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Autoimmune diseases in the intensive care unit. An update

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dc.creatorQuintero, Olga L.spa
dc.creatorRojas-Villarraga, Adrianaspa
dc.creatorMantilla, Ruben D.spa
dc.creatorAnaya, Juan-Manuelspa
dc.date.accessioned2020-05-26T00:00:15Z
dc.date.available2020-05-26T00:00:15Z
dc.date.created2013spa
dc.description.abstractAutoimmune diseases (ADs) are a challenge at the intensive care unit. The management of patients with these diseases in the critical care setting has improved over time since there are new and more aggressive alternatives to treat and diagnose them. We aimed to review the current causes of admission, clinical features, outcomes and variables associated with mortality of patients with ADs admitted to the intensive care unit (ICU). International classification criteria for ADs were used to include patients. Search was done through PubMed, SCOPUS, SciELO, and LILACS databases up to December of 2011.Twenty-nine case series and forty-one case reports were analyzed after quality assessment. Respiratory involvement was the leading cause of admission. Systemic lupus erythematosus (SLE) (33.5% of reported patients), rheumatoid arthritis (25%) and systemic vasculitis (15%) were the most frequent ADs in patients admitted to the ICU in the last decade. Mortality ranged from 17% to 55% in case series including all ADs, but in the ones that only included patients with a specific AD, such as SLE, it reached up to 79%. High APACHE score, multi-organ dysfunction, older age and cytopenia were the most reported variables associated with mortality. In conclusion, ADs should always be considered in patients with life threatening conditions that warrant critical care. Variables influencing mortality should be promptly identified in order to improve the patients' outcomes. © 2012 Elsevier B.V.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.autrev.2012.06.002
dc.identifier.issn15689972
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/23188
dc.language.isoengspa
dc.relation.citationEndPage395
dc.relation.citationIssueNo. 3
dc.relation.citationStartPage380
dc.relation.citationTitleAutoimmunity Reviews
dc.relation.citationVolumeVol. 12
dc.relation.ispartofAutoimmunity Reviews, ISSN:15689972, Vol.12, No.3 (2013); pp. 380-395spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84872420680&doi=10.1016%2fj.autrev.2012.06.002&partnerID=40&md5=4e838a6cc49734a779dd6f2c35006dcdspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordAgespa
dc.subject.keywordApachespa
dc.subject.keywordAutoimmune diseasespa
dc.subject.keywordClinical featurespa
dc.subject.keywordCytopeniaspa
dc.subject.keywordHospital admissionspa
dc.subject.keywordHumanspa
dc.subject.keywordIntensive carespa
dc.subject.keywordIntensive care unitspa
dc.subject.keywordMedlinespa
dc.subject.keywordMortalityspa
dc.subject.keywordMultiple organ failurespa
dc.subject.keywordOutcome assessmentspa
dc.subject.keywordReviewspa
dc.subject.keywordRheumatoid arthritisspa
dc.subject.keywordScoring systemspa
dc.subject.keywordSystematic reviewspa
dc.subject.keywordSystemic lupus erythematosusspa
dc.subject.keywordSystemic vasculitisspa
dc.subject.keywordTreatment planningspa
dc.subject.keywordAutoimmune diseasesspa
dc.subject.keywordHumansspa
dc.subject.keywordIntensive care unitsspa
dc.subject.keywordAutoimmune diseasesspa
dc.subject.keywordIntensive care unitspa
dc.subject.keywordIntravenous immunoglobulinsspa
dc.subject.keywordMortalityspa
dc.subject.keywordOutcomespa
dc.subject.keywordTherapeutic plasma exchangespa
dc.titleAutoimmune diseases in the intensive care unit. An updatespa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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