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Disease of the Year 2019: Ocular Toxoplasmosis in HIV-infected Patients

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dc.creatorde-la-Torre, Alejandraspa
dc.creatorGómez-Marín, Jorgespa
dc.date.accessioned2020-05-25T23:57:38Z
dc.date.available2020-05-25T23:57:38Z
dc.date.created2020spa
dc.description.abstractOcular toxoplasmosis (OT) may be an initial manifestation of acquired immunodeficiency syndrome (AIDS) in human immunodeficiency virus (HIV)-infected patients. OT has different clinical manifestations and can mimic other intraocular infections. Clinical findings may show single or multifocal retinochoroidal lesions or panuveitis. Atypical presentations are associated with extensive uni- or bilateral areas of retinal necrosis. OT lesions not associated with preexisting retinochoroidal scars are usually due to acquired rather than congenital infection. When CD4+ T cell counts are less than 100 c/uL, vitritis is frequently mild. Isolated anterior uveitis has been reported in single cases. Positive immunoglobulin M (IgM) antibodies are rare but their presence can support the diagnosis. As atypical presentations of OT are common, anterior chamber puncture for multiplex polymerase chain reaction amplification of infectious DNA should be considered, as early diagnosis and treatment can prevent massive tissue destruction and preserve vision. This review provides an overview of OT in HIV–infected patients. © 2020, © 2020 Taylor and Francis Group, LLC.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1080/09273948.2020.1735450
dc.identifier.issn9273948
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/22712
dc.language.isoengspa
dc.publisherTaylor and Francis Ltdspa
dc.relation.citationTitleOcular Immunology and Inflammation
dc.relation.ispartofOcular Immunology and Inflammation, ISSN:9273948,(2020)spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85081749258&doi=10.1080%2f09273948.2020.1735450&partnerID=40&md5=608468b2757899bf2f18a53955f23ff9spa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordDiagnosisspa
dc.subject.keywordHivspa
dc.subject.keywordOcular toxoplasmosisspa
dc.subject.keywordRetinochoroiditisspa
dc.subject.keywordToxoplasma gondiispa
dc.subject.keywordTreatmentspa
dc.titleDisease of the Year 2019: Ocular Toxoplasmosis in HIV-infected Patientsspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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