Ítem
Acceso Abierto

Eventos adversos en el perioperatorio relacionados con el uso de bloqueantes neuromusculares comparado con no utilizarlos durante la anestesia general en adultos : revisión sistemática de la literatura

Mostrar el registro sencillo de la publicación
dc.contributor.advisorManrique Hernández, Rubén Darío
dc.creatorMoscote Rivera, Maria Isabel
dc.creatorPérez Carreño, Juan Guillermo
dc.creatorGutiérrez Pinzón, Vivian Patricia
dc.creator.degreeMagíster en epidemiologíaspa
dc.creator.degreetypeFull timespa
dc.date.accessioned2019-10-25T15:44:04Z
dc.date.available2019-10-25T15:44:04Z
dc.date.created2019-10-18
dc.descriptionIntroducción: Los bloqueadores neuromusculares (BNM) son de uso rutinario en anestesia pese a que no poseen propiedades anestésicas y se han asociado con eventos adversos y mortalidad. Muchas cirugías, incluso abdominales pueden ejecutarse sin BNM. Poco se ha profundizado en el exceso de riesgo de usarlos frente a omitirlos. Indicarlos en situaciones específicas puede disminuir eventos adversos y costo de la anestesia. Objetivo: Estimar la seguridad relativa en el perioperatorio de pacientes adultos sometidos a procedimientos quirúrgicos con anestesia general que han recibido BNM con respecto a aquellos que han recibido otras técnicas anestésicas que no incluyen BNM. Métodos: Revisión Sistemática de la Literatura. Criterios de Selección: Ensayos Clínicos o estudios observacionales en adultos sometidos a cirugías que requieran anestesia general, que reporten eventos adversos en el perioperatorio, con el uso y sin el uso de BNM. Fueron excluidos estudios en niños, pacientes obesos, embarazadas, traumatizados o sometidos a cirugía cardíaca. Búsqueda y Selección de artículos: En los últimos 15 años en PubMed, EMBASE, LILACS, Cochrane y literatura gris, sin exclusión de idiomas, usando términos y sinónimos Decs, Mesh o Emtree, con la estrategia de búsqueda usando términos: “Anaesthesia” (P) + “Neuromuscular Blocking Agent” (I) + “Adverse events” (D), incluyendo todos los sinónimos de interés. Se establecieron límites de fecha de publicación y edad. Se evaluaron ensayos clínicos y estudios observacionales de manera separada para definir la viabilidad de un metanálisis. Se aplicó el flujograma y la lista de chequeo PRISMA (Preferred Items for Systematic Reviews and Metanalisis). Antes de iniciar la búsqueda, el protocolo fue registrado en PROSPERO, con el número CRD42019128550, realizando solo, modificación en la estrategia de búsqueda y notificada a PROSPERO. La búsqueda se realizó el 18 de mayo de 2019. Se excluyeron estudios que no abordaban la pregunta o comparación de interés, así como aquellos que cumplieran criterios de exclusión. La calidad de los estudios fue evaluada usando CONSORT, STROBE, New Castle-Ottawa y la herramienta de riesgo de sesgos de Cochrane. Recolección de datos y análisis: Se utilizó Mendeley como gestor bibliográfico, tres revisores independientemente evaluaron la calidad. Los desacuerdos fueron resueltos por un cuarto revisor. Se utilizó Review Manager 5 para la extracción y análisis de datos. Se midió la frecuencia de eventos adversos, clasificándolos así: complicaciones respiratorias, despertar intraoperatorio y anafilaxia, así como la frecuencia de recurarización residual en los estudios seleccionados. Riesgo relativo y otras medidas fueron calculadas según la información disponible y homogeneidad de estudios. La calidad de la evidencia fue valorada por el sistema GRADE. Resultados: Se encontraron 433 estudios después de remover duplicados. Se seleccionaron 7 estudios, 4 de ellos observacionales con buena concordancia y calidad. Se realizó metanálisis de 4 estudios de cohortes prospectivos, encontrando un riesgo incrementado de complicaciones respiratorias cuando se usan BNM. (RR: 2,71 con IC95% 1,99-3,69). Otros eventos adversos de interés no pudieron ser evaluados. Conclusiones: Hay evidencia de calidad moderada que sugiere que existe un riesgo incrementado de complicaciones respiratorias postoperatorias cuando se usan BNM. Para establecer causalidad, deben realizarse estudios controlados.spa
