Internal Medicine, 19e. New York, NY: McGraw-Hill Education; 2015.spa
dc.source.bibliographicCitation62. Marrie RA, Hitchon CA, Walld R, Patten SB, Bolton JM, Sareen J, et al. Increased Burden of Psychiatric Disorders in Rheumatoid Arthritis. Arthritis care & research [Internet]. 2018 Jul;70(7):970–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/29438604spa
dc.source.bibliographicCitation63. Lisnevskaia L, Murphy G, Isenberg D. Systemic lupus erythematosus. The Lancet [Internet]. 2014 Nov;384(9957):1878–88. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0140673614601288spa
dc.source.bibliographicCitation64. Pons-Estel GJ, Ugarte-Gil MF, Alarcón GS. Epidemiology of systemic lupus erythematosus. Expert Review of Clinical Immunology. 2017;13(8):799–814.spa
dc.source.bibliographicCitation65. Fortuna G, Brennan MT. Systemic Lupus Erythematosus: Epidemiology, Pathophysiology, Manifestations, and Management. Dental Clinics of North America. 2013;57(4):631–55.spa
dc.source.bibliographicCitation66. Hahn BH. Systemic Lupus Erythematosus. In: Kasper D, Fauci A, Hauser S, Longo D, Jameson JL, Loscalzo J, editors. Harrison’s Principles of Internal Medicine, 19e. New York, NY: McGraw-Hill Education; 2015.spa
dc.source.bibliographicCitation67. Anaya J-M, Leon KJ, Rojas M, Rodriguez Y, Pacheco Y, Acosta-Ampudia Y, et al. Progress towards precision medicine for lupus: the role of genetic biomarkers. Expert Review of Precision Medicine and Drug Development [Internet]. 2018 Mar 4;3(2):119–35. Available from: https://www.tandfonline.com/doi/full/10.1080/23808993.2018.1448266spa
dc.source.bibliographicCitation68. James JA, Chen H, Young KA, Bemis EA, Seifert J, Bourn RL, et al. Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients. EBioMedicine. 2019 Apr; In press. Available from: https://www.ncbi.nlm.nih.gov/pubmed/30952617spa
dc.source.bibliographicCitation69. Crow MK. Etiology and Pathogenesis of Systemic Lupus Erythematosus. In: KELLEY’S Textbook of Rheumatology. 9th ed. Philadelphia; 2013. p. 1269–82.spa
dc.source.bibliographicCitation70. Inês L, Silva C, Galindo M, López-Longo FJ, Terroso G, Romão VC, et al. Classification of Systemic Lupus Erythematosus: Systemic Lupus International Collaborating Clinics Versus American College of Rheumatology Criteria. A Comparative Study of 2,055 Patients From a Real-Life, International Systemic Lupus Erythematosus Cohort. Arthritis care & research [Internet]. 2015 Aug;67(8):1180–5. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25581417spa
dc.source.bibliographicCitation71. Karlson EW, Daltroy LH, Rivest C, Ramsey-Goldman R, Wright EA, Partridge AJ, et al. Validation of a Systemic Lupus Activity Questionnaire (SLAQ) for population studies. Lupus [Internet]. 2003;12(4):280–6. Available from: http://www.ncbi.nlm.nih.gov/pubmed/12729051spa
dc.source.bibliographicCitation72. Yu C, Gershwin ME, Chang C. Diagnostic criteria for systemic lupus erythematosus: A critical review. Journal of Autoimmunity [Internet]. 2014 Feb;48–49:10–3. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0896841114000067spa
dc.source.bibliographicCitation73. McElhone K, Abbott J, Teh LS. A review of health related quality of life in systemic lupus erythematosus. Lupus [Internet]. 2006;15(10):633–43. Available from: http://www.ncbi.nlm.nih.gov/pubmed/17120589spa
dc.source.bibliographicCitation74. Schmeding A, Schneider M. Fatigue, health-related quality of life and other patient-reported outcomes in systemic lupus erythematosus. Best practice & research Clinical rheumatology [Internet]. 2013 Jun;27(3):363–75. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24238693spa
dc.source.bibliographicCitation75. Allanore Y, Simms R, Distler O, Trojanowska M, Pope J, Denton CP, et al. Systemic sclerosis. Nature reviews Disease primers [Internet]. 2015 Apr 23;1:15002. Available from: http://www.ncbi.nlm.nih.gov/pubmed/27189141spa
dc.source.bibliographicCitation76. Domsic RT, Rodriguez-Reyna T, Lucas M, Fertig N, Medsger TA. Skin thickness progression rate: a predictor of mortality and early internal organ involvement in diffuse scleroderma. Annals of the rheumatic diseases [Internet]. 2011 Jan;70(1):104–9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/20679474spa
