Ítem
Solo Metadatos

Pharmacological venous thromboembolism prophylaxis in radical prostatectomy

Mostrar el registro sencillo de la publicación
dc.creatorValverde-Martinez, Sebastianspa
dc.creatorGonzalez-Rayo, Laura-Andreaspa
dc.creatorPadilla-Fernandez, Barbaraspa
dc.creatorPereira-Bruno, Jorgespa
dc.creatorCoelho, Hugospa
dc.creatorMontesino-Semper, Manuelspa
dc.creatorMüller-Arteaga, Carlosspa
dc.creatorAlvarez-Ossorio-Fernandez, Jose-Luisspa
dc.creatorMigliorini, Filippospa
dc.creatorGarcia-Cenador, Maria-Begoñaspa
dc.creatorLorenzo-Gomez, Maria-Fernandaspa
dc.date.accessioned2020-05-25T23:56:58Z
dc.date.available2020-05-25T23:56:58Z
dc.date.created2020spa
dc.description.abstractBackground and aim: Pulmonary thromboembolism is one of the most common causes of non-surgical death in patients following urological abdominopelvic surgery. Since the beginning of prophylaxis for venous thromboembolic disease, episodes of deep vein thrombosis and pulmonary thromboembolism have decreased. Our objective is to analyse the prognosis factors of thromboembolic disease, the clinical variability in the use of pharmacological prophylaxis and the results of its application. Material and methods: Retrospective multicentric study of 610 patients undergoing radical prostatectomy between December 2013 and November 2014, in 7 general hospitals in Spain, Italy and Portugal. Patients were classified according to their baseline characteristics into thrombotic risk groups and haemorrhagic risk groups. The venous thromboembolic events that occurred in the different groups were analysed. Results: The average age was 65.22 years (48-78). The average body mass index was 26.7 and the average ASA risk 2.1. In all patients, early mobilization began in the first 24 hours. In 4.1% intermittent pneumatic compression was used and 84.6% received pharmacological prophylaxis with low molecular weight heparins. Only 3.4% used the combination of mechanical prophylaxis with pharmacological prophylaxis. We observed a decrease in the incidence of thromboembolic events in the patients who received pharmacological prophylaxis, with an absolute risk reduction of 6.8%. There was no increase in the risk of haemorrhage in the patients who received pharmacological prophylaxis. Conclusions: In this study on patients undergoing radical prostatectomy, there was no difference in haemorrhagic complications derived from the use of pharmacological prophylaxis for venous thromboembolic disease. Pharmacological prophylaxis reduces the risk of presenting a thromboembolic event in patients undergoing radical prostatectomy, although this risk is not associated with the approach technique. © 2019 Elsevier España, S.L.U.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.medcli.2019.04.023
dc.identifier.issn257753
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/22574
dc.language.isoengspa
dc.publisherEdiciones Doyma, S.L.spa
dc.relation.citationEndPage118
dc.relation.citationIssueNo. 4
dc.relation.citationStartPage113
dc.relation.citationTitleMedicina Clinica
dc.relation.citationVolumeVol. 154
dc.relation.ispartofMedicina Clinica, ISSN:257753, Vol.154, No.4 (2020); pp. 113-118spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85068042947&doi=10.1016%2fj.medcli.2019.04.023&partnerID=40&md5=36c40c90b27ae4d8f0ea9c1e50df23a2spa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordAnticoagulant agentspa
dc.subject.keywordLow molecular weight heparinspa
dc.subject.keywordAdultspa
dc.subject.keywordAgedspa
dc.subject.keywordArticlespa
dc.subject.keywordBleedingspa
dc.subject.keywordBody massspa
dc.subject.keywordControlled studyspa
dc.subject.keywordDeep vein thrombosisspa
dc.subject.keywordDevice therapyspa
dc.subject.keywordDisease risk assessmentspa
dc.subject.keywordHumanspa
dc.subject.keywordIncidencespa
dc.subject.keywordLung embolismspa
dc.subject.keywordMajor clinical studyspa
dc.subject.keywordMobilizationspa
dc.subject.keywordPostoperative complicationspa
dc.subject.keywordPostoperative hemorrhagespa
dc.subject.keywordPrognosisspa
dc.subject.keywordProstatectomyspa
dc.subject.keywordRetrospective studyspa
dc.subject.keywordRisk reductionspa
dc.subject.keywordSurgical riskspa
dc.subject.keywordThrombosis preventionspa
dc.subject.keywordVenous thromboembolismspa
dc.subject.keywordClinical variabilityspa
dc.subject.keywordRadical prostatectomyspa
dc.subject.keywordThromboembolic prophylaxisspa
dc.titlePharmacological venous thromboembolism prophylaxis in radical prostatectomyspa
dc.title.TranslatedTitleProfilaxis farmacológica de la tromboembolia venosa en la prostatectomía radicalspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
Archivos
Colecciones
Artículos