dc.description.abstractIntroduction: Neuromuscular Blockers Agents (NMBA) are routinely used in anaesthesia, although they don´t have anaesthetic properties and adverse events and mortality have been reported. Muscular relaxation is more a result of quality of anaesthesia that a muscular paralysis. Like this, abdominal surgeries are realized under anaesthesia without NMBA. Efforts made to avoid Postoperative Residual Curarization and intraoperative awareness have not diminished their incidence, and risk of use NMBA is not established. Judicious use of NMBA in specific situations may decrease adverse effects and cost of anaesthesia. Objective: Make a comparison of frequency of adverse events on perioperative period of adult patients, who suffer surgical procedures under general anaesthesia, in whose received NMBA with respect those received other techniques without NMBA. Methods: Systematic Review of literature. Eligibility criteria: Clinical trial if were published, observational studies in adults with surgery that reporting adverse events and mortality during perioperative period with use or without NMBAs. Studies on paediatric or obese patient, trauma, obstetric and cardiac surgery were excluded. Search and select Methods: Last fifteen years in PubMed, EMBASE, LILACS, Cochrane, and grey literature, without exclusion languages, seeking with Decs, Mesh, emtree and synonymous. Search strategy was: "Anaesthesia" (P) + "Neuromuscular Blocking Agents" (I) + “Adverse Effects” (O), including synonymous. We will use PRISMA (Preferred Items for Systematic Reviews and Metanalysis) flow chart and checklist. The protocol was registered on PROSPERO with the number CRD42019128550 and only was modified search strategy before beginning. Collect and analysis: Mendeley will be selected as reference manager. Independently, three reviewers seemed, selected and evaluated quality of articles. In disagreement case, a fourth reviewer decided. PRISMA checklist will be used to design of review, Review Manager 5 to analyse cuantitative data. Frequency of adverse events was measured, incidence of residual neuromuscular blockade, relative risk and others according information available and homogeneity of studies. Checklist CONSORT, STROBE, New Castle-Ottawa and risk of bias tool of Cochrane and GRADE System for certainty of evidence. Results: 433 studies were founded after duplicated to be removed. Seven studies were select, and four of them, observational studies with good agreement, methodological and report quality. Metanalysis of four prospective cohort studies were performed, finding an increased risk of postoperative respiratory complications when using NMBA (RR: 2,71 with IC95% 1,99-3,69). Other adverse events of interest could not be evaluated. Conclusions: There is evidence that suggest an increased risk of postoperative respiratory complications when NMBA were used. To establish causality, controlled trials should be performed. There is not enough information about other adverse events.spa
dc.description.embargo2019-10-25 10:50:01: Script de automatizacion de embargos. No se encontró correo, se envío correo al autor: Cordial saludo respetado autor:Se ha realizado la publicación de su documento " Eventos adversos en el perioperatorio relacionados con el uso de bloqueantes neuromusculares comparado con no utilizarlos durante la anestesia general en adultos : revisión sistemática de la literatura " en el Repositorio Institucional EdocUR de la Universidad del Rosario. Usted escogió la opción "Restringido (Temporalmente bloqueado)", por lo que el documento ha quedado con embargo hasta el 26 de octubre de 2021, en concordancia con las Políticas de Acceso Abierto de la Universidad. Si usted desea dejarlo con acceso abierto antes de finalizar dicho periodo o si por el contrario desea extender el embargo al finalizar este tiempo, puede enviar un correo a esta misma dirección realizando la solicitud. Tenga en cuenta que los documentos en acceso abierto propician una mayor visibilidad de su producción académica y científica. Quedo atento a cualquier inquietud o sugerencia"
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.48713/10336_20488
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/20488
dc.language.isospaspa
dc.publisherUniversidad del Rosariospa
