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Characterisation of the Plasmodium vivax Pv38 antigen

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dc.creatorMongui, Alvarospa
dc.creatorAngel, Diana I.spa
dc.creatorGuzman, Catalinaspa
dc.creatorVanegas, Magnoliaspa
dc.creatorPatarroyo, Manuel A.spa
dc.date.accessioned2020-05-26T00:02:33Z
dc.date.available2020-05-26T00:02:33Z
dc.date.created2008spa
dc.description.abstractThis study describes the identification and characterisation of Pv38, based on the available genomic sequence of Plasmodium vivax and previous studies done with its Plasmodium falciparum homologue: Pf38. Pv38 is a 355 amino acid long peptide encoded by a single exon gene, for which orthologous genes have been identified in other Plasmodium species by bioinformatic approaches. As for Pf38, Pv38 was found to contain a s48/45 domain which is usually found in proteins displayed on gametocytes surface. The association of Pv38 with detergent-resistant membranes (DRMs), its expression in mature blood stages of the parasite (mainly schizonts) and the detection of its recombinant protein by sera from Aotus monkeys previously exposed to the parasite, were here assessed to further characterise this new antigen. © 2008 Elsevier Inc. All rights reserved.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.bbrc.2008.08.163
dc.identifier.issn0006291X
dc.identifier.issn10902104
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/23500
dc.language.isoengspa
dc.relation.citationEndPage330
dc.relation.citationIssueNo. 2
dc.relation.citationStartPage326
dc.relation.citationTitleBiochemical and Biophysical Research Communications
dc.relation.citationVolumeVol. 376
dc.relation.ispartofBiochemical and Biophysical Research Communications, ISSN:0006291X, 10902104, Vol.376, No.2 (2008); pp. 326-330spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-52949134094&doi=10.1016%2fj.bbrc.2008.08.163&partnerID=40&md5=5acc753c336cf90af4392920dd84cfe6spa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordAntigen pv38spa
dc.subject.keywordParasite antigenspa
dc.subject.keywordRecombinant proteinspa
dc.subject.keywordUnclassified drugspa
dc.subject.keywordAmino acid sequencespa
dc.subject.keywordAntigen detectionspa
dc.subject.keywordAotusspa
dc.subject.keywordArticlespa
dc.subject.keywordNonhumanspa
dc.subject.keywordNucleotide sequencespa
dc.subject.keywordOpen reading framespa
dc.subject.keywordParasite virulencespa
dc.subject.keywordPlasmodium vivaxspa
dc.subject.keywordPriority journalspa
dc.subject.keywordProtein expressionspa
dc.subject.keywordProtein isolationspa
dc.subject.keywordSerumspa
dc.subject.keywordAmino acid sequencespa
dc.subject.keywordAnimalsspa
dc.subject.keywordAntigenseng
dc.subject.keywordGeneseng
dc.subject.keywordMolecular sequence dataspa
dc.subject.keywordPlasmodium vivaxspa
dc.subject.keywordRecombinant proteinsspa
dc.subject.keywordTranscriptioneng
dc.subject.keywordPlasmodium falciparumspa
dc.subject.keywordPlasmodium vivaxspa
dc.subject.keywordDrmsspa
dc.subject.keywordMalariaspa
dc.subject.keywordPlasmodium vivaxspa
dc.subject.keywordPv38spa
dc.subject.keywordVaccine candidatespa
dc.titleCharacterisation of the Plasmodium vivax Pv38 antigenspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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