dc.source.bibliographicCitation77. Barnes J, Mayes MD. Epidemiology of systemic sclerosis: incidence, prevalence, survival, risk factors, malignancy, and environmental triggers. Current opinion in rheumatology [Internet]. 2012 Mar;24(2):165–70. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22269658spa
dc.source.bibliographicCitation78. Katsumoto TR, Whitfield ML, Connolly MK. The pathogenesis of systemic sclerosis. Annual review of pathology [Internet]. 2011;6:509–37. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21090968spa
dc.source.bibliographicCitation79. Bhattacharyya S, Wei J, Varga J. Understanding fibrosis in systemic sclerosis: shifting paradigms, emerging opportunities. Nature reviews Rheumatology [Internet]. 2011 Oct 25;8(1):42–54. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22025123spa
dc.source.bibliographicCitation80. Shah AA, Wigley FM. My approach to the treatment of scleroderma. Mayo Clinic proceedings [Internet]. 2013 Apr;88(4):377–93. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23541012spa
dc.source.bibliographicCitation81. van den Hoogen F, Khanna D, Fransen J, Johnson SR, Baron M, Tyndall A, et al. 2013 classification criteria for systemic sclerosis: an American College of Rheumatology/European League against Rheumatism collaborative initiative. Arthritis and rheumatism [Internet]. 2013 Nov;65(11):2737–47. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24122180spa
dc.source.bibliographicCitation82. Man A, Correa JK, Ziemek J, Simms RW, Felson DT, Lafyatis R. Development and validation of a patient-reported outcome instrument for skin involvement in patients with systemic sclerosis. Annals of the rheumatic diseases [Internet]. 2017 Aug;76(8):1374–80. Available from: http://www.ncbi.nlm.nih.gov/pubmed/28213563spa
dc.source.bibliographicCitation83. Rojas M, Rodriguez Y, Pacheco Y, Zapata E, Monsalve DM, Mantilla RD, et al. Resilience in women with autoimmune rheumatic diseases. Joint, bone, spine [Internet]. 2018 Dec;85(6):715–20. Available from: http://www.ncbi.nlm.nih.gov/pubmed/29289647spa
dc.source.bibliographicCitation84. Kallenberg CG, Wouda AA, Hoet MH, van Venrooij WJ. Development of connective tissue disease in patients presenting with Raynaud’s phenomenon: a six year follow up with emphasis on the predictive value of antinuclear antibodies as detected by immunoblotting. Annals of the rheumatic diseases [Internet]. 1988 Aug;47(8):634–41. Available from: http://www.ncbi.nlm.nih.gov/pubmed/3261966spa
dc.source.bibliographicCitation85. Weiner ES, Hildebrandt S, Senécal JL, Daniels L, Noell S, Joyal F, et al. Prognostic significance of anticentromere antibodies and anti-topoisomerase I antibodies in Raynaud’s disease. A prospective study. Arthritis and rheumatism [Internet]. 1991 Jan;34(1):68–77. Available from: http://www.ncbi.nlm.nih.gov/pubmed/1845841spa
dc.source.bibliographicCitation86. Baubet T, Brunet M, Garcia De La Peña-Lefebvre P, Taïeb O, Moro M-R, Guillevin L, et al. [Psychiatric manifestations of systemic sclerosis]. Annales de medecine interne [Internet]. 2002 Jun;153(4):237–41. Available from: http://www.ncbi.nlm.nih.gov/pubmed/12218889spa
dc.source.bibliographicCitation87. Mura G, Bhat KM, Pisano A, Licci G, Carta M. Psychiatric symptoms and quality of life in systemic sclerosis. Clinical practice and epidemiology in mental health : CP & EMH. 2012;8:30–5.spa
dc.source.bibliographicCitation88. Nakayama A, Tunnicliffe DJ, Thakkar V, Singh-Grewal D, O’Neill S, Craig JC, et al. Patients’ perspectives and experiences living with systemic sclerosis: A systematic review and thematic synthesis of qualitative studies. Journal of Rheumatology. 2016;43(7):1363–75.spa
dc.source.bibliographicCitation89. Nguyen C, Ranque B, Baubet T, Bérezné A, Mestre-Stanislas C, Rannou F, et al. Clinical, functional and health-related quality of life correlates of clinically significant symptoms of anxiety and depression in patients with systemic sclerosis: a cross-sectional survey. PloS one [Internet]. 2014;9(2):e90484. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24587375spa
dc.source.bibliographicCitation90. Straszecka J, Kucharz EJ, Jonderko G, Kotulska A, Bednarczyk-Kaluzny M, Brzezinska-Wcislo L, et al. Depression and anxiety in patients with systemic sclerosis. Vol. 15, Clinical rheumatology. Germany; 1996. p. 621.spa