dc.publisher.departmentMaestría en Actividad Física y Saludspa
dc.publisher.otherUniversidad CESspa
dc.publisher.programMaestría en Epidemiologíaspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.rights.licenciaEL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma. PARGRAFO: En caso de presentarse cualquier reclamación o acción por parte de un tercero en cuanto a los derechos de autor sobre la obra en cuestión, EL AUTOR, asumirá toda la responsabilidad, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos la universidad actúa como un tercero de buena fe. EL AUTOR, autoriza a LA UNIVERSIDAD DEL ROSARIO, para que en los términos establecidos en la Ley 23 de 1982, Ley 44 de 1993, Decisión andina 351 de 1993, Decreto 460 de 1995 y demás normas generales sobre la materia, utilice y use la obra objeto de la presente autorización. -------------------------------------- POLITICA DE TRATAMIENTO DE DATOS PERSONALES. Declaro que autorizo previa y de forma informada el tratamiento de mis datos personales por parte de LA UNIVERSIDAD DEL ROSARIO para fines académicos y en aplicación de convenios con terceros o servicios conexos con actividades propias de la academia, con estricto cumplimiento de los principios de ley. Para el correcto ejercicio de mi derecho de habeas data cuento con la cuenta de correo habeasdata@urosario.edu.co, donde previa identificación podré solicitar la consulta, corrección y supresión de mis datos.spa
dc.source.bibliographicCitationBeecher HK, Todd DP. A study of the deaths associated with anesthesia and surgery: based on a study of 599, 548 anesthesias in ten institutions 1948-1952, inclusive. Annals of surgery. 1954;140(1):2-35.spa
dc.source.bibliographicCitationArbous MS, Grobbee DE, van Kleef JW, de Lange JJ, Spoormans H, Touw P, et al. Mortality associated with anaesthesia: a qualatative analysis to identify risk factors. Anaesthesia. 2001;56(February):1141-53.spa
dc.source.bibliographicCitationNaguib M, Magboul MM. Adverse effects of neuromuscular blockers and their antagonists. Middle East journal of anesthesiology. 1998;14(5):341-73.spa
dc.source.bibliographicCitationDonati F. Cost-benefit analysis of neuromuscular blocking agents. Canadian Journal of Anaesthesia. 1994;41(5 II):R3-7.spa
dc.source.bibliographicCitationBrull SJ, Kopman AF. Current Status of Neuromuscular Reversal and Monitoring. Anesthesiology. 2017;126(1):173-90.spa
dc.source.bibliographicCitationBrull SJ, Naguib M, Miller RD. Residual neuromuscular block: Rediscovering the obvious. Anesthesia and Analgesia. 2008;107(1):11-4.spa
dc.source.bibliographicCitationBeny K, Piriou V, Dussart C, Hénaine R, Aulagner G, Armoiry X. Impact du sugammadex sur les consommations de curares: étude pharmaco-épidémiologique multicentrique dans les centres hospitalo-universitaires et hôpitaux d’instructions des armées français. Annales Françaises d’Anesthésie et de Réanimation. 2013;32(12):838-43.spa
dc.source.bibliographicCitationGrosse-Sundrup M, Henneman JP, Sandberg WS, Bateman BT, Uribe JV, Nguyen NT, et al. Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study. Bmj. 2012;345(oct15 5):e6329-e6329.spa
dc.source.bibliographicCitationOrtega A, Sarobe C, Giráldez J, Iribarren MJ. Cost analysis of neuromuscular blocking agents in the operating room: Cisatracurium, atracurium, vecuronium and rocuronium. Pharmacy World and Science. 2000;22(3):82-7.spa
dc.source.bibliographicCitationClaudius C, Garvey LH, Viby-Mogensen J. The undesirable effects of neuromuscular blocking drugs. Anaesthesia. 2009;64(SUPPL. 1):10-21.spa
dc.source.bibliographicCitationKurata J, Hemmings HC. Memory and awareness in anaesthesia. British Journal of Anaesthesia. 2015;115(July):i1-3.spa
dc.source.bibliographicCitationArbous MS, Meursing AEE, van Kleef JW, de Lange JJ, Spoormans HH a JM, Touw P, et al. Impact of anesthesia management characteristics on severe morbidity and mortality. Anesthesiology. 2005;102(2):257-68; quiz 491-2.spa
dc.source.bibliographicCitationKollmann-Camaiora A, Alsina E, Domínguez A, del Blanco B, Yepes MJ, Guerrero JL, et al. Protocolo clínico asistencial de manejo de la hipertermia maligna. Revista Espanola de Anestesiologia y Reanimacion. 2017;64(1):32-40.spa
