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Toxoplasma gondii: P30 peptides recognition pattern in human toxoplasmosis

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dc.creatorCardona, Nestorspa
dc.creatorde-la-Torre, Alejandraspa
dc.creatorSiachoque, Heberspa
dc.creatorPatarroyo, Manuel A.spa
dc.creatorGomez-Marin, Jorge E.spa
dc.date.accessioned2020-05-26T00:07:53Z
dc.date.available2020-05-26T00:07:53Z
dc.date.created2009spa
dc.description.abstractIn this study, human sera reactivity against nine peptides derived from the Toxoplasma gondii P30 protein was assessed by ELISA in patients with different clinical forms of toxoplasmosis. Same as has been reported in mice, sera from congenital, ocular and chronic asymptomatic toxoplasmosis patients recognized more strongly peptides from the protein's carboxy-terminus, being peptide 2017 (amino acids 301-320) the one most strongly recognized by sera from patients with ocular toxoplasmosis. Serum samples collected from 13 patients without ocular infection, 13 with inactive chorioretinal scars, 6 with active ocular infection and 10 seronegative individuals were then screened for anti-2017 IgG. Peptide 2017 was recognized by all patients' samples but not by sera from T. gondii-seronegative individuals. No statistically significant differences were found between the absorbance levels of groups with and without lesions or with active or inactive ocular lesions, as determined by ANOVA. © 2009 Elsevier Inc. All rights reserved.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.exppara.2009.06.017
dc.identifier.issn00144894
dc.identifier.issn10902449
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/24038
dc.language.isoengspa
dc.relation.citationEndPage202
dc.relation.citationIssueNo. 2
dc.relation.citationStartPage199
dc.relation.citationTitleExperimental Parasitology
dc.relation.citationVolumeVol. 123
dc.relation.ispartofExperimental Parasitology, ISSN:00144894, 10902449, Vol.123, No.2 (2009); pp. 199-202spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-68949194535&doi=10.1016%2fj.exppara.2009.06.017&partnerID=40&md5=788f653187ebbfdb3ef4d0afb39dedbcspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordImmunoglobulin G antibodyspa
dc.subject.keywordProtein p30spa
dc.subject.keywordSurfaceeng
dc.subject.keywordProtozoaneng
dc.subject.keywordOculareng
dc.subject.keywordCongenitaleng
dc.subject.keywordArticlespa
dc.subject.keywordCarboxy terminal sequencespa
dc.subject.keywordChorioretinopathyspa
dc.subject.keywordClinical articlespa
dc.subject.keywordCongenital toxoplasmosisspa
dc.subject.keywordControlled studyspa
dc.subject.keywordEye infectionspa
dc.subject.keywordHumanspa
dc.subject.keywordHumoral immunityspa
dc.subject.keywordInfantspa
dc.subject.keywordMolecular recognitionspa
dc.subject.keywordNonhumanspa
dc.subject.keywordNucleotide sequencespa
dc.subject.keywordParasite immunityspa
dc.subject.keywordPriority journalspa
dc.subject.keywordToxoplasma gondiispa
dc.subject.keywordToxoplasmosisspa
dc.subject.keywordAmino Acid Sequencespa
dc.subject.keywordAnalysis of Variancespa
dc.subject.keywordAnimalsspa
dc.subject.keywordAntigenseng
dc.subject.keywordAntigenseng
dc.subject.keywordChronic Diseasespa
dc.subject.keywordEnzyme-Linked Immunosorbent Assayspa
dc.subject.keywordHumansspa
dc.subject.keywordImmune Seraspa
dc.subject.keywordImmunoglobulin Gspa
dc.subject.keywordInfantspa
dc.subject.keywordMolecular Sequence Dataspa
dc.subject.keywordPeptidesspa
dc.subject.keywordProtozoan Proteinsspa
dc.subject.keywordToxoplasmaspa
dc.subject.keywordToxoplasmosisspa
dc.subject.keywordToxoplasmosiseng
dc.subject.keywordToxoplasmosiseng
dc.subject.keywordMusspa
dc.subject.keywordToxoplasma gondiispa
dc.subject.keywordHuman antibodiesspa
dc.subject.keywordPeptidesspa
dc.subject.keywordSAG1spa
dc.subject.keywordToxoplasma gondiispa
dc.titleToxoplasma gondii: P30 peptides recognition pattern in human toxoplasmosisspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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