dc.source.bibliographicCitation91. Ostojic P, Zivojinovic S, Reza T, Damjanov N. Symptoms of depression and anxiety in Serbian patients with systemic sclerosis: impact of disease severity and socioeconomic factors. Modern rheumatology [Internet]. 2010 Aug;20(4):353–7. Available from: http://www.ncbi.nlm.nih.gov/pubmed/20336476spa
dc.source.bibliographicCitation92. Thombs BD, Jewett LR, Kwakkenbos L, Hudson M, Baron M, Canadian Scleroderma Research Group. Major depression diagnoses among patients with systemic sclerosis: baseline and one-month followup. Arthritis care & research [Internet]. 2015 Mar;67(3):411–6. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25156077spa
dc.source.bibliographicCitation93. Hudson M, Thombs BD, Steele R, Panopalis P, Newton E, Baron M, et al. Quality of life in patients with systemic sclerosis compared to the general population and patients with other chronic conditions. The Journal of rheumatology [Internet]. 2009 Apr;36(4):768–72. Available from: http://www.ncbi.nlm.nih.gov/pubmed/19228662spa
dc.source.bibliographicCitation94. Benrud-Larson LM, Haythornthwaite JA, Heinberg LJ, Boling C, Reed J, White B, et al. The impact of pain and symptoms of depression in scleroderma. Pain [Internet]. 2002 Feb;95(3):267–75. Available from: http://www.ncbi.nlm.nih.gov/pubmed/11839426spa
dc.source.bibliographicCitation95. Anaya J-M. ¿Qué es el síndrome de Sjögren y por qué es importante? In: Síndrome de Sjögren. 2nd ed. Bogotá; 2017. p. 3–10.spa
dc.source.bibliographicCitation96. Moutsopoulos HM, Tzioufas AG. Sjögren Syndrome. In: Kasper D, Fauci A, Hauser S, Longo D, Jameson JL, Loscalzo J, editors. Harrison’s Principles of Internal Medicine, 19e. New York, NY: McGraw-Hill Education; 2015.spa
dc.source.bibliographicCitation97. Castiblanco-Torres JL, Rojas-villarraga A. Anatomía y fisiología de las glándulas salivales. In: Síndrome de Sjögren. 2nd ed. Bogotá; 2017. p. 27–38.spa
dc.source.bibliographicCitation98. Mavragani CP, Moutsopoulos NM, Moutsopoulos HM. The management of Sjögren’s syndrome. Nature clinical practice Rheumatology [Internet]. 2006 May;2(5):252–61. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16932698spa
dc.source.bibliographicCitation99. Goules A V, Tzioufas AG, Moutsopoulos HM. Classification criteria of Sjögren’s syndrome. Journal of autoimmunity [Internet]. 2014;48–49(2014):42–5. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24456935spa
dc.source.bibliographicCitation100. Seror R, Theander E, Brun JG, Ramos-Casals M, Valim V, Dörner T, et al. Validation of EULAR primary Sjögren’s syndrome disease activity (ESSDAI) and patient indexes (ESSPRI). Annals of the rheumatic diseases [Internet]. 2015 May;74(5):859–66. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24442883spa
dc.source.bibliographicCitation101. Ramos-Casals M, Brito-Zerón P, Sisó-Almirall A, Bosch X. Primary Sjogren syndrome. BMJ [Internet]. 2012 Jun 14;344(jun14 1):e3821. Available from: http://www.bmj.com/cgi/doi/10.1136/bmj.e3821spa
dc.source.bibliographicCitation102. Milin M, Cornec D, Chastaing M, Griner V, Berrouiguet S, Nowak E, et al. Sicca symptoms are associated with similar fatigue, anxiety, depression, and quality-of-life impairments in patients with and without primary Sjogren’s syndrome. Joint, bone, spine. 2016 Dec;83(6):681–5.spa
dc.source.bibliographicCitation103. Lorton D, Lubahn CL, Zautra AJ, Bellinger DL. Proinflammatory cytokines and sickness behavior in rheumatic diseases. Current Pharmaceutical Design. 2008;14(13):1242–60.spa
dc.source.bibliographicCitation104. Connor KM, Davidson JRT. Development of a new resilience scale: the Connor-Davidson Resilience Scale (CD-RISC). Depression and anxiety [Internet]. 2003;18(2):76–82. Available from: http://www.ncbi.nlm.nih.gov/pubmed/12964174spa
dc.source.bibliographicCitation105. Masten AS. Ordinary magic. Resilience processes in development. The American psychologist [Internet]. 2001 Mar;56(3):227–38. Available from: http://www.ncbi.nlm.nih.gov/pubmed/11315249spa
dc.source.bibliographicCitation106. Luthar SS, Cicchetti D, Becker B. The construct of resilience: a critical evaluation and guidelines for future work. Child development [Internet]. 2000;71(3):543–62. Available from: http://www.ncbi.nlm.nih.gov/pubmed/10953923spa
dc.source.bibliographicCitation107. Feder A, Nestler EJ, Charney DS. Psychobiology and molecular genetics of resilience. Nature reviews Neuroscience. 2009 Jun;10(6):446–57.spa