dc.source.bibliographicCitationGrabitz SD, Rajaratnam N, Changani K, Thevathasan T, Teja BJ, Deng H, et al. The Effects of Postoperative Residual Neuromuscular Blockade on Hospital Costs and Intensive Care Unit Admission. Anesthesia & Analgesia. 2019;128(6):1129-36.spa
dc.source.bibliographicCitationBaete S, Vercruysse G, Laenen MV, De Vooght P, Van Melkebeek J, Dylst D, et al. The effect of deep versus moderate neuromuscular block on surgical conditions and postoperative respiratory function in bariatric laparoscopic surgery: A randomized, double blind clinical trial. Anesthesia and Analgesia. 2017;124(5):1469-75.spa
dc.source.bibliographicCitationBronsert MR, Henderson WG, Monk TG, Richman JS, Nguyen JD, Sum-Ping JT, et al. Intermediate-acting nondepolarizing neuromuscular blocking agents and risk of postoperative 30-day morbidity and mortality, and long-term survival. Anesthesia and Analgesia. 2017;124(5):1476-83.spa
dc.source.bibliographicCitationLagasse RS. Anesthesia safety: model or myth? A review of the published literature and analysis of current original data. Anesthesiology. 2002;97(6):1609-17.spa
dc.source.bibliographicCitationWorld Health Organization I. La cirugía segura salva vidas. 2008; Disponible en: http://apps.who.int/iris/bitstream/handle/10665/70083/WHO_IER_PSP_2008.05_spa.pdf?sequence=1spa
dc.source.bibliographicCitationAlkire BC, Raykar NP, Shrime MG, Weiser TG, Bickler SW, Rose JA, et al. Global access to surgical care: A modelling study. The Lancet Global Health. 2015;3(6):e316-23.spa
dc.source.bibliographicCitationWatters DA, Hollands MJ, Gruen RL, Maoate K, Perndt H, McDougall RJ, et al. Perioperative mortality rate (POMR): A global indicator of access to safe surgery and anaesthesia. World Journal of Surgery. 2015;39(4):856-64.spa
dc.source.bibliographicCitationAhiskalioglu A, Ince I, Ahiskalioglu EO, Oral A, Aksoy M, Yiǧiter M, et al. Is Neuromuscular Blocker Necessary in Pediatric Patients Undergoing Laparoscopic Inguinal Hernia Repair with Percutaneous Internal Ring Suturing? European Journal of Pediatric Surgery. 2017;27(3):263-8.spa
dc.source.bibliographicCitationGueret G, Rossignol B, Kiss G, Wargnier JP, Spielman S, Arvieux CC, et al. Is Muscle Relaxant Necessary for Cardiac Surgery? Anesthesia and Analgesia. 2004;99:1330-3.spa
dc.source.bibliographicCitationAmbrogi MC, Fanucchi O, Korasidis S, Davini F, Gemignani R, Guarracino F, et al. Nonintubated thoracoscopic pulmonary nodule resection under spontaneous breathing anesthesia with laryngeal mask. Innovations (Philadelphia, Pa). 2014;9(4):276-80.spa
dc.source.bibliographicCitationKoo B-W, Jung K-W, Oh A-Y, Kim E-Y, Na H-S, Choi E-S, et al. Is neuromuscular blocker needed in children undergoing inguinal herniorrhaphy? Medicine. 2017;96(26):e7259-e7259.spa
dc.source.bibliographicCitationLundström Lars H, Strande S, Müller Ann M, Wetterslev J. Use versus avoidance of neuromuscular blocking agent for improving conditions during tracheal intubation or direct laryngoscopy in adults and adolescents. Cochrane Database of Systematic Reviews. 2011;Volume|(7).spa
dc.source.bibliographicCitationJain RA, Shetty AN, Oak SP, Wajekar AS, Garasia MB. Effects of avoiding neuromuscular blocking agents during maintenance of anaesthesia on recovery characteristics in patients undergoing craniotomy for supratentorial lesions: A randomised controlled study. Indian Journal of Anaesthesia. 2017;61(1):42-7.spa
dc.source.bibliographicCitationKirmeier E, Eriksson LI, Lewald H, Jonsson Fagerlund M, Hoeft A, Hollmann M, et al. Post-anaesthesia pulmonary complications after use of muscle relaxants (POPULAR): a multicentre, prospective observational study. The Lancet Respiratory Medicine. 2018;2600(18):1-12.spa
dc.source.bibliographicCitationPandit J. NAP5: Accidental awareness during general anesthesia in the United Kingdom and Ireland. 2014;(September).spa
dc.source.bibliographicCitationHarper NJN, Cook TM, Garcez T, Farmer L, Floss K, Marinho S, et al. Anaesthesia, surgery, and life-threatening allergic reactions: epidemiology and clinical features of perioperative anaphylaxis in the 6th National Audit Project (NAP6). British Journal of Anaesthesia. 2018;121(1):159-71.spa
