Renal involvement at diagnosis of pediatric acute lymphoblastic leukemia

Prada Rico, Mayerly; Rodríguez-Cuellar, Carmen Inés; Arteaga Aya, Lucy Natalia; Nuñez Chates, Claudia Lorena; Garces Sterling, Sandra Patricia; Pierotty, Mathieu; González Chaparro, Luz Esthella; Gastelbondo Amaya, Ricardo

doi:https://doi.org/10.4081/pr.2020.8382

Ítem

Acceso Abierto

Renal involvement at diagnosis of pediatric acute lymphoblastic leukemia

Mostrar el registro sencillo de la publicación

dc.creator	Prada Rico, Mayerly	spa
dc.creator	Rodríguez-Cuellar, Carmen Inés	spa
dc.creator	Arteaga Aya, Lucy Natalia	spa
dc.creator	Nuñez Chates, Claudia Lorena	spa
dc.creator	Garces Sterling, Sandra Patricia	spa
dc.creator	Pierotty, Mathieu	spa
dc.creator	González Chaparro, Luz Esthella	spa
dc.creator	Gastelbondo Amaya, Ricardo	spa
dc.date.accessioned	2020-06-11T13:21:59Z
dc.date.available	2020-06-11T13:21:59Z
dc.date.created	2020-04-08	spa
dc.description.abstract	Acute leukemia is the most common type of cancer in pediatric patients. This type of cancer accounts for a third of all childhood cancer cases. More than half of pediatric acute leukemia patients show signs and symptoms such as hepatomegaly, splenomegaly, pallor, fever and bruising at the time of diagnosis. In early stages of acute lymphoblastic leukemia (ALL), nephromegaly and other renal manifestations such as high blood pressure (HBP) and renal failure are uncommon, although renal infiltration and nephromegaly are common in advanced-stage pediatric patients. This is a retrospective case review with a critical appraisal of the existing evidence from the literature. We present a clinical case of a child with HBP associated with bilateral nephromegaly which resolved after chemotherapy treatment. This patient presented with HBP that required pharmacological treatment, likely owing to nephromegaly. All HBP secondary causes were rejected. Nephromegaly was resolved after chemotherapy treatment, and antihypertensive medication was discontinued. Nephromegaly and HBP are rare manifestations of ALL debut in pediatrics. The present case report illustrates this unusual combination and Suggests clinicians to consider malignancy as its causal factor, especially if the symptoms are accompanied by other suggestive extrarenal manifestations.	eng
dc.format.mimetype	application/pdf
dc.identifier.doi	https://doi.org/10.4081/pr.2020.8382
dc.identifier.issn	2036749X
dc.identifier.issn	20367503
dc.identifier.uri	https://repository.urosario.edu.co/handle/10336/24978
dc.language.iso	eng
dc.publisher	Pediatric Reports	spa
dc.relation.citationIssue	No. 1
dc.relation.citationStartPage	8382
dc.relation.citationTitle	Pediatric Reports
dc.relation.citationVolume	Vol. 12
dc.relation.ispartof	Pediatric Reports, ISSN: 2036749X, 20367503, Vol.12, No.1 (2020-04-08); pp. 8382	spa
dc.relation.uri	https://www.pagepress.org/journals/index.php/pr/article/download/8382/8212	spa
dc.rights.accesRights	info:eu-repo/semantics/openAccess
dc.rights.acceso	Abierto (Texto Completo)	spa
dc.source.instname	instname:Universidad del Rosario	spa
dc.source.reponame	reponame:Repositorio Institucional EdocUR	spa
dc.subject.keyword	Cardiorespiratory Medicine and Haematology	spa
dc.subject.keyword	Medical and Health Sciences	spa
dc.subject.keyword	Oncology and Carcinogenesis	spa
dc.title	Renal involvement at diagnosis of pediatric acute lymphoblastic leukemia	spa
dc.type	article	eng
dc.type.hasVersion	info:eu-repo/semantics/publishedVersion
dc.type.spa	Artículo	spa