dc.source.bibliographicCitation108. Friedman AK, Walsh JJ, Juarez B, Ku SM, Chaudhury D, Wang J, et al. Enhancing depression mechanisms in midbrain dopamine neurons achieves homeostatic resilience. Science [Internet]. 2014 Apr 18;344(6181):313–9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24744379spa
dc.source.bibliographicCitation109. Liu H, Zhang C, Ji Y, Yang L. Biological and Psychological Perspectives of Resilience: Is It Possible to Improve Stress Resistance? Frontiers in human neuroscience [Internet]. 2018;12:326. Available from: http://www.ncbi.nlm.nih.gov/pubmed/30186127spa
dc.source.bibliographicCitation110. Ahern NR, Kiehl EM, Sole M Lou, Byers J. A review of instruments measuring resilience. Issues in comprehensive pediatric nursing [Internet]. 2006;29(2):103–25. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16772239spa
dc.source.bibliographicCitation111. Evers AWM, Zautra A, Thieme K. Stress and resilience in rheumatic diseases: A review and glimpse into the future. Nature Reviews Rheumatology. 2011;7(7):409–15.spa
dc.source.bibliographicCitation112. Wohleb ES, Franklin T, Iwata M, Duman RS. Integrating neuroimmune systems in the neurobiology of depression. Nature reviews Neuroscience [Internet]. 2016;17(8):497–511. Available from: http://www.ncbi.nlm.nih.gov/pubmed/27277867spa
dc.source.bibliographicCitation113. Kavelaars A, Heijnen CJ. Stress, genetics, and immunity. Brain, Behavior, and Immunity [Internet]. 2006 Jul;20(4):313–6. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16495034spa
dc.source.bibliographicCitation114. Ménard C, Pfau ML, Hodes GE, Russo SJ. Immune and Neuroendocrine Mechanisms of Stress Vulnerability and Resilience. Neuropsychopharmacology. 2017;42(1):62–80.spa
dc.source.bibliographicCitation115. Carmichael O, Lockhart S. The role of diffusion tensor imaging in the study of cognitive aging. Current topics in behavioral neurosciences [Internet]. 2012;11(November 2011):289–320. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22081443spa
dc.source.bibliographicCitation116. Irwin M. Psychoneuroimmunology of depression: Clinical implications. Brain, Behavior, and Immunity. 2002;16(1):1–16.spa
dc.source.bibliographicCitation117. Elenkov IJ, Chrousos GP. Stress hormones, proinflammatory and antiinflammatory cytokines, and autoimmunity. Annals of the New York Academy of Sciences [Internet]. 2002 Jun;966(1):290–303. Available from: http://www.ncbi.nlm.nih.gov/pubmed/12114286spa
dc.source.bibliographicCitation118. Silverman MN, Deuster PA. Biological mechanisms underlying the role of physical fitness in health and resilience. Interface focus [Internet]. 2014 Oct 6;4(5):20140040. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25285199spa
dc.source.bibliographicCitation119. Childs E, de Wit H. Regular exercise is associated with emotional resilience to acute stress in healthy adults. Frontiers in physiology [Internet]. 2014;5(May):161. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24822048spa
dc.source.bibliographicCitation120. Baratta M V, Rozeske RR, Maier SF. Understanding stress resilience. Frontiers in behavioral neuroscience [Internet]. 2013 Feb;7:158. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24265608spa
dc.source.bibliographicCitation121. Bartone PT, Ursano RJ, Wright KM, Ingraham LH. The impact of a military air disaster on the health of assistance workers. A prospective study. The Journal of nervous and mental disease. 1989 Jun;177(6):317–28.spa
dc.source.bibliographicCitation122. Wagnild GM, Young HM. Development and psychometric evaluation of the Resilience Scale. Journal of nursing measurement [Internet]. 1993;1(2):165–78. Available from: http://www.ncbi.nlm.nih.gov/pubmed/7850498spa
dc.source.bibliographicCitation123. Smith BW, Epstein EM, Ortiz JA, Christopher PJ, Tooley EM. The Foundations of Resilience: What Are the Critical Resources for Bouncing Back from Stress? In: Prince-Embury S, Saklofske DH, editors. Resilience in Children, Adolescents, and Adults: Translating Research into Practice. New York, NY: Springer New York; 2013. p. 167–87.spa
dc.source.bibliographicCitation124. Rodríguez-Rey R, Alonso-Tapia J, Hernansaiz-Garrido H. Reliability and validity of the Brief Resilience Scale (BRS) Spanish Version. Psychological assessment [Internet]. 2016 May;28(5):e101–10. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26502199spa