dc.source.bibliographicCitationSmith CR, Lisa MPH, Simon P, Ma F, Wu J. Canadian physicians ’ knowledge and counseling practices related to antibiotic use and antimicrobial resistance. Canadian Family Physician. 2017;63:e526-35.spa
dc.source.bibliographicCitationSaito S, Mukohara K, Miyata Y. Chronological Changes in Japanese Physicians’ Attitude and Behavior Concerning Relationships with Pharmaceutical Representatives : A Qualitative Study. Plos one. 2014;9(9):1-7.spa
dc.source.bibliographicCitationMurphy GS, Szokol JW, Marymont JH, Greenberg SB, Avram MJ, Vender JS. Residual neuromuscular blockade and critical respiratory events in the postanesthesia care unit. Anesthesia and Analgesia. 2008;107(1):130-7.spa
dc.source.bibliographicCitationDebaene B, Plaud B, Dilly M, Donati F, Ph D. Residual Paralysis in the PACU after a Single Intubating Dose of Nondepolarizing Muscle Relaxant with an intermediate duration of action. Anestehesiology. 2003;98(5):1042-8.spa
dc.source.bibliographicCitationGriffith H, Johnson G. The use of curare in General Anesthesia. Canadian Journal of Anaesthesia. 1942;3:418-20.spa
dc.source.bibliographicCitationThesleff S. The pharmacological properties of succinylcholine iodide; with particular reference to its clinical use as a muscular relaxant. Acta Physiol Scand. 10 de septiembre de 1952;26(2-3):103-29.spa
dc.source.bibliographicCitationPerry JJ, Lee JS, Sillberg VAH, Wells GA. Rocuronium versus succinylcholine for rapid sequence induction intubation. Cochrane Database Syst Rev. 2008;(2):CD002788.spa
dc.source.bibliographicCitationTran DTT, Newton Ethan K, Mount Victoria AH, Lee Jacques S, Wells George A, Perry Jeffrey J. Rocuronium versus succinylcholine for rapid sequence induction intubation. Cochrane Database of Systematic Reviews. 2015;(10).spa
dc.source.bibliographicCitationAli HH, Savarese JJ, Embree PB, Basta SJ, Stout RG, Bottros LH, et al. Clinical pharmacology of mivacurium chloride (BW B1090U) infusion: comparison with vecuronium and atracurium. Br J Anaesth. 1988;61(5):541-6.spa
dc.source.bibliographicCitationSiddik-Sayyid SM, Taha SK, Kanazi GE, Chehade J-MA, Zbeidy RA, Al Alami AA, et al. Excellent intubating conditions with remifentanil-propofol and either low-dose rocuronium or succinylcholine. Can J Anaesth. 2009;56(7):483-8.spa
dc.source.bibliographicCitationHerbstritt A, Amarakone K. Towards evidence-based emergency medicine: best BETs from the Manchester Royal Infirmary. BET 3: is rocuronium as effective as succinylcholine at facilitating laryngoscopy during rapid sequence intubation? Emerg Med J. 2012;29(3):256-8.spa
dc.source.bibliographicCitationChavan SG, Gangadharan S, Gopakumar AK. Comparison of rocuronium at two different doses and succinylcholine for endotracheal intubation in adult patients for elective surgeries. Saudi J Anaesth. 2016;10(4):379-83.spa
dc.source.bibliographicCitationWierda JM, van den Broek L, Proost JH, Verbaan BW, Hennis PJ. Time course of action and endotracheal intubating conditions of Org 9487, a new short-acting steroidal muscle relaxant; a comparison with succinylcholine. Anesth Analg. 1993;77(3):579-84.spa
dc.source.bibliographicCitationLaszlo G, Chingmuh L, Young-Moon C, Nguyen NT, Tsai SK. Neuromuscular Pharmacology of TAAC3, a New Nondepolarizing Muscle Relaxant with Rapid Onset and Ultrashort Duration of Action. Anesthesia & Analgesia. 2002;94:879-85.spa
dc.source.bibliographicCitationGoswami LN, Olds TJ, Monk TG, Quinn L, Dilger JP, Shanawaz MA, et al. Isomeric Carborane Neuromuscular Blocking Agents. ChedMedChem Chemistry enabling drug discovery. 2019;1-9-.spa
dc.source.bibliographicCitationBasta, S J, Savarese, J J, Ali, Hassan H, Embree, P B. Clinical Pharmacology of Doxacurium Chloride: A New Long-actin Nondepolarizing Muscle Relaxant. Anesthesiology. 1988;69:478-86.spa
dc.source.bibliographicCitationMiguel R, witkowsky T, Hideo N, Fragen R, Bartkowsky R, Foldes F. Evaluation of Neuromuscular and Cardiovascular Effects of Two Doses of Rapacuronium ( ORG 9487 ) versus Mivacurium and Succinylcholine. Anesthesiology. 1999;91:1648-54.spa
dc.source.bibliographicCitationGray C. A Reassesment of the Signs and Levels of Anaesthesia. Irish journal of medical science. 1960;Nov(419):499-508.spa
