Immune protection-inducing protein structures (IMPIPS) against malaria : The weapons needed for beating Odysseus

Patarroyo, Manuel E.; Patarroyo, Manuel A.; Pabón, Laura; Curtidor, Hernando; Poloche, Luis A.

Ítem

Acceso Abierto

Immune protection-inducing protein structures (IMPIPS) against malaria : The weapons needed for beating Odysseus

http://repository.urosario.edu.co/handle/10336/19014

Autores

Patarroyo, Manuel E.

Patarroyo, Manuel A.

Pabón, Laura

Curtidor, Hernando

Poloche, Luis A.

Archivos

PDF

Fecha

2015

Citations

Métricas alternativas

Abstract

The review covers the functional and structural approach followed by our group for more than 34 years in the search for a methodology that allows the rational design of chemically synthesised vaccines. An analogy between Odysseus, the cunning hero of the epic poem Odyssey by Homer, and the elusive Plasmodium parasite has been made, to review our research group's main considerations when developing a rational methodology for designing second generation, modified peptide-based, minimal subunit, multi-antigen, multi-stage, chemically synthesised vaccines against Plasmodium falciparum malaria. © 2015 Elsevier Ltd.

Palabras clave

Impips , Malaria Vaccine , Modified Peptides , Synthetic Peptides

Enlace a la fuente

https://ac.els-cdn.com/S0264410X15014127/1-s2.0-S0264410X15014127-main.pdf?_tid=1b8038aa-cb75-467a-90fb-feb6a865c820&acdnat=1540056249_a7a783bf39eb958684bb1f2d524741d8