dc.source.bibliographicCitation125. Bartley EJ, Hossain NI, Gravlee CC, Sibille KT, Terry EL, Vaughn IA, et al. Race/Ethnicity Moderates the Association Between Psychosocial Resilience and Movement-Evoked Pain in Knee Osteoarthritis. ACR Open Rheumatology. 2019;1(1):16–25.spa
dc.source.bibliographicCitation126. Faria DAP, Revoredo LS, Vilar MJ, Eulália Maria Chaves M. Resilience and treatment adhesion in patients with systemic lupus erythematosus. The open rheumatology journal [Internet]. 2014;8(1):1–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24665352spa
dc.source.bibliographicCitation127. Tan-Kristanto S, Kiropoulos LA. Resilience, self-efficacy, coping styles and depressive and anxiety symptoms in those newly diagnosed with multiple sclerosis. Psychology, health & medicine [Internet]. 2015 Oct;20(6):635–45. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25588098spa
dc.source.bibliographicCitation128. Azizoddin DR, Zamora-Racaza G, Ormseth SR, Sumner LA, Cost C, Ayeroff JR, et al. Psychological Factors that Link Socioeconomic Status to Depression/Anxiety in Patients with Systemic Lupus Erythematosus. Journal of clinical psychology in medical settings [Internet]. 2017 Dec;24(3–4):302–15. Available from: http://www.ncbi.nlm.nih.gov/pubmed/28776205spa
dc.source.bibliographicCitation129. Rosemberg M-AS, Li Y, Seng J. Allostatic load: a useful concept for advancing nursing research. Journal of clinical nursing [Internet]. 2017 Dec;26(23–24):5191–205. Available from: http://www.ncbi.nlm.nih.gov/pubmed/28177541spa
dc.source.bibliographicCitation130. Herrmann M, Scholmerich J, Straub RH. Stress and rheumatic diseases. Rheumatic Disease Clinics of North America. 2000;26(4):737–63.spa
dc.source.bibliographicCitation131. Battalio SL, Silverman AM, Ehde DM, Amtmann D, Edwards KA, Jensen MP. Resilience and Function in Adults With Physical Disabilities: An Observational Study. Archives of physical medicine and rehabilitation [Internet]. 2017 Jun;98(6):1158–64. Available from: http://www.ncbi.nlm.nih.gov/pubmed/27993585spa
dc.source.bibliographicCitation132. Nakazawa K, Noda T, Ichikura K, Okamoto T, Takahashi Y, Yamamura T, et al. Resilience and depression/anxiety symptoms in multiple sclerosis and neuromyelitis optica spectrum disorder. Multiple sclerosis and related disorders [Internet]. 2018 Oct;25:309–15. Available from: http://www.ncbi.nlm.nih.gov/pubmed/30176401spa
dc.source.bibliographicCitation133. Silverman AM, Verrall AM, Alschuler KN, Smith AE, Ehde DM. Bouncing back again, and again: a qualitative study of resilience in people with multiple sclerosis. Disability and rehabilitation [Internet]. 2017 Feb;39(1):14–22. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26878245spa
dc.source.bibliographicCitation134. Strand EB, Zautra AJ, Thoresen M, Ødegård S, Uhlig T, Finset A. Positive affect as a factor of resilience in the pain-negative affect relationship in patients with rheumatoid arthritis. Journal of psychosomatic research [Internet]. 2006 May;60(5):477–84. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16650588spa
dc.source.bibliographicCitation135. Réus GZ, Moura AB de, Silva RH, Quevedo WRR and J. Resilience dysregulation in major depressive disorder: focus on glutamatergic imbalance and microglial activation. Vol. 15, Current Neuropharmacology. 2017. p. 1.spa
dc.source.bibliographicCitation136. Alschuler KN, Arewasikporn A, Nelson IK, Molton IR, Ehde DM. Promoting resilience in individuals aging with multiple sclerosis: Results from a pilot randomized controlled trial. Rehabilitation psychology. 2018 Aug;63(3):338–48spa
dc.source.bibliographicCitation137. Quiceno JM, Vinaccia S, Remor E. Empowerment program of resilience for rheumatoid arthritis patients. Revista de Psicopatología y Psicología Clínica. 2014;16(1):27.spa
dc.source.bibliographicCitation138. Green SB. How Many Subjects Does It Take To Do A Regression Analysis. Multivariate behavioral research. 1991 Jul;26(3):499–510.spa
dc.source.bibliographicCitation139. Franco J-S, Amaya-Amaya J, Molano-González N, Caro-Moreno J, Rodríguez-Jiménez M, Acosta-Ampudia Y, et al. Autoimmune thyroid disease in Colombian patients with systemic lupus erythematosus. Clinical endocrinology [Internet]. 2015 Dec;83(6):943–50. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25382266spa