dc.source.bibliographicCitationNaguib M, Lien CA, Meistelman C. Pharmacology of neuromuscular blocking drugs. En: Miller´s Anesthesia. Eight edition. Elsevier Inc.; 2015. p. 958-94.spa
dc.source.bibliographicCitationHobbiger F. The mechanism of anticurare action of certain neostigmine analogues. British journal of pharmacology and chemotherapy. 1952;7(2):223-36.spa
dc.source.bibliographicCitationBom A, Bradley M, Cameron K, Clark JK, Van Egmond J, Feilden H, et al. A novel concept of reversing neuromuscular block: chemical encapsulation of rocuronium bromide by a cyclodextrin-based synthetic host. Angew Chem Int Ed Engl. 2002;41(2):266-70spa
dc.source.bibliographicCitationHerring WJ, Woo T, Assaid CA, Lupinacci RJ, Lemmens HJ, Blobner M, et al. Sugammadex efficacy for reversal of rocuronium- and vecuronium-induced neuromuscular blockade: A pooled analysis of 26 studies. Journal of Clinical Anesthesia. 2017;41:84-91.spa
dc.source.bibliographicCitationDella Rocca G, Di Marco P, Beretta L. Do we need to use sugammadex at the end of general anesthesia to reverse the action of neuromuscular blocking agents? Position Paper on sugammadex use. Minerva Anestesiológica. 2013;79(6):661-6.spa
dc.source.bibliographicCitationde Boer HD. Neuromuscular transmission: New concepts and agents. Journal of Critical Care. 2009;24(1):36-42.spa
dc.source.bibliographicCitationHager HH, Burns B. Succinylcholine Chloride. En: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019. Disponible en: http://www.ncbi.nlm.nih.gov/books/NBK499984/spa
dc.source.bibliographicCitationMiller RD, Cohen NH, Eriksson LI, Fleisher LA. Miller´s Anesthesia. Eighth edi. Miller RD, editor. Philadephia, PA: Elsevier Inc.; 2015.spa
dc.source.bibliographicCitationAndersson ML, Møller AM, Wildgaard K. Butyrylcholinesterase deficiency and its clinical importance in anaesthesia: a systematic review. Anaesthesia. 2019;74(4):518-28.spa
dc.source.bibliographicCitationWichmann S, Færk G, Bundgaard JR, Gätke MR. Patients with prolonged effect of succinylcholine or mivacurium had novel mutations in the butyrylcholinesterase gene. Pharmacogenetics and Genomics. 2016;26(7):351-6.spa
dc.source.bibliographicCitationDa Silva AS, Pimentel VC, Fiorenza AM, França RT, Tonin AA, Jaques JA, et al. Activity of cholinesterases and adenosine deaminase in blood and serum of rats experimentally infected with Trypanosoma cruzi. Annals of Tropical Medicine & Parasitology. 2011;105(5):385-91.spa
dc.source.bibliographicCitationGanigara A, Ravishankar C, Ramavakoda C, Nishtala M. Fatal hyperkalemia following succinylcholine administration in a child on oral propranolol. Drug Metabolism and Personalized Therapy. 2015;30(1):69-71.spa
dc.source.bibliographicCitationMartyn JAJ, Richtsfeld M. Succinylcholine-induced Hyperkalemia in Acquired Pathologic States. Anesthesiology. 2006;104(1):158-69.spa
dc.source.bibliographicCitationTran DTT, Newton EK, Mount V a. H, Lee JS, Mansour C, Wells GA, et al. Rocuronium vs. succinylcholine for rapid sequence intubation: a Cochrane systematic review. Anaesthesia. junio de 2017;72(6):765-77.spa
dc.source.bibliographicCitationShoenberger JM, Mallon WK. Rocuronium Versus Succinylcholine Revisited: Succinylcholine Remains the Best Choice. Annals of Emergency Medicine. 2018;71(3):398-9.spa
dc.source.bibliographicCitationSzakmany T, Woodhouse T. Use of cisatracurium in critical care a review of the literature. Minerva Anestesiologica. 2015;81(4):450-60.spa
dc.source.bibliographicCitationLu Z, Rosenberg H, Li G. Prevalence of malignant hyperthermia diagnosis in hospital discharge records in California, Florida, New York, and Wisconsin. Journal of Clinical Anesthesia. 2017;39:10-4.spa
dc.source.bibliographicCitationSebel PS, Bowdle TA, Ghoneim MM, Rampil IJ, Padilla RE, Gan TJ, et al. The incidence of awareness during anesthesia: A multicenter United States study. Anesthesia and Analgesia. 2004;99(3):833-9.spa
dc.source.bibliographicCitationAytac I, Postaci A, Aytac B, Sacan O, Alay GH, Celik B, et al. Survey of postoperative residual curarization, acute respiratory events and approach of anesthesiologists. Brazilian journal of anesthesiology (Elsevier). 2016;66(1):55-62.spa
