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Autoimmune Thyroid Disease in Rheumatoid Arthritis: A Global Perspective

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dc.creatorRoldán, Jorge Cárdenasspa
dc.creatorAmaya-Amaya, Jennyspa
dc.creatorla Hoz, Juan Castellanos-despa
dc.creatorGiraldo-Villamil, Julianaspa
dc.creatorMontoya-Ortiz, Gladysspa
dc.creatorCruz-Tapias, Paolaspa
dc.creatorRojas-Villarraga, Adrianaspa
dc.creatorMantilla, Rubén D.spa
dc.creatorAnaya, Juan-Manuelspa
dc.date.accessioned2020-06-11T13:22:22Z
dc.date.available2020-06-11T13:22:22Z
dc.date.created2012-11-18spa
dc.description.abstractObjective. To determine the prevalence and impact of autoimmune thyroid disease (AITD) in patients with rheumatoid arthritis (RA). Methods. Eight-hundred patients were included. The association between AITD and RA was analyzed was analyzed by bivariate and multivariate analysis. In addition, a literature review was done focusing on geographical variations. Results. In our cohort the prevalence of AITD was 9.8% while the presence of antibodies was 37.8% for antithyroperoxidase enzyme (TPOAb) and 20.8% for antithyroglobulin protein (TgAb). The presence of type 2 diabetes, thrombosis, abnormal body mass index, and a high educational level was positively associated with AITD. The literature review disclosed a geographical variation of AITD in RA ranging from 0.5% to 27%. Autoantibody prevalence ranges from 6% to 31% for TgAb, 5% to 37% for TPOAb, and from 11.4% to 32% for the presence of either of the two. Conclusion. AITD is not uncommon in RA and should be systematically assessed since it is a risk factor for developing diabetes and cardiovascular disease. These results may help to further study the common mechanisms of autoimmune diseases, to improve patients' outcome, and to define public health policies. An international consensus to accurately diagnose AITD is warranted.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1155/2012/864907
dc.identifier.issn20901984
dc.identifier.issn20901992
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/25105
dc.language.isoeng
dc.publisherArthritisspa
dc.relation.citationStartPage864907
dc.relation.citationTitleArthritis
dc.relation.citationVolumeVol. 2012
dc.relation.ispartofArthritis, ISSN: 20901984, 20901992, Vol.2012, No. (2012-11-18); pp. 864907spa
dc.relation.urihttp://downloads.hindawi.com/journals/arthritis/2012/864907.pdfspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordMedical and Health Sciencesspa
dc.subject.keywordClinical Sciencesspa
dc.subject.keywordImmunologyspa
dc.titleAutoimmune Thyroid Disease in Rheumatoid Arthritis: A Global Perspectivespa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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