dc.source.bibliographicCitation140. Rojas M, Rodríguez Y, Monsalve DM, Pacheco Y, Acosta-Ampudia Y, Rodríguez-Jimenez M, et al. Cytokine imbalance in patients with systemic sclerosis and resilience: the key role of interleukin-6. Clinical and experimental rheumatology [Internet]. 2019 Jan 10; Available from: http://www.ncbi.nlm.nih.gov/pubmed/30652681spa
dc.source.bibliographicCitation141. Rodriguez Y, Ramírez-Santana C, Molano-González N, Anaya J-M, Rojas M, Monsalve DM, et al. Autoimmune Thyroid Disease In Euthyroid Subjects. Universidad del Rosario; 2018.spa
dc.source.bibliographicCitation142. Tunnicliffe DJ, Singh-Grewal D, Chaitow J, Mackie F, Manolios N, Lin M-W, et al. Lupus Means Sacrifices: Perspectives of Adolescents and Young Adults With Systemic Lupus Erythematosus. Arthritis care & research [Internet]. 2016 Jun;68(6):828–37. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26414860spa
dc.source.bibliographicCitation143. Hargardóttir H, van Helvoort HAC, Vonk MC, van den Hoogen FHJ, Dekhuijzen PNR, Heijdra YF. Exercise in systemic sclerosis intensifies systemic inflammation and oxidative stress. Scandinavian journal of rheumatology [Internet]. 2010;39(1):63–70. Available from: http://www.ncbi.nlm.nih.gov/pubmed/20132073spa
dc.source.bibliographicCitation144. Azar M, Rice DB, Kwakkenbos L, Carrier M-E, Shrier I, Bartlett SJ, et al. Exercise habits and factors associated with exercise in systemic sclerosis: a Scleroderma Patient-centered Intervention Network (SPIN) cohort study. Disability and rehabilitation [Internet]. 2018 May;40(17):1997–2003. Available from: http://www.ncbi.nlm.nih.gov/pubmed/28478701spa
dc.source.bibliographicCitation145. Rannou F, Boutron I, Mouthon L, Sanchez K, Tiffreau V, Hachulla E, et al. Personalized Physical Therapy Versus Usual Care for Patients With Systemic Sclerosis: A Randomized Controlled Trial. Arthritis care & research [Internet]. 2017 Jul;69(7):1050–9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/27696703spa
dc.source.bibliographicCitation146. Hudson M, Rojas-Villarraga A, Coral-Alvarado P, López-Guzmán S, Mantilla RD, Chalem P, et al. Polyautoimmunity and familial autoimmunity in systemic sclerosis. Journal of Autoimmunity [Internet]. 2008 Sep;31(2):156–9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/18644698spa
dc.source.bibliographicCitation147. Molano-González N, Rojas M, Monsalve DM, Pacheco Y, Acosta-Ampudia Y, Rodríguez Y, et al. Cluster analysis of autoimmune rheumatic diseases based on autoantibodies. New insights for polyautoimmunity. Journal of autoimmunity [Internet]. 2019 Mar;98:24–32. Available from: http://www.ncbi.nlm.nih.gov/pubmed/30459097spa
dc.source.bibliographicCitation148. Moinzadeh P, Aberer E, Ahmadi-Simab K, Blank N, Distler JHW, Fierlbeck G, et al. Disease progression in systemic sclerosis-overlap syndrome is significantly different from limited and diffuse cutaneous systemic sclerosis. Annals of the rheumatic diseases [Internet]. 2015 Apr;74(4):730–7. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24389298spa
dc.source.bibliographicCitation149. Zhu M, Liang Z, Wang T, Chen R, Wang G, Ji Y. Th1/Th2/Th17 cells imbalance in patients with asthma with and without psychological symptoms. Allergy and asthma proceedings [Internet]. 2016;37(2):148–56. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26932172spa
dc.source.bibliographicCitation150. Köhler CA, Freitas TH, Maes M, de Andrade NQ, Liu CS, Fernandes BS, et al. Peripheral cytokine and chemokine alterations in depression: a meta-analysis of 82 studies. Acta psychiatrica Scandinavica [Internet]. 2017 May;135(5):373–87. Available from: http://www.ncbi.nlm.nih.gov/pubmed/28122130spa
dc.source.bibliographicCitation151. Kurzinski K, Torok KS. Cytokine profiles in localized scleroderma and relationship to clinical features. Cytokine [Internet]. 2011 Aug;55(2):157–64. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21536453spa
dc.source.bibliographicCitation152. Elomaa A-P, Niskanen L, Herzig K-H, Viinamäki H, Hintikka J, Koivumaa-Honkanen H, et al. Elevated levels of serum IL-5 are associated with an increased likelihood of major depressive disorder. BMC psychiatry [Internet]. 2012 Jan 9;12:2. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22230487spa