dc.source.bibliographicCitationNunes RR, Porto VC, Miranda VT, De Andrade NQ, Carneiro LMM. Risk Factor for Intraoperative Awareness. Revista Brasileira de Anestesiologia. 2012;62(3):365-74.spa
dc.source.bibliographicCitationSandin RH, Enlund G, Samuelsson P, Lennmarken C. Awareness during anaesthesia: a prospective case study. Lancet. 2000;355:707-11.spa
dc.source.bibliographicCitationFernandez A, Frendl G, Sprung J, Kor D, Subramaniam B, Martinez R, et al. Postoperative Pulmonary Complications, Early Mortality, and Hospital Stay Following Noncardiothoracic Surgery: A Multicenter Study by the Perioperative Research Network Investigators. JAMA. 2018;152(2):157-66.spa
dc.source.bibliographicCitationMiskovic A, Lumb AB. Postoperative pulmonary complications. British journal of anaesthesia. 2017;118(3):317–334.spa
dc.source.bibliographicCitationToledo C, Nácul FE, Knibel MF, Silva NB, Rezende E, Grion CMC, et al. Pulmonary complications after non-cardiac surgeries: temporal patterns and risk factors. Anestezjologia Intensywna Terapia. 2014;49(4):245-51.spa
dc.source.bibliographicCitationBelcher AW, Leung S, Cohen B, Yang D, Mascha EJ, Turan A, et al. Incidence of complications in the post-anesthesia care unit and associated healthcare utilization in patients undergoing non-cardiac surgery requiring neuromuscular blockade 2005 – 2013 : A single center study. Journal of Clinical Anesthesia. 2017;43:33-8.spa
dc.source.bibliographicCitationLukannek C, Shae S, Platzbecker K, Raub D, Santer P, Nabel S, et al. The development and validation of the Score for the Prediction of Postoperative Respiratory Complications ( SPORC-2 ) to predict the requirement for early post- operative tracheal re-intubation : a hospital registry study. Anaesthesia. 2019;1-10.spa
dc.source.bibliographicCitationErrando-Oyonarte CL, Moreno-Sanz C, Vila-Caral P, Ruiz de Adana-Belbel JC, Vázquez-Alonso E, Ramírez-Rodríguez JM, et al. Recomendaciones sobre el uso de bloqueo neuromuscular profundo por parte de anestesiólogos y cirujanos. Consenso AQUILES (Anestesia QUIrúrgica para Lograr Eficiencia y Seguridad). Revista Espanola de Anestesiologia y Reanimacion. 2017;64(2):95-104.spa
dc.source.bibliographicCitationXará D, Santos A, Abelha F. Acontecimientos adversos respiratorios en la unidad de cuidados postanestésicos. Archivos de Bronconeumologia. 2015;51(2):69-75.spa
dc.source.bibliographicCitationLedowski T, Hillyard S, O’Dea B, Archer R, Vilas FB, Kyle B. Introduction of sugammadex as standard reversal agent: Impact on the incidence of residual neuromuscular blockade and postoperative patient outcome. Indian Journal of Anaesthesia. 2013;57(1):46-51.spa
dc.source.bibliographicCitationSchreiber J. Management of neuromuscular blockade in ambulatory patients. Current Opinion in Anaesthesiology. 2014;27(6):583-8.spa
dc.source.bibliographicCitationYamamoto T, Schindler E. Where and how do anaesthetics act? Mechanisms of action in the central nervous system. Anestezjologia Intensywna Terapia. 2014;49(4):288-93.spa
dc.source.bibliographicCitationZbinden AM, Petersen-Felix S, Thomson DA, Maggiorini M, Petersen-Felix S, Lauber R, et al. Anesthetic depth defined using multiple noxious stimuli during isoflurane/oxygen anesthesia: I. Motor reactions. Anesthesiology. 1994;80(May 2014):253-60.spa
dc.source.bibliographicCitationUhrig L, Dehaene S, Jarraya B. Cerebral mechanisms of general anesthesia. Annales francaises d’anesthesie et de reanimation. 2014;33(2):72-82.spa
dc.source.bibliographicCitationAlkire MT, Hudetz AG, Tononi G. Consciusness and Anesthesia. Science. 2008;7(322):876-80.spa
dc.source.bibliographicCitationOsterman JE, Hopper J, Heran WJ, Keane TM, van der Kolk BA. Awareness under anesthesia and the development of posttraumatic stress disorder. General Hospital Psychiatry. 2001;23(4):198-204.spa
dc.source.bibliographicCitationZhu J, Zhang X-R, Yang H. Effects of combined epidural and general anesthesia on intraoperative hemodynamic responses, postoperative cellular immunity, and prognosis in patients with gallbladder cancer. Medicine. 2017;96(10):e6137-e6137.spa
dc.source.bibliographicCitationBardia A, Sood A, Mahmood F, Orhurhu V, Mueller A, Montealegre-gallegos M. Combined Epidural-General Anesthesia vs General Anesthesia Alone for Elective Abdominal Aortic Aneurysm Repair. JAMA. 2016;151(12):1116-23.spa
