Ítem
Solo Metadatos

Situation awareness performance in healthy young adults is associated with a serotonin transporter gene polymorphism

Mostrar el registro sencillo de la publicación
dc.creatorGonzález-Giraldo, Yeimyspa
dc.creatorGonzález Reyes, Rodrigo Estebanspa
dc.creatorMueller, Shane T.spa
dc.creatorPiper, Brian J.spa
dc.creatorAdan, Anaspa
dc.creatorGarzon-Forero, Diego Aspa
dc.date.accessioned2020-08-19T14:40:36Z
dc.date.available2020-08-19T14:40:36Z
dc.date.created2017-11-10spa
dc.description.abstractBackground Situation awareness (SA) is defined in three levels: SA1 is the perception of the elements in a specific context, SA2 is the comprehension of their meaning, and SA3 is the projection of their status. Purpose To analyze the possible association of a genetic polymorphism in the serotonin transporter (SLC6A4) gene and performance on the Situational Awareness test (SAtest). Methods SAtest was applied to a sample of 230 healthy Colombian subjects, using the Psychology Experiment Building Language platform and a functional polymorphism in the SLC6A4 gene was genotyped by polymerase chain reaction. Results In the SA1 level, s/s genotype carriers had worse accuracy, in comparison with s/l and l/l genotypes. At SA2 level, l/l genotype carriers had better accuracy than s/s and s/l individuals and that in the SA3 level, l/l carriers also had better accuracy. These associations were significant after correction for multiple testing. Conclusions It is possible that l/l carriers have a better ability to perceive and focus their attention on the elements of their environment and to have the capacity to understand and predict what will happen with those elements. This is the first genetic study of SA performance in healthy participants. Additional investigations of other genes could contribute to the understanding of the molecular correlates of SA in healthy subjects and in neuropsychiatric patients.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1177/0033294117740136
dc.identifier.issnISSN: 0033-2941
dc.identifier.issnEISSN: 1558-691X
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/26955
dc.language.isoengspa
dc.publisherSAGE Publicationsspa
dc.relation.citationEndPage891
dc.relation.citationIssueNo. 12
dc.relation.citationStartPage877
dc.relation.citationTitlePsychological Reports
dc.relation.citationVolumeVol. 121
dc.relation.ispartofPsychological Reports, ISSN: 0033-2941;EISSN: 1558-691X, Vol.121, No.12 (2018); pp. 877-891spa
dc.relation.urihttps://journals.sagepub.com/doi/abs/10.1177/0033294117740136?journalCode=prxaspa
dc.rights.accesRightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.accesoRestringido (Acceso a grupos específicos)spa
dc.sourcePsychological Reportsspa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.keywordNeurogeneticsspa
dc.subject.keywordCandidate genesspa
dc.subject.keywordWorking memoryspa
dc.subject.keywordSituation awarenessspa
dc.subject.keywordSerotoninspa
dc.subject.keywordPsychiatric geneticsspa
dc.titleSituation awareness performance in healthy young adults is associated with a serotonin transporter gene polymorphismspa
dc.title.TranslatedTitleEl rendimiento de la conciencia de la situación en adultos jóvenes sanos se asocia con un polimorfismo del gen transportador de serotoninaspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
Archivos
Colecciones
Artículos