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Yellow (577 nm) micropulse laser versus half-dose verteporfin photodynamic therapy in eyes with chronic central serous chorioretinopathy: Results of the Pan-American Collaborative Retina Study (PACORES) Group

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dc.creatorRoca J.A.spa
dc.creatorWu L.spa
dc.creatorFromow-Guerra J.spa
dc.creatorRodríguez F.J.spa
dc.creatorBerrocal M.H.spa
dc.creatorRojas S.spa
dc.creatorLima L.H.spa
dc.creatorGallego-Pinazo R.spa
dc.creatorChhablani J.spa
dc.creatorArevalo J.F.spa
dc.creatorLozano-Rechy D.spa
dc.creatorSerrano M.spa
dc.date.accessioned2020-05-26T00:03:38Z
dc.date.available2020-05-26T00:03:38Z
dc.date.created2018spa
dc.description.abstractPurpose To compare the functional and anatomical outcomes of eyes with chronic central serous chorioretinopathy treated with yellow micropulse (MP) laser versus half-dose verteporfin photodynamic therapy (PDT). Methods This is a multicentre, retrospective comparative study of 92 eyes treated with yellow MP laser (duty cycle of 5%, zero spacing between spots, spot size varied from 100 to 200 ?m, power varied from 320 to 660 mW, and the pulse burst duration was 200 ms) and 67 eyes treated with PDT (half-dose verteporfin (3 mg/m 2) infused over 10 min), followed by laser activation for 83 s. Spot sizes varied from 400 to 2000 ?m. Results In the MP group, at 12 months of follow-up, the mean best corrected visual acuity (BCVA) improved from the logarithm of the minimum angle of resolution (logMAR) of 0.41±0.27 at baseline to 0.21±0.26 (P less than 0.0001), 48.9% (45/92) of eyes had an improvement of ?3 lines of BCVA from baseline, 48.9% (45/92) of eyes remained within 2 lines of baseline BCVA, and only 2.2% (2/92) of eyes lost ?3 lines of BCVA from baseline. In the PDT group, at 12 months of follow-up, the mean BCVA changed from logMAR of 0.50±0.34 at baseline to 0.47±0.34 (P=0.89), 19% (13/67) of eyes had an improvement of ?3 lines of BCVA from baseline, 73% (49/67) of eyes remained within 2 lines of baseline BCVA, and 7% (5/67) of eyes lost ?3 lines of BCVA from baseline. There were no adverse events attributable to the yellow MP laser treatment. One eye in the PDT group developed choroidal neovascularisation, which was treated with three intravitreal bevacizumab injections. Conclusions Both PDT and MP are effective in restoring the macular anatomy. In places where PDT is not available, yellow MP laser may be an adequate treatment alternative. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1136/bjophthalmol-2017-311291
dc.identifier.issn71161
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/23613
dc.language.isoengspa
dc.publisherBMJ Publishing Groupspa
dc.relation.citationEndPage1700
dc.relation.citationIssueNo. 12
dc.relation.citationStartPage1696
dc.relation.citationTitleBritish Journal of Ophthalmology
dc.relation.citationVolumeVol. 102
dc.relation.ispartofBritish Journal of Ophthalmology, ISSN:71161, Vol.102, No.12 (2018); pp. 1696-1700spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85050984803&doi=10.1136%2fbjophthalmol-2017-311291&partnerID=40&md5=f039d52a2a12b538877fe039f4845229spa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordBevacizumabspa
dc.subject.keywordoptical coherenceeng
dc.subject.keywordIndocyanine greenspa
dc.subject.keywordPhotosensitizing agentspa
dc.subject.keywordVerteporfinspa
dc.subject.keywordAdultspa
dc.subject.keywordArticlespa
dc.subject.keywordBest corrected visual acuityspa
dc.subject.keywordCentral serous retinopathyspa
dc.subject.keywordComparative studyspa
dc.subject.keywordControlled studyspa
dc.subject.keywordDisease durationspa
dc.subject.keywordFemalespa
dc.subject.keywordFollow upspa
dc.subject.keywordHumanspa
dc.subject.keywordIntermethod comparisonspa
dc.subject.keywordLaser surgeryspa
dc.subject.keywordMajor clinical studyspa
dc.subject.keywordMalespa
dc.subject.keywordMiddle agedspa
dc.subject.keywordMulticenter study (topic)spa
dc.subject.keywordPhotodynamic therapyspa
dc.subject.keywordPriority journalspa
dc.subject.keywordRetrospective studyspa
dc.subject.keywordSubretinal neovascularizationspa
dc.subject.keywordTreatment outcomespa
dc.subject.keywordYellow micropulse laserspa
dc.subject.keywordCentral serous retinopathyspa
dc.subject.keywordChronic diseasespa
dc.subject.keywordClinical trialspa
dc.subject.keywordFluorescence angiographyspa
dc.subject.keywordLow level laser therapyspa
dc.subject.keywordMulticenter studyspa
dc.subject.keywordOptical coherence tomographyspa
dc.subject.keywordPathophysiologyspa
dc.subject.keywordPhotochemotherapyspa
dc.subject.keywordPhysiologyspa
dc.subject.keywordProceduresspa
dc.subject.keywordVisual acuityspa
dc.subject.keywordAdultspa
dc.subject.keywordCentral serous chorioretinopathyspa
dc.subject.keywordChronic diseasespa
dc.subject.keywordFemalespa
dc.subject.keywordFluorescein angiographyspa
dc.subject.keywordFollow-up studiesspa
dc.subject.keywordHumansspa
dc.subject.keywordIndocyanine greenspa
dc.subject.keywordLaser therapyspa
dc.subject.keywordMalespa
dc.subject.keywordMiddle agedspa
dc.subject.keywordPhotochemotherapyspa
dc.subject.keywordPhotosensitizing agentsspa
dc.subject.keywordRetrospective studiesspa
dc.subject.keywordTomographyeng
dc.subject.keywordTreatment outcomespa
dc.subject.keywordVerteporfinspa
dc.subject.keywordVisual acuityspa
dc.subject.keywordMaculaspa
dc.subject.keywordRetinaspa
dc.subject.keywordTreatment lasersspa
dc.titleYellow (577 nm) micropulse laser versus half-dose verteporfin photodynamic therapy in eyes with chronic central serous chorioretinopathy: Results of the Pan-American Collaborative Retina Study (PACORES) Groupspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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