dc.source.bibliographicCitation153. Valkanova V, Ebmeier KP, Allan CL. CRP, IL-6 and depression: a systematic review and meta-analysis of longitudinal studies. Journal of affective disorders [Internet]. 2013 Sep 25;150(3):736–44. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23870425spa
dc.source.bibliographicCitation154. Brydon L, Walker C, Wawrzyniak AJ, Chart H, Steptoe A. Dispositional optimism and stress-induced changes in immunity and negative mood. Brain, behavior, and immunity. 2009 Aug;23(6):810–6.spa
dc.source.bibliographicCitation155. Maes M, Bosmans E, De Jongh R, Kenis G, Vandoolaeghe E, Neels H. Increased serum IL-6 and IL-1 receptor antagonist concentrations in major depression and treatment resistant depression. Cytokine [Internet]. 1997 Nov;9(11):853–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/9367546spa
dc.source.bibliographicCitation156. Su S, Miller AH, Snieder H, Bremner JD, Ritchie J, Maisano C, et al. Common Genetic Contributions to Depressive Symptoms and Inflammatory Markers in Middle-Aged Men: The Twins Heart Study. Psychosomatic Medicine [Internet]. 2009 Feb;71(2):152–8. Available from: https://insights.ovid.com/crossref?an=00006842-200902000-00003spa
dc.source.bibliographicCitation157. Maes M, Anderson G, Kubera M, Berk M. Targeting classical IL-6 signalling or IL-6 trans-signalling in depression? Expert opinion on therapeutic targets [Internet]. 2014 May;18(5):495–512. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24548241spa
dc.source.bibliographicCitation158. Frommberger UH, Bauer J, Haselbauer P, Fräulin A, Riemann D, Berger M. Interleukin-6-(IL-6) plasma levels in depression and schizophrenia: comparison between the acute state and after remission. European archives of psychiatry and clinical neuroscience [Internet]. 1997;247(4):228–33. Available from: http://www.ncbi.nlm.nih.gov/pubmed/9332905spa
dc.source.bibliographicCitation159. Kubera M, Kenis G, Bosmans E, Kajta M, Basta-Kaim A, Scharpe S, et al. Stimulatory effect of antidepressants on the production of IL-6. International immunopharmacology [Internet]. 2004 Feb;4(2):185–92. Available from: http://www.ncbi.nlm.nih.gov/pubmed/14996410spa
dc.source.bibliographicCitation160. Dürk T, Panther E, Müller T, Sorichter S, Ferrari D, Pizzirani C, et al. 5-Hydroxytryptamine modulates cytokine and chemokine production in LPS-primed human monocytes via stimulation of different 5-HTR subtypes. International immunology [Internet]. 2005 May;17(5):599–606. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15802305spa
dc.source.bibliographicCitation161. Pinho de Oliveira Ribeiro N, Rafael de Mello Schier A, Ornelas AC, Pinho de Oliveira CM, Nardi AE, Silva AC. Anxiety, depression and suicidal ideation in patients with rheumatoid arthritis in use of methotrexate, hydroxychloroquine, leflunomide and biological drugs. Comprehensive psychiatry [Internet]. 2013 Nov;54(8):1185–9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23829886spa
dc.source.bibliographicCitation162. Abdel-Magied RA, Kamel SR, Said AF, Ali HM, Abdel Gawad EA, Moussa MM. Serum interleukin-6 in systemic sclerosis and its correlation with disease parameters and cardiopulmonary involvement. Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG [Internet]. 2016 Dec 23;33(4):321–30. Available from: http://www.ncbi.nlm.nih.gov/pubmed/28079844spa
dc.source.bibliographicCitation163. Sato S, Hasegawa M, Takehara K. Serum levels of interleukin-6 and interleukin-10 correlate with total skin thickness score in patients with systemic sclerosis. Journal of dermatological science [Internet]. 2001 Oct;27(2):140–6. Available from: http://www.ncbi.nlm.nih.gov/pubmed/11532378spa
dc.source.bibliographicCitation164. Matsushita T, Hasegawa M, Hamaguchi Y, Takehara K, Sato S. Longitudinal analysis of serum cytokine concentrations in systemic sclerosis: association of interleukin 12 elevation with spontaneous regression of skin sclerosis. The Journal of rheumatology [Internet]. 2006 Feb;33(2):275–84. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16465658spa
dc.source.bibliographicCitation165. Khanna D, Denton CP, Lin CJF, van Laar JM, Frech TM, Anderson ME, et al. Safety and efficacy of subcutaneous tocilizumab in systemic sclerosis: results from the open-label period of a phase II randomised controlled trial (faSScinate). Annals of the rheumatic diseases [Internet]. 2018 Feb;77(2):212–20. Available from: http://www.ncbi.nlm.nih.gov/pubmed/29066464spa