dc.source.bibliographicCitationHemmerling T, Donati F. Neuromuscular blockade at the larynx , the diaphragm and the corrugator supercilii muscle : a review. Canadian Journal of Anesthesia. 2003;50(8):779-94.spa
dc.source.bibliographicCitationSato N, Hagiwara Y, Watase H, Hasegawa K. A comparison of emergency airway management between neuromuscular blockades alone and rapid sequence intubation : an analysis of multicenter prospective study. BMC Research Notes. 2017;(January).spa
dc.source.bibliographicCitationBourenne J, Hraiech S, Roch A, Gainnier M, Papazian L, Forel J-M. Sedation and neuromuscular blocking agents in acute respiratory distress syndrome. Annals of Translational Medicine. 2017;5(14):291-291.spa
dc.source.bibliographicCitationMoher D, Liberati A, Tetzlaff J, Altman DG, Altman D, Antes G, et al. Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. PLoS Medicine. 2009;6(7).spa
dc.source.bibliographicCitationSchulz KF, Altman DG, Moher D, Group C. & reporting CONSORT 2010 Statement : updated guidelines for reporting parallel group randomised trials. British medical journal. 2010;340(march).spa
dc.source.bibliographicCitationVon Elm E, Altman DG, Pocock S, Gotzsche PC, Vandenbroucke JP. Strengthening the reporting of observational studies in epidemiology ( STROBE ) statement : guidelines for reporting observational studies. Brithish Medical Journal. octubre de 2007;335(7624):806 – 808.spa
dc.source.bibliographicCitationStang A. Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. European Journal of Epidemology. 2010;25:603-5.spa
dc.source.bibliographicCitationBlobner M, Hunter JM, Ulm K, Hollmann M. Neuromuscular monitoring and reversal: responses to the POPULAR study. The Lancet Respiratory Medicine. 2019;7:e7-8.spa
dc.source.bibliographicCitationKhuri SF, Henderson WG, Depalma RG. Determinants of Long-Term Survival After Major Surgery and the Adverse Effect of Postoperative Complications. Annals of Surgery. 2005;242(3):326-43.spa
dc.source.bibliographicCitationRostin P, Teja BJ, Friedrich S, Shae S, Murugappan KR, Ramachandran SK, et al. The association of early postoperative desaturation in the operating theatre with hospital discharge to a skilled nursing or long-term care facility *. Anaesthesia. 2019;(April 2018):1-11.spa
dc.source.bibliographicCitationManterola C, Asenjo-lobos C, Otzen T. Jerarquización de la evidencia. Niveles de evidencia y grados de recomendación de uso actual. Revista Chilena de Infectología. 2014;31(6):705-18.spa
dc.source.bibliographicCitationJammer I, Wickboldt N, Sander M, Smith A, Schultz MJ, Pelosi P, et al. Standards for definitions and use of outcome measures for clinical effectiveness research in perioperative medicine : European Perioperative Clinical Outcome ( EPCO ) definitions A statement from the ESA-ESICM joint taskforce on perioperative outcome meas. European Journal of Anaesthesiology. 2015;32:88-105.spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subjectAnestesia generalspa
dc.subjectComplicaciones postoperatoriasspa
dc.subjectDespertar intraoperatoriospa
dc.subjectAnafilaxiaspa
dc.subjectSeguridad del pacientespa
dc.subject.ddcCiencias médicas, Medicinaspa
dc.subject.keywordGeneral anaesthesiaspa
dc.subject.keywordAnaphylaxisspa
dc.subject.keywordAdverse effectsspa
dc.subject.keywordPatient safetyspa
dc.subject.keywordPostoperative complicationsspa
dc.subject.keywordIntraoperative awarenessspa
dc.subject.lembMedicinaspa
dc.subject.lembEpidemiologíaspa
dc.titleEventos adversos en el perioperatorio relacionados con el uso de bloqueantes neuromusculares comparado con no utilizarlos durante la anestesia general en adultos : revisión sistemática de la literaturaspa
dc.typemasterThesiseng
dc.type.documentTrabajo de gradospa
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion
dc.type.spaTesis de maestríaspa
local.department.reportEscuela de Medicina y Ciencias de la Saludspa
Archivos
Bloque original
Mostrando1 - 1 de 1
Miniatura
Nombre:
Trabajo de Grado Final 21 oct 2019.pdf
Tamaño:
1.81 MB
Formato:
Adobe Portable Document Format
Descripción:
Trabajo de Grado
Descargar
Colecciones
Maestría en Epidemiología