Ítem
Acceso Abierto

Unveiling the pathogenic mechanisms of Clostridium perfringens toxins and virulence factors

Mostrar el registro sencillo de la publicación
dc.creatorCamargo, Aspa
dc.creatorRamírez González, Juan Davidspa
dc.creatorKiu, Rspa
dc.creatorHall LJspa
dc.creatorMuñoz, Marinaspa
dc.date.accessioned2025-01-26T18:37:14Z
dc.date.available2025-01-26T18:37:14Z
dc.date.created2024-12-01spa
dc.date.issued2024-12-01spa
dc.descriptionClostridium perfringens causes multiple diseases in humans and animals. Its pathogenic effect is supported by a broad and heterogeneous arsenal of toxins and other virulence factors associated with a specific host tropism. Molecular approaches have indicated that most C. perfringens toxins produce membrane pores, leading to osmotic cell disruption and apoptosis. However, identifying mechanisms involved in cell tropism and selective toxicity effects should be studied more. The differential presence and polymorphisms of toxin-encoding genes and genes encoding other virulence factors suggest that molecular mechanisms might exist associated with host preference, receptor binding, and impact on the hostspa
dc.descriptionhowever, this information has not been reviewed in detail. Therefore, this review aims to clarify the current state of knowledge on the structural features and mechanisms of action of the major toxins and virulence factors of C. perfringens and discuss the impact of genetic diversity of toxinotypes in tropism for several hosts.spa
dc.format.mimetypeapplication/pdfspa
dc.identifier.doihttps://doi.org/10.1080/22221751.2024.2341968spa
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/44848
dc.language.isoengspa
dc.publisherEmerging Microbes and Infectionsspa
dc.relation.ispartofEmerging Microbes and Infectionsspa
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internationalspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccessspa
dc.rights.accesoAbierto (Texto Completo)spa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/spa
dc.sourceEmerging Microbes and Infectionsspa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subjectClostridium perfringensspa
dc.subjecttoxin typespa
dc.subjectenteritisspa
dc.subjectgenetic diversityspa
dc.subjecthostspa
dc.subjecttoxinotypes.spa
dc.titleUnveiling the pathogenic mechanisms of Clostridium perfringens toxins and virulence factorsspa
dc.typearticlespa
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersionspa
dc.type.spaArtículospa
Archivos
Bloque original
Mostrando1 - 1 de 1
Miniatura
Nombre:
Unveiling_the_pathogenic_mechanisms_of_Clostridium.pdf
Tamaño:
1.79 MB
Formato:
Adobe Portable Document Format
Descripción:
Descargar
Colecciones
Artículos