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Age and ocular toxoplasmosis: a narrative review

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dc.creatorPleyer, Uwespa
dc.creatorTaghavi Eraghi, Arminspa
dc.creatorMejía-Salgado, Germánspa
dc.creatorDe La Torre Cifuentes, Ligia Alejandraspa
dc.date.accessioned2025-07-21T16:42:43Z
dc.date.available2025-07-21T16:42:43Z
dc.date.created2025-01-01spa
dc.date.issued2025-01-01spa
dc.description.abstractToxoplasma gondii is an extremely “successful” opportunistic parasite that infects most warm-blooded animals, including humans. While the infection is generally largely asymptomatic, the infection of the eye presenting as ocular toxoplasmosis (OT) is a potentially blinding consequence. OT remains the most common cause of infectious retinochoroiditis and places a considerable socio-economic burden on societies, particularly in developing countries. Age is one of several factors influencing the clinical presentation and outcomes of OT. Older patients often exhibit more severe disease manifestations, larger retinal lesions, and poorer visual outcomes compared to younger individuals. This disparity is attributed to immunosenescence, the age-related decline in immune function, which impairs the body's ability to control the infection effectively. Consequently, older individuals are at a higher risk of severe complications and recurrent episodes of inflammation. Understanding the interplay between age and immune response is essential for developing targeted treatment strategies and improving patient outcomes in OT.eng
dc.format.mimetypeapplication/pdfspa
dc.identifier.doihttps://doi.org/10.1093/femsmc/xtaf002spa
dc.identifier.issn2633-6685spa
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/46067
dc.language.isoengspa
dc.publisherOxford Academicspa
dc.relation.ispartofFEMS Microbes, Volume 6, 2025spa
dc.relation.urihttps://academic.oup.com/femsmicrobes/article/doi/10.1093/femsmc/xtaf002/8043260spa
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internationalspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccessspa
dc.rights.accesoAbierto (Texto Completo)spa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/spa
dc.sourceFEMS Microbesspa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordVirologíaeng
dc.subject.keywordAgeeng
dc.subject.keywordOculareng
dc.subject.keywordToxoplasmosiseng
dc.subject.keywordNarrativeeng
dc.subject.keywordRevieweng
dc.subject.keywordRisc factorseng
dc.titleAge and ocular toxoplasmosis: a narrative reviewspa
dc.typearticlespa
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersionspa
dc.type.spaArtículo de revisiónspa
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