dc.source.bibliographicCitation166. Zou G, Li Y, Xu R, Li P. Resilience and positive affect contribute to lower cancer-related fatigue among Chinese patients with gastric cancer. Journal of clinical nursing [Internet]. 2018 Apr;27(7–8):e1412–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/29266530spa
dc.source.bibliographicCitation167. Bruunsgaard H, Galbo H, Halkjaer-Kristensen J, Johansen TL, MacLean DA, Pedersen BK. Exercise-induced increase in serum interleukin-6 in humans is related to muscle damage. The Journal of physiology. 1997 Mar;499:833–41.spa
dc.source.bibliographicCitation168. Steensberg A, Fischer CP, Keller C, Møller K, Pedersen BK. IL-6 enhances plasma IL-1ra, IL-10, and cortisol in humans. American journal of physiology Endocrinology and metabolism [Internet]. 2003 Aug;285(2):E433-7. Available from: http://www.ncbi.nlm.nih.gov/pubmed/12857678spa
dc.source.bibliographicCitation169. Sharif K, Watad A, Bragazzi NL, Lichtbroun M, Amital H, Shoenfeld Y. Physical activity and autoimmune diseases: Get moving and manage the disease. Autoimmunity reviews [Internet]. 2018 Jan;17(1):53–72. Available from: http://www.ncbi.nlm.nih.gov/pubmed/29108826spa
dc.source.bibliographicCitation170. Resnick B, Klinedinst NJ, Yerges-Armstrong L, Choi EY, Dorsey SG. The Impact of Genetics on Physical Resilience and Successful Aging. Journal of aging and health [Internet]. 2015 Sep;27(6):1084–104. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25818147spa
dc.source.bibliographicCitation171. Epel ES, Lin J, Wilhelm FH, Wolkowitz OM, Cawthon R, Adler NE, et al. Cell aging in relation to stress arousal and cardiovascular disease risk factors. Psychoneuroendocrinology [Internet]. 2006 Apr;31(3):277–87. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16298085spa
dc.source.bibliographicCitation172. Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT, Bingham CO, et al. 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Arthritis and rheumatism [Internet]. 2010 Sep;62(9):2569–81. Available from: http://www.ncbi.nlm.nih.gov/pubmed/20872595spa
dc.source.bibliographicCitation173. Turesson C, Matteson EL. Cardiovascular risk factors, fitness and physical activity in rheumatic diseases. Current opinion in rheumatology. 2007 Mar;19(2):190–6.spa
dc.source.bibliographicCitation174. Holdsworth SR, Gan P-Y. Cytokines: Names and Numbers You Should Care About. Clinical journal of the American Society of Nephrology : CJASN [Internet]. 2015 Dec 7;10(12):2243–54. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25941193spa
dc.source.bibliographicCitation175. Brüggemann M, Osborn MJ, Ma B, Hayre J, Avis S, Lundstrom B, et al. Human antibody production in transgenic animals. Archivum immunologiae et therapiae experimentalis [Internet]. 2015 Apr;63(2):101–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25467949spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subjectResiliencespa
dc.subjectRheumatoid arthritisspa
dc.subjectSystemic lupus erythematosusspa
dc.subjectSystemic sclerosisspa
dc.subjectSjögren’s síndromespa
dc.subject.ddcEnfermedadesspa
dc.subject.lembArtritis reumatoidespa
dc.subject.lembLupus eritematoso sistémicospa
dc.subject.lembEsclerodermia Sistémicaspa
dc.subject.lembSíndrome de Sjögrenspa
dc.titleThe role of clinical, biological, and socioeconomic factors on the development of resilience in women with autorimmune rheumatic diseases : a cross-sectional studyspa
dc.typemasterThesiseng
dc.type.documentTesisspa
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion
dc.type.spaTesis de maestríaspa
local.department.reportEscuela de Medicina y Ciencias de la Saludspa
Archivos
Bloque original
Mostrando1 - 5 de 6
Cargando...
Miniatura
Nombre:
Resilience_MERQ_2019-1_Revisado.pdf
Tamaño:
1.57 MB
Formato:
Adobe Portable Document Format
Descripción:
Tesis Resiliencia - MERQ
Cargando...
Miniatura
Nombre:
Appendix 2.pdf
Tamaño:
257.74 KB
Formato:
Adobe Portable Document Format
Descripción:
Appendix 2
Cargando...
Miniatura
Nombre:
Appendix 3.pdf
Tamaño:
756.58 KB
Formato:
Adobe Portable Document Format
Descripción:
Appendix 3
Cargando...
Miniatura
Nombre:
Appendix 4.pdf
Tamaño:
64.36 KB
Formato:
Adobe Portable Document Format
Descripción:
Appendix 4
Cargando...
Miniatura
Nombre:
Appendix 5.pdf
Tamaño:
343.81 KB
Formato:
Adobe Portable Document Format
Descripción:
Appendix 5