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Cardiovascular disease in latin american patients with systemic lupus erythematosus: a cross-sectional study and a systematic review

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dc.audienceComunidad Rosaristaspa
dc.creatorAmaya-Amaya, Jenny-Carolina
dc.creatorSarmiento Monroy, Juan Camilo
dc.creatorCaro-Moreno, Julián
dc.creatorMolano González, Nicolás
dc.creatorMantilla, Rubén D.
dc.creatorRojas-Villarraga, Adriana
dc.creatorAnaya, Juan-Manuel
dc.creator.googleAmaya-Amaya, Jenny
dc.creator.googleSarmiento-Monroy, Juan Camilo
dc.creator.googleCaro-Moreno, Julián
dc.creator.googleMolano-González, Nicolás
dc.creator.googleMantilla, Rubén D.
dc.creator.googleRojas-Villarraga, Adriana
dc.creator.googleAnaya, Juan-Manuel
dc.date.accessioned2014-08-12T19:18:12Z
dc.date.available2014-08-12T19:18:12Z
dc.date.created2013
dc.date.issued2013
dc.description.abstractObjective. This study was performed to determine the prevalence of and associated risk factors for cardiovascular disease (CVD) in Latin American (LA) patients with systemic lupus erythematosus (SLE). Methods. First, a cross-sectional analytical study was conducted in 310 Colombian patients with SLE in whom CVD was assessed. Associated factors were examined by multivariate regression analyses. Second, a systematic review of the literature on CVD in SLE in LA was performed. Results. There were 133 (36.5%) Colombian SLE patients with CVD. Dyslipidemia, smoking, coffee consumption, and pleural effusion were positively associated with CVD. An independent effect of coffee consumption and cigarette on CVD was found regardless of gender and duration of disease. In the systematic review, 60 articles fulfilling the eligibility criteria were included. A wide range of CVD prevalence was found (4%–79.5%). Several studies reported ancestry, genetic factors, and polyautoimmunity as novel risk factors for such a condition.Conclusions. A high rate of CVD is observed in LA patients with SLE. Awareness of the observed risk factors should encourage preventive population strategies for CVD in patients with SLE aimed at facilitating the suppression of cigarette smoking and coffee consumption as well as at the tight control of dyslipidemia and other modifiable risk factors.eng
dc.format.mediumRecurso electrónicospa
dc.format.mimetypeapplication/pdf
dc.format.tipoDocumentospa
dc.identifier.issnISSN:2090-0430
dc.identifier.urihttp://repository.urosario.edu.co/handle/10336/8817
dc.language.isoeng
dc.publisherUniversidad del Rosariospa
dc.relation.citationTitleAutoimmune Diseases
dc.relation.ispartofAutoimmune Diseases, ISSN 2090-04-30, 2013spa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto completo)spa
dc.rights.licenciaEL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma.spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.ddcEnfermedades
dc.subject.decsEnfermedades del corazónspa
dc.subject.decsLupus eritematoso sistémicospa
dc.subject.decsDislipidemiaspa
dc.titleCardiovascular disease in latin american patients with systemic lupus erythematosus: a cross-sectional study and a systematic reviewspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion
dc.type.spaArtículospa
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