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Myeloid-derived-supressor cells as regulators of th eimmune system

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dc.creatorGabilovich, Dmitryspa
dc.creatorNagaraj, Srinivasspa
dc.date.accessioned2020-08-19T14:39:55Z
dc.date.available2020-08-19T14:39:55Z
dc.date.created2009-03spa
dc.description.abstractMyeloid-derived suppressor cells (MDSCs) are a heterogeneous population of cells that expand during cancer, inflammation and infection, and that have a remarkable ability to suppress T-cell responses. These cells constitute a unique component of the immune system that regulates immune responses in healthy individuals and in the context of various diseases. In this Review, we discuss the origin, mechanisms of expansion and suppressive functions of MDSCs, as well as the potential to target these cells for therapeutic benefit.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1038/nri2506
dc.identifier.issnISSN: 1474-1733
dc.identifier.issnEISSN: 1474-1741
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/26624
dc.language.isoengspa
dc.publisherNature reviews Immunologyspa
dc.relation.citationEndPage174
dc.relation.citationStartPage162
dc.relation.citationTitleNature Reviews Immunology
dc.relation.citationVolumeVol. 9
dc.relation.ispartofNature Reviews Immunology, ISSN: 1474-1733 ; EISSN: 1474-1741, Vol.9 (2009);pp. 162–174spa
dc.relation.urihttps://www.nature.com/articles/nri2506#Abs3spa
dc.rights.accesRightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.accesoRestringido (Acceso a grupos específicos)spa
dc.sourceNature Reviews Immunologyspa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.keywordImmunosuppressispa
dc.subject.keywordSuppressionspa
dc.titleMyeloid-derived-supressor cells as regulators of th eimmune systemspa
dc.title.TranslatedTitleCélulas supresoras derivadas de mieloides como reguladoras del sistema inmunológicospa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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